Search Results - "Anand, Swadha"

Diet, Microbiota and Gut-Lung Connection by Anand, Swadha, Mande, Sharmila S

“…The gut microbial community (Gut microbiota) is known to impact metabolic functions as well as immune responses in our body. Diet plays an important role in…”
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Comparative In silico Analysis of Butyrate Production Pathways in Gut Commensals and Pathogens by Anand, Swadha, Kaur, Harrisham, Mande, Sharmila S

“…Biosynthesis of butyrate by commensal bacteria plays a crucial role in maintenance of human gut health while dysbiosis in gut microbiome has been linked to…”
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Host-microbiome interactions: Gut-Liver axis and its connection with other organs by Anand, Swadha, Mande, Sharmila S.

“…An understanding of connections between gut microbiome and liver has provided important insights into the pathophysiology of liver diseases. Since gut…”
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SBSPKS: structure based sequence analysis of polyketide synthases by Anand, Swadha, Prasad, M.V.R, Yadav, Gitanjali, Kumar, Narendra, Shehara, Jyoti, Ansari, Md. Zeeshan, Mohanty, Debasisa

“…Polyketide synthases (PKSs) catalyze biosynthesis of a diverse family of pharmaceutically important secondary metabolites. Bioinformatics analysis of sequence…”
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In silico methods for linking genes and secondary metabolites: The way forward by Khater, Shradha, Anand, Swadha, Mohanty, Debasisa

“…In silico methods for linking genomic space to chemical space have played a crucial role in genomics driven discovery of new natural products as well as…”
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Corrigendum: FLIM-MAP: Gene Context Based Identification of Functional Modules in Bacterial Metabolic Pathways by Bhatt, Vineet, Mohapatra, Anwesha, Anand, Swadha, Kuntal, Bhusan K, Mande, Sharmila S

“…[This corrects the article DOI: 10.3389/fmicb.2018.02183.]…”
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FLIM-MAP: Gene Context Based Identification of Functional Modules in Bacterial Metabolic Pathways by Bhatt, Vineet, Mohapatra, Anwesha, Anand, Swadha, Kuntal, Bhusan K, Mande, Sharmila S

“…Prediction of functional potential of bacteria can only be ascertained by the accurate annotation of its metabolic pathways. Homology based methods decipher…”
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Functional Potential of Bacterial Communities using Gene Context Information by Mohapatra, Anwesha, Bhatt, Vineet, Anand, Swadha, Bhusan, Kuntal K., Mande, Sharmila S.

“…Abstract only…”
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Novel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase by Chopra, Tarun, Banerjee, Srijita, Gupta, Sarika, Yadav, Gitanjali, Anand, Swadha, Surolia, Avadhesha, Roy, Rajendra P, Mohanty, Debasisa, Gokhale, Rajesh S

“…In recent years, remarkable versatility of polyketide synthases (PKSs) has been recognized; both in terms of their structural and functional organization as…”
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‘GutFeel’: an in silico method for predicting gut health status based on the metabolic functional capabilities of the resident microbiome by Anand, Swadha, Bose, Chandrani, Kaur, Harrisham, Mande, Sharmila S.

“…Dysbiosis or imbalance in the gut microbiome has been correlated with the etiology of a number of diseases/disorders. Thus, gut microbial communities can…”
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FunGeCo: a web-based tool for estimation of functional potential of bacterial genomes and microbiomes using gene context information by Anand, Swadha, Kuntal, Bhusan K, Mohapatra, Anwesha, Bhatt, Vineet, Mande, Sharmila S

“…Abstract Motivation Functional potential of genomes and metagenomes which are inferred using homology-based methods are often subjected to certain limitations,…”
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Modeling holo-ACP:DH and holo-ACP:KR complexes of modular polyketide synthases: a docking and molecular dynamics study by Anand, Swadha, Mohanty, Debasisa

“…Modular polyketide synthases are multifunctional megasynthases which biosynthesize a variety of secondary metabolites using various combinations of dehydratase…”
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Inter-domain movements in polyketide synthases: a molecular dynamics study by Anand, Swadha, Mohanty, Debasisa

“…Insights into the structure and dynamics of modular polyketide synthases (PKS) are essential for understanding the mechanistic details of the biosynthesis of a…”
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Polyvalent Proteins, a Pervasive Theme in the Intergenomic Biological Conflicts of Bacteriophages and Conjugative Elements by Iyer, Lakshminarayan M, Burroughs, A Maxwell, Anand, Swadha, de Souza, Robson F, Aravind, L

“…Intense biological conflicts between prokaryotic genomes and their genomic parasites have resulted in an arms race in terms of the molecular "weaponry"…”
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Novel autoproteolytic and DNA-damage sensing components in the bacterial SOS response and oxidized methylcytosine-induced eukaryotic DNA demethylation systems by Aravind, L, Anand, Swadha, Iyer, Lakshminarayan M

“…The bacterial SOS response is an elaborate program for DNA repair, cell cycle regulation and adaptive mutagenesis under stress conditions. Using sensitive…”
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The natural history of ADP-ribosyltransferases and the ADP-ribosylation system by Aravind, L, Zhang, Dapeng, de Souza, Robson F, Anand, Swadha, Iyer, Lakshminarayan M

“…Catalysis of NAD(+)-dependent ADP-ribosylation of proteins, nucleic acids, or small molecules has evolved in at least three structurally unrelated…”
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Probing the amino acids critical for protein oligomerisation and protein–nucleotide interaction in Mycobacterium tuberculosis PII protein through integration of computational and experimental approaches by Jain, Sriyans, Mandal, Rahul Shubhra, Anand, Swadha, Maiti, Souvik, Ramachandran, Srinivasan

“…We investigated the interacting amino acids critical for the stability and ATP binding of Mycobacterium tuberculosis PII protein through a series of site…”
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Prediction of inter domain interactions in modular polyketide synthases by docking and correlated mutation analysis by Yadav, Gitanjali, Anand, Swadha, Mohanty, Debasisa

“…Polyketide synthases (PKSs) are huge multi-enzymatic protein complexes involved in the biosynthesis of one of the largest families of bioactive natural…”
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Genetic, biosynthetic and functional versatility of polyketide synthases by Nair, Divya R., Anand, Swadha, Verma, Priyanka, Mohanty, Debasisa, Gokhale, Rajesh S.

“…Polyketide synthases (PKSs) are multi-functional enzymes that exhibit a great deal of diversity in their biosynthetic mechanism. This versatility allows them…”
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