Search Results - "Ana Patiño-García"

Wnt signaling and Loxl2 promote aggressive osteosarcoma by Matsuoka, Kazuhiko, Bakiri, Latifa, Wolff, Lena I., Linder, Markus, Mikels-Vigdal, Amanda, Patiño-García, Ana, Lecanda, Fernando, Hartmann, Christine, Sibilia, Maria, Wagner, Erwin F.

“…Osteosarcoma (OS) is the most frequent primary malignant bone tumor in urgent need of better therapies. Using genetically modified mouse models (GEMMs), we…”
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Primary trimethylaminuria syndrome: more than an unpleasant odor by Antoñanzas, Javier, Querol‐Cisneros, Elena, Alkorta‐Aranburu, Gorka, Patiño‐García, Ana, España, Agustín

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Identification of mutations associated with acquired resistance to sunitinib in renal cell cancer by Elgendy, Mohamed, Fusco, Juan Pablo, Segura, Victor, Lozano, Maria Dolores, Minucci, Saverio, Echeveste, Jose Ignacio, Gurpide, Alfonso, Andueza, Mapi, Melero, Ignacio, Sanmamed, Miguel F., Ruiz, Maria Rodriguez, Calvo, Alfonso, Pascual, Juan Ignacio, Velis, Jose María, Miñana, Bernardino, Valle, Ricardo Diez, Pio, Ruben, Agorreta, Jackeline, Abengozar, Marta, Colecchia, Maurizio, Brich, Silvia, Renne, Salvatore Lorenzo, Guruceaga, Elisabet, Patiño‐García, Ana, Perez‐Gracia, Jose Luis

“…Sunitinib is one of the most widely used targeted therapeutics for renal cell carcinoma (RCC), but acquired resistance against targeted therapies remains a…”
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Identification of germline cancer predisposition variants in pediatric sarcoma patients from somatic tumor testing by Alba-Pavón, Piedad, Alaña, Lide, Gutierrez-Jimeno, Miriam, García-Obregón, Susana, Imízcoz, Teresa, Panizo, Elena, González-Urdiales, Paula, Echebarria-Barona, Aizpea, Lopez Almaraz, Ricardo, Zaldumbide, Laura, Astigarraga, Itziar, Patiño-García, Ana, Villate, Olatz

“…Genetic predisposition is an important risk factor for cancer in children and adolescents but detailed associations of individual genetic mutations to…”
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Matrix-Gla protein promotes osteosarcoma lung metastasis and associates with poor prognosis by Zandueta, Carolina, Ormazábal, Cristina, Perurena, Naiara, Martínez-Canarias, Susana, Zalacaín, Marta, Julián, Mikel San, Grigoriadis, Agamemnon E, Valencia, Karmele, Campos-Laborie, Francisco J, Rivas, Javier De Las, Vicent, Silvestre, Patiño-García, Ana, Lecanda, Fernando

“…Osteosarcoma (OS) is the most prevalent osseous tumour in children and adolescents and, within this, lung metastases remain one of the factors associated with…”
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Characterization of the Antiglioma Effect of the Oncolytic Adenovirus VCN-01 by Vera, Beatriz, Martínez-Vélez, Naiara, Xipell, Enric, Acanda de la Rocha, Arlet, Patiño-García, Ana, Saez-Castresana, Javier, Gonzalez-Huarriz, Marisol, Cascallo, Manel, Alemany, Ramón, Alonso, Marta M

“…Despite the recent advances in the development of antitumor therapies, the prognosis for patients with malignant gliomas remains dismal. Therapy with…”
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Methotrexate in Pediatric Osteosarcoma: Response and Toxicity in Relation to Genetic Polymorphisms and Dihydrofolate Reductase and Reduced Folate Carrier 1 Expression by Patiño-García, Ana, PhD, Zalacaín, Marta, PhD, Marrodán, Lucía, BSc, San-Julián, Mikel, MD, PhD, Sierrasesúmaga, Luis, MD, PhD

