Search Results - "Ananthakrishnan, N."

Environmental Risk Factors for Inflammatory Bowel Diseases: A Review by Ananthakrishnan, Ashwin N.

“…Inflammatory bowel diseases comprising Crohn’s disease (CD) and ulcerative colitis (UC) are chronic immunologically mediated diseases. The key mechanism…”
Get full text

Epidemiology and risk factors for IBD by Ananthakrishnan, Ashwin N.

“…Key Points Crohn's disease and ulcerative colitis are complex immunologically mediated diseases that arise due to a dysregulated immune response to commensal…”
Get full text

ACG Clinical Guideline: Ulcerative Colitis in Adults by Rubin, David T, Ananthakrishnan, Ashwin N, Siegel, Corey A, Sauer, Bryan G, Long, Millie D

“…Ulcerative colitis (UC) is an idiopathic inflammatory disorder. These guidelines indicate the preferred approach to the management of adults with UC and…”
Get full text

Clostridium difficile infection: epidemiology, risk factors and management by Ananthakrishnan, Ashwin N

“…Clostridium difficile is as an important health-care-associated pathogen and is linked to significant morbidity, economic burden, and even mortality. A…”
Get full text

Microbiome-Based Biomarkers for IBD by Ananthakrishnan, Ashwin N

“…Abstract Crohn disease and ulcerative colitis are complex immune-mediated diseases that are characterized by a heterogeneity in presentation and clinical…”
Get full text

Treat to Target: The Role of Histologic Healing in Inflammatory Bowel Diseases: A Systematic Review and Meta-analysis by Gupta, Akshita, Yu, Amy, Peyrin-Biroulet, Laurent, Ananthakrishnan, Ashwin N.

“…Endoscopic remission is a recognized therapeutic endpoint in inflammatory bowel disease (IBD; Crohn’s disease (CD), ulcerative colitis (UC)). The impact of…”
Get full text

The emergence of Clostridium difficile infection in Asia: A systematic review and meta-analysis of incidence and impact by Borren, Nienke Z, Ghadermarzi, Shadi, Hutfless, Susan, Ananthakrishnan, Ashwin N

“…Clostridium difficile infection (CDI) is the most common healthcare associated infection and is highly prevalent in Europe and North America. Limited data is…”
Get full text

Ulcerative Colitis and Crohn’s Disease Have Similar Burden and Goals for Treatment by Le Berre, Catherine, Ananthakrishnan, Ashwin N., Danese, Silvio, Singh, Siddharth, Peyrin-Biroulet, Laurent

“…It is unclear whether ulcerative colitis (UC) is a progressive disease similar to Crohn’s disease (CD). Patients with UC often are undertreated because of the…”
Get full text

Review article: vitamin D and inflammatory bowel diseases by Mouli, V. P., Ananthakrishnan, A. N.

“…Summary Background Vitamin D is traditionally associated with bone metabolism. The immunological effects of vitamin D have increasingly come into focus. Aim To…”
Get full text

Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis by Smillie, Christopher S., Biton, Moshe, Ordovas-Montanes, Jose, Sullivan, Keri M., Burgin, Grace, Graham, Daniel B., Herbst, Rebecca H., Rogel, Noga, Slyper, Michal, Waldman, Julia, Sud, Malika, Andrews, Elizabeth, Velonias, Gabriella, Haber, Adam L., Jagadeesh, Karthik, Vickovic, Sanja, Yao, Junmei, Stevens, Christine, Dionne, Danielle, Nguyen, Lan T., Villani, Alexandra-Chloé, Hofree, Matan, Creasey, Elizabeth A., Huang, Hailiang, Rozenblatt-Rosen, Orit, Garber, John J., Khalili, Hamed, Desch, A. Nicole, Daly, Mark J., Ananthakrishnan, Ashwin N., Shalek, Alex K., Xavier, Ramnik J., Regev, Aviv

“…Genome-wide association studies (GWAS) have revealed risk alleles for ulcerative colitis (UC). To understand their cell type specificities and pathways of…”
Get full text

Gut Microbiome Function Predicts Response to Anti-integrin Biologic Therapy in Inflammatory Bowel Diseases by Ananthakrishnan, Ashwin N., Luo, Chengwei, Yajnik, Vijay, Khalili, Hamed, Garber, John J., Stevens, Betsy W., Cleland, Thomas, Xavier, Ramnik J.

