Search Results - "Anan, Intissar"

Structural basis for transthyretin amyloid formation in vitreous body of the eye by Iakovleva, Irina, Hall, Michael, Oelker, Melanie, Sandblad, Linda, Anan, Intissar, Sauer-Eriksson, A. Elisabeth

“…Amyloid transthyretin (ATTR) amyloidosis is characterized by the abnormal accumulation of ATTR fibrils in multiple organs. However, the structure of ATTR…”
Get full text

Enlarged cross-sectional area in peripheral nerves in Swedish patients with hereditary V30M transthyretin amyloidosis by Arvidsson, Sandra, Eriksson, Robert, Anan, Intissar, Heldestad, Victoria

“…INTRODUCTIONIn hereditary transthyretin amyloidosis (ATTRv), two different fibrillar forms causing the amyloid deposition, have been identified, displaying…”
Get full text

Amyloid fibril composition within hereditary Val30Met (p. Val50Met) transthyretin amyloidosis families by Suhr, Ole Bernt, Wixner, Jonas, Anan, Intissar, Lundgren, Hans-Erik, Wijayatunga, Priyantha, Westermark, Per, Ihse, Elisabet

“…The amyloid fibril in hereditary transthyretin (TTR) Val30Met (pVal50Met) amyloid (ATTR Val30Met) amyloidosis is composed of either a mixture of full-length…”
Get full text

Abdominal fat pad biopsies exhibit good diagnostic accuracy in patients with suspected transthyretin amyloidosis by Paulsson Rokke, Hedvig, Sadat Gousheh, Nima, Westermark, Per, Suhr, Ole B, Anan, Intissar, Ihse, Elisabet, Pilebro, Björn, Wixner, Jonas

“…Abstract Background The diagnostic accuracy of histopathological detection of transthyretin amyloid (ATTR) by Congo red staining of abdominal fat samples has…”
Get full text

Amyloid fibril composition type is consistent over time in patients with Val30Met (p.Val50Met) transthyretin amyloidosis by Anan, Intissar, Suhr, Ole B, Liszewska, Katarzyna, Mejia Baranda, Jorge, Pilebro, Björn, Wixner, Jonas, Ihse, Elisabet

“…We have previously shown that transthyretin (TTR) amyloidosis patients have amyloid fibrils of either of two compositions; type A fibrils consisting of large…”
Get full text

THAOS: gastrointestinal manifestations of transthyretin amyloidosis - common complications of a rare disease by Wixner, Jonas, Mundayat, Rajiv, Karayal, Onur N, Anan, Intissar, Karling, Pontus, Suhr, Ole B

“…Transthyretin amyloidosis is a systemic disorder caused by amyloid deposits formed by misfolded transthyretin monomers. Two main forms exist: hereditary and…”
Get full text

Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma by Iakovleva, Irina, Brännström, Kristoffer, Nilsson, Lina, Gharibyan, Anna L, Begum, Afshan, Anan, Intissar, Walfridsson, Malin, Sauer-Eriksson, A. Elisabeth, Olofsson, Anders

“…The plasma protein transthyretin (TTR) is linked to human amyloidosis. Dissociation of its native tetrameric assembly is a rate-limiting step in the conversion…”
Get full text

Combining ECG and echocardiography to identify transthyretin cardiac amyloidosis in heart failure by Löfbacka, Viktor, Suhr, Ole B., Pilebro, Bjorn, Wixner, Jonas, Sundström, Torbjorn, Lindmark, Krister, Anan, Intissar, Lindqvist, Per

“…Aims/background Transthyretin amyloid (ATTR) amyloidosis cardiomyopathy is an underdiagnosed, causatively treatable cause of heart failure (HF). The aim of…”
Get full text

Atrial Fibrillation and Central Nervous Complications in Liver Transplanted Hereditary Transthyretin Amyloidosis Patients by Wange, Niklas, Anan, Intissar, Ericzon, Bo-Göran, Pennlert, Johanna, Pilebro, Björn, Suhr, Ole B, Wixner, Jonas

“…BACKGROUNDCentral nervous system (CNS) complications are increasingly noted in liver transplanted (LTx) hereditary transthyretin amyloid (ATTRm) amyloidosis…”
Get full text

Endogenous Human Proteins Interfering with Amyloid Formation by Gharibyan, Anna L, Wasana Jayaweera, Sanduni, Lehmann, Manuela, Anan, Intissar, Olofsson, Anders

