Search Results - "Anania, F A"

Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways by Sharma, D, Saxena, N K, Vertino, P M, Anania, F A

“…An increase in the risk of cancer is one of the consequences of obesity. The predominant cancers associated with obesity have a hormonal basis and include…”
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The Natural History of Hepatitis C Virus Infection: Host, Viral, and Environmental Factors by Thomas, David L, Astemborski, Jacquie, Rai, Rudra M, Anania, Frank A, Schaeffer, Melody, Galai, Noya, Nolt, Karen, Nelson, Kenrad E, Strathdee, Steffanie A, Johnson, Lisette, Laeyendecker, Oliver, Boitnott, John, Wilson, Lucy E, Vlahov, David

“…CONTEXT Hepatitis C virus (HCV) infection may resolve (viral clearance), persist without complications, or cause end-stage liver disease (ESLD). The frequency…”
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Peroxisome Proliferator-activated Receptors and Hepatic Stellate Cell Activation by Miyahara, Takeo, Schrum, Laura, Rippe, Richard, Xiong, Shigang, Yee, Hal F., Motomura, Kenta, Anania, Frank A., Willson, Timothy M., Tsukamoto, Hidekazu

“…The present study examined the roles of peroxisome proliferator-activated receptors (PPAR) in activation of hepatic stellate cells (HSC), a pivotal event in…”
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Randomised, double blind, placebo controlled trial of interferon, ribavirin, and amantadine versus interferon, ribavirin, and placebo in treatment naïve patients with chronic hepatitis C by Thuluvath, P J, Maheshwari, A, Mehdi, J, Fairbanks, K D, Wu, L L-W, Gelrud, L G, Ryan, M J, Anania, F A, Lobis, I F, Black, M

“…Background and aim: In this study, we compared the efficacy of triple therapy (interferon alfa, ribavirin, and amantadine) with standard therapy (interferon…”
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An Assessment of Statin Safety by Hepatologists by Cohen, David E., Anania, Frank A., Chalasani, Naga

“…The purpose of the Liver Expert Panel was to provide advice to the National Lipid Association’s (NLA) Safety Task Force in response to specific questions…”
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A transient increase in c-myc precedes the transdifferentiation of hepatic stellate cells to myofibroblast-like cells by Potter, James J., Rennie-Tankersley, Lynda, Anania, Frank A., Mezey, Esteban

“…: Aims/Background: Liver stellate cells are transdifferentiated to collagen‐producing myofibroblast‐like cells in vivo during liver injury or when placed in…”
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Transdifferentiation of Rat Hepatic Stellate Cells Results in Leptin Expression by Potter, James J., Womack, Lawrence, Mezey, Esteban, Anania, Frank A.

“…Leptin is a peptide hormone that appears critical in regulating Fat metabolism. Recently, circulating leptin levels were reported higher in patients with…”
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Aldehydes potentiate alpha(2)(I) collagen gene activity by JNK in hepatic stellate cells by Anania, F A, Womack, L, Jiang, M, Saxena, N K

“…Hepatic stellate cells (HSCs) are responsible for type I collagen deposition in liver fibrosis that leads to cirrhosis. The purpose of this study was to…”
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Leptin, liver, and obese mice—Fibrosis in the fat lane by Anania, Frank A.

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Which patients with hepatitis C virus should be treated? by Shamoun, D K, Anania, F A

“…Since the National Institutes of Health (NIH) Consensus Conference in 1997, our understanding of the natural history of hepatitis C (HCV) infection and our…”
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Delayed granuloma formation in a patient with vanishing bile duct syndrome 7 years post–liver transplantation by Anania, Frank A., Howell, Charles D., Laurin, Jacqueline M., Drachenberg, Cinthia I.

“…A patient was found to have numerous granulomata 7 years after orthotopic liver transplantation for primary sclerosing cholangitis (PSC) on a recent liver…”
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Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice by XIAOKUN DING, SAXENA, Neeraj K, SONGBAI LIN, GUPTA, Narita, ANANIA, Frank A

“…Nonalcoholic fatty liver disease (NAFLD) represents a burgeoning problem in hepatology, and is associated with insulin resistance. Exendin-4 is a peptide…”
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Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells by ALEFFI, Sara, PETRAI, Ilaria, LATH, Giacomo, PINZNLI, Massimo, MARRA, Fabio, BERTOLALI, Cristiana, PAROLA, Maurizio, COLOMBATTO, Sebastiano, NOVO, Erica, VIZMTTI, Francesco, ANANIA, Frank A, MILANI, Stefano, ROMBOUTS, Krista

“…Leptin upregulates collagen expression in hepatic stellate cells (HSCs), but the possible modulation of other actions has not been elucidated. The aim of this…”
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The Roles of Leptin and Adiponectin: A Novel Paradigm in Adipocytokine Regulation of Liver Fibrosis and Stellate Cell Biology by Ding, Xiaokun, Saxena, Neeraj K, Lin, Songbai, Xu, Amin, Srinivasan, Shanthi, Anania, Frank A

“…Although leptin is a key adipokine promoting liver fibrosis, adiponectin may prevent liver injury. To determine the role of these adipokines in liver fibrosis…”
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Leptin in hepatic fibrosis: Evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice by Saxena, Neeraj K., Ikeda, Kazuo, Rockey, Don C., Friedman, Scott L., Anania, Frank A.

“…Leptin is a 16-kd hormone that mediates a range of metabolic effects by using a transduction pathway from the long form of the leptin receptor, OB-RL, through…”
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Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation by Saxena, Neeraj K., Titus, Mark A., Ding, Xiaokun, Floyd, Jeffrey, Srinivasan, Shanthi, Sitaraman, Shanthi V., Anania, Frank A.

“…ABSTRACT A key feature in the molecular pathogenesis of liver fibrosis requires maintenance of the activated hepatic stellate cell (HSC) phenotype by both…”
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Adiponectin and alcoholic fatty liver: Is it, after all, about what you eat? by Anania, Frank A

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Aldehydes potentiate alpha sub(2)(I) collagen gene activity by JNK in hepatic stellate cells by Anania, F A, Womack, L, Jiang, M, Saxena, N K

“…Hepatic stellate cells (HSCs) are responsible for type I collagen deposition in liver fibrosis that leads to cirrhosis. The purpose of this study was to…”
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Leptin induces increased alpha 2(I) collagen gene expression in cultured rat hepatic stellate cells by Saxena, Neeraj K, Saliba, George, Floyd, Jeffrey J, Anania, Frank A

“…Leptin is a 16-kDa hormone with an array of biologic actions. We, and others, have demonstrated that leptin is critical to the development of liver…”
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Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver by Jadaho, Sanjay B., Yang, Rong‐Ze, Lin, Qiang, Hu, Hong, Anania, Frank A., Shuldiner, Alan R., Gong, Da‐Wei

“…Alanine aminotransferase (ALT) is a widely used index of liver integrity or hepatocellular damage in clinics as well as a key enzyme in intermediatary…”
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