Search Results - "Anaclerio, Beth"

Design, synthesis, and biological evaluations of novel quinolones as HIV-1 non-nucleoside reverse transcriptase inhibitors by Ellis, David, Kuhen, Kelli L., Anaclerio, Beth, Wu, Baogen, Wolff, Karen, Yin, Hong, Bursulaya, Badry, Caldwell, Jeremy, Karanewsky, Donald, He, Yun

“…A novel series of quinolones was discovered as HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) using a structure-based approach. The lead…”
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Design, Synthesis, and Biological Evaluation of Novel Potent and Selective αvβ3/αvβ5 Integrin Dual Inhibitors with Improved Bioavailability. Selection of the Molecular Core by Marugán, Juan José, Manthey, Carl, Anaclerio, Beth, Lafrance, Lou, Lu, Tianbao, Markotan, Tom, Leonard, Kristi A, Crysler, Carl, Eisennagel, Stephen, Dasgupta, Malini, Tomczuk, Bruce

“…A novel series of potent and selective αvβ3/αvβ5 dualinhibitors was designed, synthesized, and evaluated against several integrins. These compounds were…”
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Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1 by Wu, Baogen, Kuhen, Kelli, Ngoc Nguyen, Truc, Ellis, David, Anaclerio, Beth, He, Xiaohui, Yang, Kunyong, Karanewsky, Donald, Yin, Hong, Wolff, Karen, Bieza, Kimberly, Caldwell, Jeremy, He, Yun

“…N-Aryl pyrrolidinones as novel anti-HIV-1 agents is reported. The synthesis and preliminary structure–activity relationship of a series of pyrrolidinones are…”
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Non-peptidic αvβ3 antagonists containing indol-1-yl propionic acids by Leonard, Kristi, Pan, Wenxi, Anaclerio, Beth, Gushue, Joan M., Guo, Zihong, DesJarlais, Renee L., Chaikin, Marge A., Lattanze, Jennifer, Crysler, Carl, Manthey, Carl L., Tomczuk, Bruce E., Marugan, Juan Jose

“…[Display omitted] We describe the synthesis and structure/activity relationship of RGD mimetics that are potent inhibitors of the integrin αvβ3. Indol-1-yl…”
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Design, synthesis, and biological evaluation of novel potent and selective alphavbeta3/alphavbeta5 integrin dual inhibitors with improved bioavailability. Selection of the molecular core by Marugán, Juan José, Manthey, Carl, Anaclerio, Beth, Lafrance, Lou, Lu, Tianbao, Markotan, Tom, Leonard, Kristi A, Crysler, Carl, Eisennagel, Stephen, Dasgupta, Malini, Tomczuk, Bruce

“…A novel series of potent and selective alpha(v)beta(3)/alpha(v)beta(5) dual( )()inhibitors was designed, synthesized, and evaluated against several integrins…”
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Design, Synthesis, and Biological Evaluation of Novel Potent and Selective α v β 3 /α v β 5 Integrin Dual Inhibitors with Improved Bioavailability. Selection of the Molecular Core by Marugán, Juan José, Manthey, Carl, Anaclerio, Beth, Lafrance, Lou, Lu, Tianbao, Markotan, Tom, Leonard, Kristi A., Crysler, Carl, Eisennagel, Stephen, Dasgupta, Malini, Tomczuk, Bruce

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Non-peptidic alpha(v)beta3 antagonists containing indol-1-yl propionic acids by Leonard, Kristi, Pan, Wenxi, Anaclerio, Beth, Gushue, Joan M, Guo, Zihong, DesJarlais, Renee L, Chaikin, Marge A, Lattanze, Jennifer, Crysler, Carl, Manthey, Carl L, Tomczuk, Bruce E, Marugan, Juan Jose

“…We describe the synthesis and structure/activity relationship of RGD mimetics that are potent inhibitors of the integrin alpha(v)beta3. Indol-1-yl propionic…”
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Cyclobutane carboxamide inhibitors of fungal melanin : Biosynthesis and their evaluation as fungicides by JENNINGS, L. D, RAYNER, D. R, JORDAN, D. B, OKONYA, J. F, BASARAB, G. S, AMOROSE, D. K, ANACLERIO, B. M, LEE, J. K, SCHWARTZ, R. S, WHITMORE, K. A

“…A new fungicide lead has been identified by enzyme screening of a focused combinatorial library. The lead compound 4, a potent inhibitor of scytalone…”
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New one-pot method for the synthesis of alkynyl sulfonate esters using ultrasound by Tuncay, Atilla, Anaclerio, Beth M., Zolodz, Melissa, Suslick, Kenneth S.

“…A new one-pot method for the preparation of alkynyl sulfonate esters from terminal alkynes is reported. A metal-assisted, ultrasound-enhanced nucleophilic…”
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A functional radioreceptor assay of alpha-V-beta-3 (α vβ 3) inhibitors in plasma: Application as an ex vivo pharmacodynamic model by Chaikin, Margery A., Marugan, Júan José, De Vries, Gerald W., Baciu, Peter, Edelman, Jeffrey, Ni, Ming, Tomczuk, Bruce E., Pan, Wenxi, Guo, Zihong, Anaclerio, Beth, Leonard, Kristi, Eisennagel, Stephen H., Molloy, Christopher J., Manthey, Carl L.

“…Development of α vβ 3-integrin inhibitors has been hampered by a lack of pharmacodynamic endpoints to identify doses that inhibit α vβ 3 in vivo. To address…”
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