Search Results - "Anakha, J."
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Treating liver cancer through arginine depletion
Published in Drug discovery today (01-04-2024)“…•Liver cancer, a global threat, ranks sixth in incidence and is the second-leading cause of cancer fatalities.•Despite effective treatments, issues like…”
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Towards development of biobetter: L-asparaginase a case study
Published in Biochimica et biophysica acta. General subjects (01-01-2024)“…L-asparaginase (ASNase) has played a key role in the management of acute lymphoblastic leukaemia (ALL). As an amidohydrolase, it catalyzes the hydrolysis of…”
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Broad-spectrum anti-cancer activity of fused human arginase variants
Published in Investigational new drugs (20-08-2024)“…The rapid increase in cancer cases worldwide necessitates the development of novel therapeutic approaches. Therapies targeting cancer's altered metabolism,…”
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Recombinant human endostatin as a potential anti-angiogenic agent: therapeutic perspective and current status
Published in Medical oncology (Northwood, London, England) (21-12-2023)“…Angiogenesis is the physiological process that results in the formation of new blood vessels develop from pre-existing vasculature and plays a significant role…”
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Development and characterization of fused human arginase I for cancer therapy
Published in Investigational new drugs (01-10-2023)“…Recombinant human arginase I (rhArg I) have emerged as a potential candidate for the treatment of varied pathophysiological conditions ranging from…”
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Understanding defect chemistry in TMOS involved electrocatalytic OER; an analysis for advancement
Published in Surfaces and interfaces (01-06-2022)“…The huge requirement of oxygen in the current pandemic situation highlights the urgency of industrially relevant electrocatalytic oxygen evolution reaction and…”
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Human arginase I: a potential broad-spectrum anti-cancer agent
Published in 3 Biotech (01-05-2023)“…With high rates of morbidity and mortality, cancer continues to pose a serious threat to public health on a global scale. Considering the discrepancies in…”
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Human arginase 1, a Jack of all trades?
Published in 3 Biotech (01-10-2022)“…Arginine, a conditionally essential amino acid, plays a crucial role in several metabolic and signalling pathways. Arginine metabolism in the body can be…”
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