Search Results - "Anarbaev, Rashid O"

Quantitative characterization of protein-protein complexes involved in base excision DNA repair by Moor, Nina A, Vasil'eva, Inna A, Anarbaev, Rashid O, Antson, Alfred A, Lavrik, Olga I

“…Base Excision Repair (BER) efficiently corrects the most common types of DNA damage in mammalian cells. Step-by-step coordination of BER is facilitated by…”
Get full text

DNA Repair Protein XRCC1 Stimulates Activity of DNA Polymerase λ under Conditions of Microphase Separation by Lebedeva, Natalia A, Anarbaev, Rashid O, Maltseva, Ekaterina A, Sukhanova, Maria V, Rechkunova, Nadejda I, Lavrik, Olga I

“…Non-membrane compartments or biomolecular condensates play an important role in the regulation of cellular processes including DNA repair. Here, an ability of…”
Get full text

FUS Microphase Separation: Regulation by Nucleic Acid Polymers and DNA Repair Proteins by Sukhanova, Maria V., Anarbaev, Rashid O., Maltseva, Ekaterina A., Pastré, David, Lavrik, Olga I.

“…Fused in sarcoma (FUS) is involved in the regulation of RNA and DNA metabolism. FUS participates in the formation of biomolecular condensates driven by phase…”
Get full text

New Hybrid Compounds Combining Fragments of Usnic Acid and Thioether Are Inhibitors of Human Enzymes TDP1, TDP2 and PARP1 by Dyrkheeva, Nadezhda S, Filimonov, Aleksandr S, Luzina, Olga A, Orlova, Kristina A, Chernyshova, Irina A, Kornienko, Tatyana E, Malakhova, Anastasia A, Medvedev, Sergey P, Zakharenko, Alexandra L, Ilina, Ekaterina S, Anarbaev, Rashid O, Naumenko, Konstantin N, Klabenkova, Kristina V, Burakova, Ekaterina A, Stetsenko, Dmitry A, Zakian, Suren M, Salakhutdinov, Nariman F, Lavrik, Olga I

“…Tyrosyl-DNA phosphodiesterase 1 (TDP1) catalyzes the cleavage of the phosphodiester bond between the tyrosine residue of topoisomerase 1 (TOP1) and the 3'…”
Get full text

The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme by Gladkova, Elizaveta D, Nechepurenko, Ivan V, Bredikhin, Roman A, Chepanova, Arina A, Zakharenko, Alexandra L, Luzina, Olga A, Ilina, Ekaterina S, Dyrkheeva, Nadezhda S, Mamontova, Evgeniya M, Anarbaev, Rashid O, Reynisson, Jóhannes, Volcho, Konstantin P, Salakhutdinov, Nariman F, Lavrik, Olga I

“…A series of berberine and tetrahydroberberine sulfonate derivatives were prepared and tested against the tyrosyl-DNA phosphodiesterase 1 (Tdp1) DNA-repair…”
Get full text

Divalent and multivalent cations control liquid-like assembly of poly(ADP-ribosyl)ated PARP1 into multimolecular associates in vitro by Sukhanova, Maria V., Anarbaev, Rashid O., Maltseva, Ekaterina A., Kutuzov, Mikhail M., Lavrik, Olga I.

“…The formation of nuclear biomolecular condensates is often associated with local accumulation of proteins at a site of DNA damage. The key role in the…”
Get full text

The C-Terminal Domain of Y-Box Binding Protein 1 Exhibits Structure-Specific Binding to Poly(ADP-Ribose), Which Regulates PARP1 Activity by Naumenko, Konstantin N, Sukhanova, Mariya V, Hamon, Loic, Kurgina, Tatyana A, Anarbaev, Rashid O, Mangerich, Aswin, Pastré, David, Lavrik, Olga I

“…Y-box-binding protein 1 (YB-1) is a multifunctional protein involved in the regulation of gene expression. Recent studies showed that in addition to its role…”
Get full text

Poly(ADP-ribose)polymerase 1 stimulates the AP-site cleavage activity of tyrosyl-DNA phosphodiesterase 1 by Lebedeva, Natalia A, Anarbaev, Rashid O, Sukhanova, Maria, Vasil'eva, Inna A, Rechkunova, Nadejda I, Lavrik, Olga I

“…The influence of poly(ADP-ribose)polymerase 1 (PARP1) on the apurinic/apyrimidinic (AP)-site cleavage activity of tyrosyl-DNA phosphodiesterase 1 (TDP1) and…”
Get full text

Single molecule detection of PARP1 and PARP2 interaction with DNA strand breaks and their poly(ADP-ribosyl)ation using high-resolution AFM imaging by Sukhanova, Maria V, Abrakhi, Sanae, Joshi, Vandana, Pastre, David, Kutuzov, Mikhail M, Anarbaev, Rashid O, Curmi, Patrick A, Hamon, Loic, Lavrik, Olga I

“…PARP1 and PARP2 are implicated in the synthesis of poly(ADP-ribose) (PAR) after detection of DNA damage. The specificity of PARP1 and PARP2 interaction with…”
Get full text

Dynamic light scattering study of base excision DNA repair proteins and their complexes by Vasil'eva, Inna A., Anarbaev, Rashid O., Moor, Nina A., Lavrik, Olga I.

