Ticagrelor-Induced Complete Heart Block: A Rare Entity

Ticagrelor, a purinergic P2Y12 receptor blocker, is a potent platelet antagonist and an important component in the treatment for acute coronary syndromes identified to have a potential risk to cause bradyarrhythmias. Here, we report the case of a diabetic patient of unstable angina with left bundle...

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Bibliographic Details
Published in:	Journal of pharmacology & pharmacotherapeutics Vol. 11; no. 2; pp. 75 - 77
Main Authors:	Anand, Wagle Varun, khadke, Isha, Padmakumar, R, Rao, M Sudhakar, Chogtu, Bharti
Format:	Journal Article
Language:	English
Published:	New Delhi, India SAGE Publications 01-04-2020 Wolters Kluwer India Pvt. Ltd Medknow Publications and Media Pvt. Ltd Sage Publications Ltd
Subjects:	Care and treatment Coronary heart disease Diabetics Electrocardiography Heart block Platelet aggregation inhibitors Type 2 diabetes purinergic P2Y receptor antagonist Heart block ticagrelor
Online Access:	Get full text
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Summary:	Ticagrelor, a purinergic P2Y12 receptor blocker, is a potent platelet antagonist and an important component in the treatment for acute coronary syndromes identified to have a potential risk to cause bradyarrhythmias. Here, we report the case of a diabetic patient of unstable angina with left bundle branch block who was prescribed ticagrelor post angioplasty. Electrocardiogram (ECG) revealed a complete heart block after about 1 week. Ticagrelor was stopped and replaced by clopidogrel. The patient became asymptomatic and ECG showed baseline rhythm after 1 week of stoppage of ticagrelor.
ISSN:	0976-500X 0976-5018
DOI:	10.4103/jpp.JPP_121_19