“…Objective To determine the influence of the genotype and the level of expression of different enzymes involved in folate metabolism on the response to and…”
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DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report by Tejada, Sonia, Díez-Valle, Ricardo, Domínguez, Pablo D, Patiño-García, Ana, González-Huarriz, Marisol, Fueyo, Juan, Gomez-Manzano, Cande, Idoate, Miguel Angel, Peterkin, Joanna, Alonso, Marta M

“…Diffuse intrinsic pontine gliomas (DIPGs) are aggressive glial brain tumors that primarily affect children, for which there is no curative treatment. Median…”
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Antitumoral-Lipid-Based Nanoparticles: a Platform for Future Application in Osteosarcoma therapy by González-Fernández, Yolanda, Imbuluzqueta, Edurne, Patiño-García, Ana, Blanco-Prieto, María J

“…Osteosarcoma is the most frequent primary bone tumor in the pediatric age group. Its aggressive local growth pattern and its high propensity to metastasize,…”
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FHL2 silencing reduces Wnt signaling and osteosarcoma tumorigenesis in vitro and in vivo by Brun, Julia, Dieudonné, François-Xavier, Marty, Caroline, Müller, Judith, Schüle, Roland, Patiño-García, Ana, Lecanda, Fernando, Fromigué, Olivia, Marie, Pierre J

“…The molecular mechanisms that are involved in the growth and invasiveness of osteosarcoma, an aggressive and invasive primary bone tumor, are not fully…”
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Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models by Martinez-Velez, Naiara, Marigil, Miguel, García-Moure, Marc, Gonzalez-Huarriz, Marisol, Aristu, Jose Javier, Ramos-García, Luis-Isaac, Tejada, Sonia, Díez-Valle, Ricardo, Patiño-García, Ana, Becher, Oren J, Gomez-Manzano, Candelaria, Fueyo, Juan, Alonso, Marta M

“…Pediatric high grade gliomas (pHGG), including diffuse intrinsic pontine gliomas (DIPGs), are aggressive tumors with a dismal outcome. Radiotherapy (RT) is…”
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Assessment of metabolic patterns and new antitumoral treatment in osteosarcoma xenograft models by [ 18 F]FDG and sodium [ 18 F]fluoride PET by Collantes, María, Martínez-Vélez, Naiara, Zalacain, Marta, Marrodán, Lucia, Ecay, Margarita, García-Velloso, María José, Alonso, Marta María, Patiño-García, Ana, Peñuelas, Iván

“…Osteosarcoma is the most common malignant bone tumor in children and young adults that produces aberrant osteoid. The aim of this study was to assess the…”
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Development of a DIPG Orthotopic Model in Mice Using an Implantable Guide-Screw System by Marigil, Miguel, Martinez-Velez, Naiara, Domínguez, Pablo D, Idoate, Miguel Angel, Xipell, Enric, Patiño-García, Ana, Gonzalez-Huarriz, Marisol, García-Moure, Marc, Junier, Marie-Pierre, Chneiweiss, Hervé, El-Habr, Elías, Diez-Valle, Ricardo, Tejada-Solís, Sonia, Alonso, Marta M

“…In this work we set to develop and to validate a new in vivo frameless orthotopic Diffuse Intrinsic Pontine Glioma (DIPG) model based in the implantation of a…”
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Oncolytic adenoviruses as a therapeutic approach for osteosarcoma: A new hope by Garcia-Moure, Marc, Martinez-Vélez, Naiara, Patiño-García, Ana, Alonso, Marta M

“…Abstract Osteosarcoma is the most common bone cancer among those with non-hematological origin and affects mainly pediatric patients. In the last 50 years,…”
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Case Report: The Value of Genomic Analysis in a Case of Megakaryoblastic Leukemia With Atypical Initial Manifestation by Gutiérrez-Jimeno, Miriam, Panizo-Morgado, Elena, Calvo-Imirizaldu, Marta, Galán-Gómez, Víctor, Escudero-López, Adela, Patiño-García, Ana

