Search Results - "Anand, Priya"
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CancerPPD: a database of anticancer peptides and proteins
Published in Nucleic acids research (28-01-2015)“…CancerPPD (http://crdd.osdd.net/raghava/cancerppd/) is a repository of experimentally verified anticancer peptides (ACPs) and anticancer proteins. Data were…”
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PEPlife: A Repository of the Half-life of Peptides
Published in Scientific reports (07-11-2016)“…Short half-life is one of the key challenges in the field of therapeutic peptides. Various studies have reported enhancement in the stability of peptides using…”
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Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals
Published in mBio (16-10-2020)“…In the absence of effective vaccines and with limited therapeutic options, convalescent plasma is being collected across the globe for potential transfusion to…”
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Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles
Published in Cell host & microbe (09-12-2020)“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) mediates viral entry into cells and is critical for vaccine development against…”
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Prognostic Value of PET Myocardial Perfusion Imaging in Obese Patients
Published in JACC. Cardiovascular imaging (01-03-2014)“…Objectives This study sought to determine and compare the prognostic and incremental value of positron emission tomography (PET) in normal, overweight, and…”
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Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern
Published in Cell reports (Cambridge) (11-01-2022)“…Emerging variants of concern for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can transmit more efficiently and partially evade protective…”
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Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike
Published in Cell reports. Medicine (20-10-2020)“…SARS-CoV-2 is responsible for the coronavirus disease 2019 (COVID-19) pandemic, infecting millions of people and causing hundreds of thousands of deaths. The…”
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Deficiency in the endocytic adaptor proteins PHETA1/2 impairs renal and craniofacial development
Published in Disease models & mechanisms (26-05-2020)“…A critical barrier in the treatment of endosomal and lysosomal diseases is the lack of understanding of the functions of the putative causative genes. We…”
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Longitudinal analysis of humoral immunity against SARS-CoV-2 Spike in convalescent individuals up to 8 months post-symptom onset
Published in Cell reports. Medicine (15-06-2021)“…With the recent approval of highly effective coronavirus disease 2019 (COVID-19) vaccines, functional and lasting immunity to severe acute respiratory syndrome…”
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Two Families of Env Antibodies Efficiently Engage Fc-Gamma Receptors and Eliminate HIV-1-Infected Cells
Published in Journal of virology (01-02-2019)“…HIV-1 conceals epitopes of its envelope glycoproteins (Env) recognized by antibody (Ab)-dependent cellular cytotoxicity (ADCC)-mediating antibodies. These Abs,…”
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Antibody-Induced Internalization of HIV-1 Env Proteins Limits Surface Expression of the Closed Conformation of Env
Published in Journal of virology (01-06-2019)“…To minimize immune responses against infected cells, HIV-1 limits the surface expression of its envelope glycoprotein (Env). Here, we demonstrate that this…”
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High‐throughput detection of antibodies targeting the SARS‐CoV‐2 Spike in longitudinal convalescent plasma samples
Published in Transfusion (Philadelphia, Pa.) (01-05-2021)“…Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) virus is the cause of the ongoing coronavirus disease 2019 (COVID‐19) pandemic,…”
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Evolution of Anti-RBD IgG Avidity following SARS-CoV-2 Infection
Published in Viruses (04-03-2022)“…SARS-CoV-2 infection rapidly elicits anti-Spike antibodies whose quantity in plasma gradually declines upon resolution of symptoms. This decline is part of the…”
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Interaction of Human ACE2 to Membrane-Bound SARS-CoV-1 and SARS-CoV-2 S Glycoproteins
Published in Viruses (29-09-2020)“…Severe acute respiratory syndrome virus 2 (SARS-CoV-2) is responsible for the current global coronavirus disease 2019 (COVID-19) pandemic, infecting millions…”
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Understudied Factors Influencing Fc-Mediated Immune Responses against Viral Infections
Published in Vaccines (Basel) (30-08-2019)“…Antibodies play a crucial role in host defense against viruses, both by preventing infection and by controlling viral replication. Besides their capacity to…”
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Temsavir Treatment of HIV-1-Infected Cells Decreases Envelope Glycoprotein Recognition by Broadly Neutralizing Antibodies
Published in mBio (28-06-2022)“…The heavily glycosylated HIV-1 envelope glycoprotein (Env) is the sole viral antigen present at the surface of virions and infected cells, representing the…”
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SARS-CoV-2 Spike Expression at the Surface of Infected Primary Human Airway Epithelial Cells
Published in Viruses (21-12-2021)“…Different serological assays were rapidly generated to study humoral responses against the SARS-CoV-2 Spike glycoprotein. Due to the intrinsic difficulty of…”
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Estimating public health risks of infectious disease events: A Canadian approach to rapid risk assessment
Published in Canada communicable disease report (01-09-2024)“…The COVID-19 pandemic highlighted the need for timely, evidence-based rapid risk assessments (RRA) of infectious disease events to inform public health action…”
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HIV-1 Envelope Glycoprotein Cell Surface Localization Is Associated with Antibody-Induced Internalization
Published in Viruses (29-09-2021)“…To minimize immune responses against infected cells, HIV-1 has evolved different mechanisms to limit the surface expression of its envelope glycoproteins…”
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Evaluating Humoral Immunity against SARS-CoV-2: Validation of a Plaque-Reduction Neutralization Test and a Multilaboratory Comparison of Conventional and Surrogate Neutralization Assays
Published in Microbiology spectrum (22-12-2021)“…The evaluation of humoral protective immunity against SARS-CoV-2 remains crucial in understanding both natural immunity and protective immunity conferred by…”
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