Search Results - "Anaparti, Vidyanand"

Whole blood microRNA expression pattern differentiates patients with rheumatoid arthritis, their seropositive first-degree relatives, and healthy unrelated control subjects by Anaparti, Vidyanand, Smolik, Irene, Meng, Xiaobo, Spicer, Victor, Mookherjee, Neeloffer, El-Gabalawy, Hani

“…Epigenetic mechanisms can integrate gene-environment interactions that mediate disease transition from preclinical to clinically overt rheumatoid arthritis…”
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A bioavailable form of curcumin, in combination with vitamin-D- and omega-3-enriched diet, modifies disease onset and outcomes in a murine model of collagen-induced arthritis by Hemshekhar, Mahadevappa, Anaparti, Vidyanand, El-Gabalawy, Hani, Mookherjee, Neeloffer

“…Curcumin (CUR), vitamin D (D3), and omega-3-fatty acids (O3FA) individually modulate inflammation and pain in arthritis. Although these supplements are widely…”
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Functions of Cationic Host Defense Peptides in Immunity by Hemshekhar, Mahadevappa, Anaparti, Vidyanand, Mookherjee, Neeloffer

“…Cationic host defense peptides are a widely distributed family of immunomodulatory molecules with antimicrobial properties. The biological functions of these…”
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Circulating levels of free 25(OH)D increase at the onset of rheumatoid arthritis by Anaparti, Vidyanand, Meng, Xiaobo, Hemshekhar, Mahadevappa, Smolik, Irene, Mookherjee, Neeloffer, El-Gabalawy, Hani

“…Epidemiological studies suggest vitamin D deficiency as a potential risk factor for rheumatoid arthritis (RA) development, a chronic autoimmune disorder highly…”
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Lipoxygenase-derived oxylipins are enriched in anti-citrullinated protein antibody (ACPA)-positive individuals at risk for developing rheumatoid arthritis by O'Neil, Liam J, Anaparti, Vidyanand, Winter, Tanja, Smolik, Irene, Meng, Xiaobo, Aukema, Harold M, El-Gabalawy, Hani

“…Rheumatoid arthritis (RA) is typically preceded by an extended preclinical period where circulating autoantibodies, particularly anti-citrullinated protein…”
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Buprenorphine Alters Inflammatory and Oxidative Stress Molecular Markers in Arthritis by Mookherjee, Neeloffer, Hitchon, Carol, Anaparti, Vidyanand, Hemshekhar, Mahadevappa

“…Buprenorphine is recommended for use as an analgesic in animal models including in murine models of collagen-induced arthritis (CIA). However, the effect of…”
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Increased frequency of TIGIT+ CD4 T Cell subset in autoantibody-positive first-degree relatives of patients with rheumatoid arthritis by Anaparti, Vidyanand, Tanner, Stacy, Zhang, Christine, O’Neil, Liam, Smolik, Irene, Meng, Xiaobo, Marshall, Aaron J., El-Gabalawy, Hani

“…Background Despite immune cell dysregulation being an important event preceding the onset of rheumatoid arthritis (RA), the phenotype of T and B cells in…”
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Proteomic Approaches to Defining Remission and the Risk of Relapse in Rheumatoid Arthritis by O'Neil, Liam J, Hu, Pingzhao, Liu, Qian, Islam, Md Mohaiminul, Spicer, Victor, Rech, Juergen, Hueber, Axel, Anaparti, Vidyanand, Smolik, Irene, El-Gabalawy, Hani S, Schett, Georg, Wilkins, John A

“…Patients with Rheumatoid Arthritis (RA) are increasingly achieving stable disease remission, yet the mechanisms that govern ongoing clinical disease and…”
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Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis by Scally, Stephen W, Law, Soi-Cheng, Ting, Yi Tian, Heemst, Jurgen van, Sokolove, Jeremy, Deutsch, Aaron J, Bridie Clemens, E, Moustakas, Antonis K, Papadopoulos, George K, van der Woude, Diane, Smolik, Irene, Hitchon, Carol A, Robinson, David B, Ferucci, Elizabeth D, Bernstein, Charles N, Meng, Xiaobo, Anaparti, Vidyanand, Huizinga, Tom, Kedzierska, Katherine, Reid, Hugh H, Raychaudhuri, Soumya, Toes, René E, Rossjohn, Jamie, El-Gabalawy, Hani, Thomas, Ranjeny

“…The pathogenetic mechanisms by which alleles are associated with anticitrullinated peptide antibody (ACPA)-positive rheumatoid arthritis (RA) are incompletely…”
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Can Studying Genetically Predisposed Individuals Inform Prevention Strategies for RA? by Fowler-Woods, Amanda, Smolik, Irene, Anaparti, Vidyanand, O'Neil, Liam, El-Gabalawy, Hani

