Search Results - "Anakor, Ekene"
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Perioperative Heart-Brain Axis Protection in Obese Surgical Patients: The Nutrigenomic Approach
Published in Current medicinal chemistry (2020)“…The number of obese patients undergoing cardiac and noncardiac surgery is rapidly increasing because they are more prone to concomitant diseases, such as…”
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Journal Article -
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Molecular and Cellular Mechanisms Affected in ALS
Published in Journal of personalized medicine (01-09-2020)“…Amyotrophic lateral sclerosis (ALS) is a terminal late-onset condition characterized by the loss of upper and lower motor neurons. Mutations in more than 30…”
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Journal Article -
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Exosomes in Ageing and Motor Neurone Disease: Biogenesis, Uptake Mechanisms, Modifications in Disease and Uses in the Development of Biomarkers and Therapeutics
Published in Cells (Basel, Switzerland) (28-10-2021)“…Intercellular communication between neurons and their surrounding cells occurs through the secretion of soluble molecules or release of vesicles such as…”
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Optimized method for extraction of exosomes from human primary muscle cells
Published in Skeletal muscle (08-07-2020)“…Abstract Skeletal muscle is increasingly considered an endocrine organ secreting myokines and extracellular vesicles (exosomes and microvesicles), which can…”
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The Neurotoxicity of Vesicles Secreted by ALS Patient Myotubes Is Specific to Exosome-Like and Not Larger Subtypes
Published in Cells (Basel, Switzerland) (01-03-2022)“…Extracellular vesicles can mediate communication between tissues, affecting the physiological conditions of recipient cells. They are increasingly investigated…”
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The Cellular and Molecular Signature of ALS in Muscle
Published in Journal of personalized medicine (08-11-2022)“…Amyotrophic lateral sclerosis is a disease affecting upper and lower motor neurons. Although motor neuron death is the core event of ALS pathology, it is…”
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Neurotoxicity of Skeletal Muscle Extracellular Vesicles in Amyotrophic Lateral Sclerosis (Als) : Vesicle Sub-Type Specificity, Target Cell Type Specificity, and Mechanisms of Uptake
Published 01-01-2022“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative and multi-system disease characterised by the gradual degeneration and loss of upper and lower motor…”
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Dissertation -
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Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles
Published in Journal of cachexia, sarcopenia and muscle (01-04-2022)“…Background The cause of the motor neuron (MN) death that drives terminal pathology in amyotrophic lateral sclerosis (ALS) remains unknown, and it is thought…”
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Journal Article -
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Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles
Published in Journal of cachexia, sarcopenia and muscle (22-02-2022)“…Background: The cause of the motor neuron (MN) death that drives terminal pathology in amyotrophic lateral sclerosis (ALS) remains unknown, and it is thought…”
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Journal Article