Search Results - "Anapindi, Krishna D.B."
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1
Assessment and Comparison of Database Search Engines for Peptidomic Applications
Published in Journal of proteome research (06-10-2023)“…Protein database search engines are an integral component of mass spectrometry-based peptidomic analyses. Given the unique computational challenges of…”
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Mass Spectrometry Approaches Empowering Neuropeptide Discovery and Therapeutics
Published in Pharmacological reviews (01-07-2022)“…The discovery of insulin in the early 1900s ushered in the era of research related to peptides acting as hormones and neuromodulators, among other regulatory…”
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PACAP and Other Neuropeptide Targets Link Chronic Migraine and Opioid-induced Hyperalgesia in Mouse Models
Published in Molecular & cellular proteomics (01-12-2019)“…The neuropeptides within seven nervous system regions involved in relaying pain signals have been identified and quantified in mouse models of chronic migraine…”
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Peptide identifications and false discovery rates using different mass spectrometry platforms
Published in Talanta (Oxford) (15-05-2018)“…Characterization of endogenous neuropeptides produced from post-translational proteolytic processing of precursor proteins is a demanding task. A variety of…”
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Neuropeptidomics of the Rat Habenular Nuclei
Published in Journal of proteome research (06-04-2018)“…Conserved across vertebrates, the habenular nuclei are a pair of small symmetrical structures in the epithalamus. The nuclei functionally link the forebrain…”
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Improved identification and quantitation of mature endogenous peptides in the rodent hypothalamus using a rapid conductive sample heating system
Published in Analyst (London) (20-11-2017)“…Measurement, identification, and quantitation of endogenous peptides in tissue samples by mass spectrometry (MS) contribute to our understanding of the complex…”
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Quantitative Characterization of the Neuropeptide Level Changes in Dorsal Horn and Dorsal Root Ganglia Regions of the Murine Itch Models
Published in Journal of proteome research (06-03-2020)“…Chronic itch can be extremely devastating and, in many cases, difficult to treat. One challenge in treating itch disorders is the limited understanding of the…”
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