“…We report the case of a 7-month-old female patient who developed acute megakaryoblastic leukemia 6 months after the appearance of skull bone lesions. Initial…”
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Correlation of myelodysplastic syndromes with i(17)(q10) and TP53 and SETBP1 mutations by Adema, Vera, Larráyoz, María J., Calasanz, María J., Palomo, Laura, Patiño‐García, Ana, Agirre, Xabier, Hernández‐Rivas, Jesús M., Lumbreras, Eva, Buño, Ismael, Martinez‐Laperche, Carolina, Mallo, Mar, García, Olga, Álvarez, Sara, Blazquez, Beatriz, Cervera, José, Luño, Elisa, Valiente, Alberto, Vallespí, María T., Arenillas, Leonor, Collado, Rosa, Pérez‐Oteyza, Jaime, Solé, Francesc

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Targeting the E3 ubiquitin casitas B-lineage lymphoma decreases osteosarcoma cell growth and survival and reduces tumorigenesis by Sévère, Nicolas, Dieudonné, François-Xavier, Marty, Caroline, Modrowski, Dominique, Patiño-García, Ana, Lecanda, Fernando, Fromigué, Olivia, Marie, Pierre J

“…Targeting receptor tyrosine kinase (RTK) degradation may be an interesting approach to reduce RTK cell signaling in cancer cells. Here we show that increasing…”
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Galectin-3 inhibition boosts the therapeutic efficacy of Semliki Forest virus in pediatric osteosarcoma by Herrador-Cañete, Guillermo, Zalacain, Marta, Labiano, Sara, Laspidea, Virginia, Puigdelloses, Montserrat, Marrodan, Lucía, Garcia-Moure, Marc, Gonzalez-Huarriz, Marisol, Marco-Sanz, Javier, Ausejo-Mauleon, Iker, de la Nava, Daniel, Hernández-Osuna, Reyes, Martínez-García, Javier, Silva-Pilipich, Noelia, Gurucega, Elisabeth, Patiño-García, Ana, Hernández-Alcoceba, Rubén, Smerdou, Cristian, Alonso, Marta M.

“…The outcomes of metastatic and nonresponder pediatric osteosarcoma patients are very poor and have not improved in the last 30 years. These tumors harbor a…”
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Local administration of IL-12 with an HC vector results in local and metastatic tumor control in pediatric osteosarcoma by Zalacain, Marta, Bunuales, María, Marrodan, Lucía, Labiano, Sara, Gonzalez-Huarriz, Marisol, Martinez-Vélez, Naiara, Laspidea, Virginia, Puigdelloses, Montse, García-Moure, Marc, Gonzalez-Aparicio, Manuela, Hernandez-Alcoceba, Rubén, Alonso, Marta M., Patiño-García, Ana

“…Osteosarcoma is the most frequent and aggressive bone tumor in children and adolescents, with a long-term survival rate of 30%. Interleukin-12 (IL-12) is a…”
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RNU6-1 in circulating exosomes differentiates GBM from non-neoplastic brain lesions and PCNSL but not from brain metastases by Puigdelloses, Montserrat, González-Huárriz, Marisol, García-Moure, Marc, Martínez-Vélez, Naiara, Esparragosa Vázquez, Inés, Bruna, Jordi, Zandio, Beatriz, Agirre, Amaia, Marigil, Miguel, Petrirena, Gregorio, Nuñez-Córdoba, Jorge M, Tejada-Solís, Sonia, Díez-Valle, Ricardo, Gállego-Culleré, Jaime, Martínez-Vila, Eduardo, Patiño-García, Ana, Alonso, Marta M, Gállego Pérez-Larraya, Jaime

“…Abstract Background Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. Circulating biomarkers may assist in the processes of…”
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