“…Base excision repair (BER) involves many enzymes acting in a coordinated fashion at the most common types of DNA damage. The coordination is facilitated by…”
Get full text

Deoxycholic acid as a molecular scaffold for tyrosyl-DNA phosphodiesterase 1 inhibition: A synthesis, structure–activity relationship and molecular modeling study by Salomatina, Oksana V., Popadyuk, Irina I., Zakharenko, Alexandra L., Zakharova, Olga D., Chepanova, Arina A., Dyrkheeva, Nadezhda.S., Komarova, Nina I., Reynisson, Jóhannes, Anarbaev, Rashid O., Salakhutdinov, Nariman F., Lavrik, Olga I., Volcho, Konstantin P.

“…[Display omitted] •para-Bromoanilides of deoxycholic acid derivatives were designed and synthesized.•All target compounds were evaluated as inhibitors of…”
Get full text

The multifunctional protein YB-1 potentiates PARP1 activity and decreases the efficiency of PARP1 inhibitors by Alemasova, Elizaveta E, Naumenko, Konstantin N, Kurgina, Tatyana A, Anarbaev, Rashid O, Lavrik, Olga I

“…Y-box-binding protein 1 (YB-1) is a multifunctional cellular factor overexpressed in tumors resistant to chemotherapy. An intrinsically disordered structure…”
Get full text

Design of a New Fluorescent Oligonucleotide-Based Assay for a Highly Specific Real-Time Detection of Apurinic/Apyrimidinic Site Cleavage by Tyrosyl-DNA Phosphodiesterase 1 by Lebedeva, Natalia A, Anarbaev, Rashid O, Kupryushkin, Maxim S, Rechkunova, Nadejda I, Pyshnyi, Dmitrii V, Stetsenko, Dmitry A, Lavrik, Olga I

“…Tyrosyl-DNA phosphodiesterase 1 (Tdp1) promotes catalytic scission of a phosphodiester bond between the 3′-end of DNA and the hydroxyl group of a tyrosine…”
Get full text

Synthesis of the conjugates of DNA polymerase β with cadmium sulfide nanoparticles and their activity in reverse micelles by Anarbaev, Rashid O., Vasil’eva, Inna A., Lavrik, Olga I.

“…•We synthesized cadmium sulfide nanoparticles with infinite solubility in water.•We obtained the smallest DNA polymerase β-CdS nanoparticle conjugates.•We…”
Get full text

Human and yeast DNA damage recognition complexes bind with high affinity DNA structures mimicking in size transcription bubble by Krasikova, Yuliya S., Rechkunova, Nadejda I., Maltseva, Ekaterina A., Anarbaev, Rashid O., Pestryakov, Pavel E., Sugasawa, Kaoru, Min, Jung-Hyun, Lavrik, Olga I.

“…The human XPC‐RAD23B complex and its yeast ortholog, Rad4‐Rad23, are the primary initiators of global genome nucleotide excision repair. In this study, two…”
Get full text

DNA polymerase β reveals enhanced activity and processivity in reverse micelles by Anarbaev, Rashid O., Rogozina, Anastasia L., Lavrik, Olga I.

“…Water is essential for the stability and functions of proteins and DNA. Reverse micelles are simple model systems where the structure and dynamics of water are…”
Get full text

Abstract P-21: The Oligomeric State of Base Excision DNA Repair Proteins and Their Complexes Explored by Dynamic Light Scattering by Vasil’eva, Inna, Moor, Nina, Anarbaev, Rashid, Lavrik, Olga

“…Background: Base excision DNA repair (BER) is very efficient process that involves the action of many enzymes and accessory proteins to correct the most common…”
Get full text

DNA polymerase β reveals enhanced stability in reverse microemulsions by Anarbaev, Rashid O., Rogozina, Anastasia L., Lavrik, Olga I.

“…Water is essential for the stability and functions of proteins and DNA. Reverse microemulsions are model systems where the structure and dynamics of water are…”
Get full text

Klenow fragment and DNA polymerase α-primase fromserva calf thymus in water-in-oil microemulsions by Anarbaev, Rashid O, Elepov, Ilja B, Lavrik, Olga I

“…The activity of DNA polymerase α-primase complex from calf thymus and Klenow fragment of E. coli DNA polymerase 1 has been studied in reverse microemulsions…”
Get full text

DNA polymerase β reveals enhanced stability in reverse microemulsions by ANARBAEV, Rashid O, ROGOZINA, Anastasia L, LAVRIK, Olga I

Get full text