“…Rheumatoid arthritis (RA) is a prevalent autoimmune disorder in which complex genetic predisposition interacts with multiple environmental factors to…”
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Utility of Baseline Transcriptomic Analysis of Rheumatoid Arthritis Synovium as an Indicator for Long-Term Clinical Outcomes by Anaparti, Vidyanand, Wiens, Dana, O'Neil, Liam J, Hubbard, Erika, Robl, Robert, Smolik, Irene, Hitchon, Carol, Lipsky, Peter E, El-Gabalawy, Hani

“…Rheumatoid arthritis is a chronic inflammatory autoimmune disease that can lead to synovial damage, persistent joint pain, and functional disability. Our…”
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What's new in asthma pathophysiology and immunopathology? by Orihara, Kanami, Dil, Nyla, Anaparti, Vidyanand, Moqbel, Redwan

“…Research on asthma pathophysiology over the past decade has expanded the complex repertoire involved in the pathophysiology of asthma to include inflammatory,…”
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Expression and roles of glutamate (NMDA) receptors on T cell subsets by Orihara, Kanami, Odemuyiwa, Solomon O, Dil, Nyla, Anaparti, Vidyanand, Moqbel, Redwan

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Whole Blood Targeted Bisulfite Sequencing and Differential Methylation in the C6ORF10 Gene of Patients with Rheumatoid Arthritis by Anaparti, Vidyanand, Agarwal, Prasoon, Smolik, Irene, Mookherjee, Neeloffer, El-Gabalawy, Hani

“…Polymorphisms in human major histocompatibility complex (MHC) are the strongest genetic associations with rheumatoid arthritis (RA). Epigenome-wide methylation…”
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A Prospective Study of the Development of Inflammatory Arthritis in the Family Members of Indigenous North American People With Rheumatoid Arthritis by Tanner, Stacy, Dufault, Brenden, Smolik, Irene, Meng, Xiaobo, Anaparti, Vidyanand, Hitchon, Carol, Robinson, David B., Robinson, William, Sokolove, Jeremy, Lahey, Lauren, Ferucci, Elizabeth D., El‐Gabalawy, Hani

“…Objective To determine the incidence of inflammatory arthritis and autoantibody prevalence in Indigenous North American people. Methods Unaffected relatives of…”
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Functional Disability to Evaluate the Risk of Arthritis in First-degree Relatives of Patients With Rheumatoid Arthritis by Wiens, Dana, Smolik, Irene, Meng, Xiaobo, Anaparti, Vidyanand, El-Gabalawy, Hani S, O'Neil, Liam J

“…The events that occur prior to the onset of rheumatoid arthritis (RA) continue to be delineated. We examined the relationship between self-reported joint…”
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Association of a Serum Protein Signature With Rheumatoid Arthritis Development by O’Neil, Liam J., Spicer, Victor, Smolik, Irene, Meng, Xiaobo, Goel, Rishi R., Anaparti, Vidyanand, Wilkins, John, El‐Gabalawy, Hani S.

“…Objective The pathophysiologic events that precede the onset of rheumatoid arthritis (RA) remain incompletely understood. This study was undertaken to identify…”
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Expansion of Alternative Autoantibodies Does Not Follow the Evolution of Anti–Citrullinated Protein Antibodies in Preclinical Rheumatoid Arthritis: An Analysis in At‐Risk First Degree Relatives by Anaparti, Vidyanand, Smolik, Irene, Meng, Xiaobo, O’Neil, Liam, Jantz, Mackenzie A., Fritzler, Marvin J., El‐Gabalawy, Hani

“…Objective Co‐occurrence of autoantibodies specific for ≥1 autoimmune disease is widely prevalent in rheumatoid arthritis (RA) patients. To understand the…”
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Tumor necrosis factor regulates NMDA receptor-mediated airway smooth muscle contractile function and airway responsiveness by Anaparti, Vidyanand, Pascoe, Christopher D, Jha, Aruni, Mahood, Thomas H, Ilarraza, Ramses, Unruh, Helmut, Moqbel, Redwan, Halayko, Andrew J

“…We have shown that N-methyl-d-aspartate receptors (NMDA-Rs) are receptor-operated calcium entry channels in human airway smooth muscle (HASM) during…”
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NMDA receptors mediate contractile responses in human airway smooth muscle cells by Anaparti, Vidyanand, Ilarraza, Ramses, Orihara, Kanami, Stelmack, Gerald L, Ojo, Oluwaseun O, Mahood, Thomas H, Unruh, Helmut, Halayko, Andrew J, Moqbel, Redwan

“…Human airway smooth muscle (HASM) exhibits enhanced contractility in asthma. Inflammation is associated with airway hypercontractility, but factors that…”
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