“…The gut microbiome plays a central role in inflammatory bowel diseases (IBDs) pathogenesis and propagation. To determine whether the gut microbiome may predict…”
Get full text

The role of diet in the aetiopathogenesis of inflammatory bowel disease by Khalili, Hamed, Chan, Simon S. M., Lochhead, Paul, Ananthakrishnan, Ashwin N., Hart, Andrew R., Chan, Andrew T.

“…Crohn’s disease and ulcerative colitis, collectively known as IBD, are chronic inflammatory disorders of the gastrointestinal tract. Although the…”
Get full text

AGA Clinical Practice Update on Management of Inflammatory Bowel Disease in Elderly Patients: Expert Review by Ananthakrishnan, Ashwin N., Nguyen, Geoffrey C., Bernstein, Charles N.

Get full text

Multi-omics reveal microbial determinants impacting responses to biologic therapies in inflammatory bowel disease by Lee, Jonathan Wei Jie, Plichta, Damian, Hogstrom, Larson, Borren, Nynke Z., Lau, Helena, Gregory, Sara M., Tan, William, Khalili, Hamed, Clish, Clary, Vlamakis, Hera, Xavier, Ramnik J., Ananthakrishnan, Ashwin N.

“…The intestinal microbiome is a key determinant of responses to biologic therapy in inflammatory bowel disease (IBD). However, diverse therapeutics and variable…”
Get full text

Development of phenotype algorithms using electronic medical records and incorporating natural language processing by Liao, Katherine P, Cai, Tianxi, Savova, Guergana K, Murphy, Shawn N, Karlson, Elizabeth W, Ananthakrishnan, Ashwin N, Gainer, Vivian S, Shaw, Stanley Y, Xia, Zongqi, Szolovits, Peter, Churchill, Susanne, Kohane, Isaac

“…Electronic medical records are emerging as a major source of data for clinical and translational research studies, although phenotypes of interest need to be…”
Get full text

A Prospective Study of Long-term Intake of Dietary Fiber and Risk of Crohn's Disease and Ulcerative Colitis by Ananthakrishnan, Ashwin N, Khalili, Hamed, Konijeti, Gauree G, Higuchi, Leslie M, de Silva, Punyanganie, Korzenik, Joshua R, Fuchs, Charles S, Willett, Walter C, Richter, James M, Chan, Andrew T

“…Background & Aims Increased intake of dietary fiber has been proposed to reduce the risk of inflammatory bowel disease (Crohn's disease [CD] and ulcerative…”
Get full text

A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients by Hall, Andrew Brantley, Yassour, Moran, Sauk, Jenny, Garner, Ashley, Jiang, Xiaofang, Arthur, Timothy, Lagoudas, Georgia K, Vatanen, Tommi, Fornelos, Nadine, Wilson, Robin, Bertha, Madeline, Cohen, Melissa, Garber, John, Khalili, Hamed, Gevers, Dirk, Ananthakrishnan, Ashwin N, Kugathasan, Subra, Lander, Eric S, Blainey, Paul, Vlamakis, Hera, Xavier, Ramnik J, Huttenhower, Curtis

“…Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract that is associated with changes in the gut microbiome…”
Get full text

Long-term intake of dietary fat and risk of ulcerative colitis and Crohn's disease by Ananthakrishnan, Ashwin N, Khalili, Hamed, Konijeti, Gauree G, Higuchi, Leslie M, de Silva, Punyanganie, Fuchs, Charles S, Willett, Walter C, Richter, James M, Chan, Andrew T

“…Dietary fats influence intestinal inflammation and regulate mucosal immunity. Data on the association between dietary fat and risk of Crohn's disease (CD) and…”
Get more information

Systematic review with meta‐analysis: comparative efficacy of biologics for induction and maintenance of mucosal healing in Crohn's disease and ulcerative colitis controlled trials by Cholapranee, A., Hazlewood, G. S, Kaplan, G. G., Peyrin‐Biroulet, L., Ananthakrishnan, A. N.

“…Summary Background Mucosal healing is an important therapeutic endpoint in the management of Crohn's disease (CD) and ulcerative colitis (UC). Limited data…”
Get full text

Promoting research for undergraduates of medicine in India – A critical necessity by Ananthakrishnan, N

Get full text