“…Amyloid formation is a pathological process associated with a wide range of degenerative disorders, including Alzheimer's disease, Parkinson's disease, and…”
Get full text

Cerebellar and Cerebral Amyloid Visualized by [ 18 F]flutemetamol PET in Long-Term Hereditary V30M ( p.V50M ) Transthyretin Amyloidosis Survivors by Uneus, Erica Irene, Wilhelmsson, Christer, Bäckström, David, Anan, Intissar, Wixner, Jonas, Pilebro, Björn, Riklund, Katrine, Ögren, Mattias, Ögreen, Margareta, Axelsson, Jan, Suhr, Ole B, Sundström, Torbjörn

“…Hereditary transthyretin (ATTRv) amyloidosis caused by the V30M ( ) mutation is a fatal, neuropathic systemic amyloidosis. Liver transplantation has prolonged…”
Get full text

Mechanisms of Transthyretin Inhibition of IAPP Amyloid Formation by Wasana Jayaweera, Sanduni, Surano, Solmaz, Pettersson, Nina, Oskarsson, Elvira, Lettius, Lovisa, Gharibyan, Anna L, Anan, Intissar, Olofsson, Anders

“…Amyloid-formation by the islet amyloid polypeptide (IAPP), produced by the β-cells in the human pancreas, has been associated with the development of type II…”
Get full text

Impact of serotonin transporter and catechol- O-methyl transferase genes polymorphism on gastrointestinal dysfunction in Swedish and Japanese familial amyloidotic polyneuropathy patients by Obayashi, Konen, Olsson, Malin, Anan, Intissar, Ueda, Mitsuharu, Nakamura, Masaaki, Okamoto, Sadahisa, Yamashita, Taro, Miida, Takashi, Ando, Yukio, Suhr, Ole B.

“…Differences in the gastrointestinal manifestations have emerged between Swedish and Japanese familial amyloidotic polyneuropathy amyloidogenic transthyretin…”
Get full text

N°159 – Ultrasonography of peripheral nerves in Swedish patients with hereditary transthyretin amyloidosis by Heldestad, Victoria, Eriksson, Robert, Anan, Intissar, Arvidsson, Sandra

Get full text

Anti-PEG antibodies associated with reduced therapeutic effect of patisiran in patients with hereditary transthyretin amyloidosis by Pilebro, Björn, Wixner, Jonas, Anan, Intissar

Get full text

Metabolomics analysis for diagnosis and biomarker discovery of transthyretin amyloidosis by Olsson, Malin, Hellman, Urban, Wixner, Jonas, Anan, Intissar

“…Untargeted metabolomics is a well-established technique and a powerful tool to find potential plasma biomarkers for early diagnosing hereditary transthyretin…”
Get full text

Amyloid fibril composition type is consistent over time in patients with Val30Met by Anan, Intissar, Suhr, Ole B, Liszewska, Katarzyna, Mejia Baranda, Jorge, Pilebro, Björn, Wixner, Jonas, Ihse, Elisabet

“…Background We have previously shown that transthyretin (TTR) amyloidosis patients have amyloid fibrils of either of two compositions; type A fibrils consisting…”
Get full text

New data on the genetic profile and penetrance of hereditary Val30Met transthyretin amyloidosis in Sweden by Gorram, Farida, Olsson, Malin, Alarcon, Flora, Nuel, Gregory, Anan, Intissar, Planté-Bordeneuve, Violaine

“…Hereditary transthyretin (ATTRv) amyloidosis is of autosomal dominant transmission, caused by a spectrum of mutations in the transthyretin (TTR) gene. The…”
Get full text

Cardiomyopathy in Swedish patients with the Gly53Glu and His88Arg transthyretin variants by Holmgren, Gösta, Hellman, Urban, Anan, Intissar, Lundgren, Hans-Eric, Jonasson, Jenni, Stafberg, Christina, Fahoum, Sämi, Suhr, Ole B.

“…We report two new amyloidogenic transthyretin (TTR) variants detected in the Swedish population. One variant was previously unknown, while the other has been…”
Get full text

Comparison of amyloid deposits and infiltration of enteric nervous system in the upper with those in the lower gastrointestinal tract in patients with familial amyloidotic polyneuropathy by ANAN, Intissar, EL-SALHY, Magdy, ANDO, Yukio, TERAZAKI, Hisayasu, SUHR, Ole B

“…Gastrointestinal (GI) complications in familial amyloidotic polyneuropathy (FAP) are invariably present during the course of the disease. The aim of this study…”
Get full text