Search Results - "Ana Belén López-Rodríguez"
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Molecular Characterization of a Novel N-Acetylneuraminate Lyase from Lactobacillus plantarum WCFS1
Published in Applied and Environmental Microbiology (01-04-2011)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Synthesis and Pharmacological Evaluation of New N‑Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout
Published in Journal of medicinal chemistry (28-04-2022)“…NLRP3 is involved in the pathophysiology of several inflammatory diseases. Therefore, there is high current interest in the clinical development of new NLRP3…”
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Oxidative damage in reperfusion after stroke: ferroptosis and the role of the mitochondrial sodium/calcium exchanger NCLX
Published in Free radical biology & medicine (01-06-2024)Get full text
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New roles of mitochondrial Na+ import by the Na+/Ca2+ exchanger NCLX: activation of the HIF pathway and of the NLRP3 inflammasome
Published in Free radical biology & medicine (01-11-2023)Get full text
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New roles of mitochondrial Na+ import by the Na+/Ca2+ exchanger NCLX: activation of the HIF pathway and of the NLRP3 inflammasome
Published in Free radical biology & medicine (20-05-2023)Get full text
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Time‐dependent dual effect of NLRP3 inflammasome in brain ischaemia
Published in British journal of pharmacology (01-04-2022)“…Background Inflammasomes are cytosolic multiprotein complexes which, upon assembly, activate the maturation and secretion of the inflammatory cytokines IL‐1β…”
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The Endocannabinoid System as Pharmacological Target Derived from Its CNS Role in Energy Homeostasis and Reward. Applications in Eating Disorders and Addiction
Published in Pharmaceuticals (10-08-2011)“…The endocannabinoid system (ECS) has been implicated in many physiological functions, including the regulation of appetite, food intake and energy balance, a…”
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TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury
Published in British journal of pharmacology (01-09-2021)“…Background and Purpose Activation of astrocytes contributes to synaptic remodelling, tissue repair and neuronal survival following traumatic brain injury…”
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Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression
Published in Glia (01-07-2019)“…Type I interferons (IFN‐I) are the principal antiviral molecules of the innate immune system and can be made by most cell types, including central nervous…”
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Sex‐dependent long‐term effects of adolescent exposure to THC and/or MDMA on neuroinflammation and serotoninergic and cannabinoid systems in rats
Published in British journal of pharmacology (01-03-2014)“…Background and Purpose Many young people consume ecstasy as a recreational drug and often in combination with cannabis. In this study, we aimed to mimic human…”
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Blockage of neonatal leptin signaling induces changes in the hypothalamus associated with delayed pubertal onset and modifications in neuropeptide expression during adulthood in male rats
Published in Peptides (New York, N.Y. : 1980) (01-12-2016)“…•Blockage of leptin signaling neonatally delays pubertal onset in male rats.•Neonatal leptin antagonism increases serum leptin, insulin and triglycerides in…”
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Systemic TNF-α produces acute cognitive dysfunction and exaggerated sickness behavior when superimposed upon progressive neurodegeneration
Published in Brain, behavior, and immunity (01-01-2017)“…Graphical abstract…”
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Astrocytes: Heterogeneous and Dynamic Phenotypes in Neurodegeneration and Innate Immunity
Published in The Neuroscientist (01-10-2019)“…Astrocytes are the most numerous cell type in the brain and perform several essential functions in supporting neuronal metabolism and actively participating in…”
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Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL‐1β drives amplified responses in primed astrocytes and neuronal network dysfunction
Published in Alzheimer's & dementia (01-10-2021)“…Neuroinflammation contributes to Alzheimer's disease (AD) progression. Secondary inflammatory insults trigger delirium and can accelerate cognitive decline…”
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Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium
Published in The Journal of neuroscience (15-07-2020)“…Systemic infection triggers a spectrum of metabolic and behavioral changes, collectively termed sickness behavior, which while adaptive, can affect mood and…”
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Bath salts and polyconsumption: in search of drug-drug interactions
Published in Psychopharmacology (01-03-2019)“…Background and rationale Polydrug use is a widespread phenomenon, especially among adolescents and young adults. Synthetic cathinones are frequently consumed…”
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A comparative, developmental, and clinical perspective of neurobehavioral sexual dimorphisms
Published in Frontiers in neuroscience (01-01-2012)“…Women and men differ in a wide variety of behavioral traits and in their vulnerability to developing certain mental disorders. This review endeavors to explore…”
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Changes in cannabinoid receptors, aquaporin 4 and vimentin expression after traumatic brain injury in adolescent male mice. Association with edema and neurological deficit
Published in PloS one (03-06-2015)“…Traumatic brain injury (TBI) incidence rises during adolescence because during this critical neurodevelopmental period some risky behaviors increase. The…”
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Profiling Neuroactive Steroid Levels After Traumatic Brain Injury in Male Mice
Published in Endocrinology (Philadelphia) (01-10-2016)“…The incidence of traumatic brain injuries (TBIs) in humans has rapidly increased in the last ten years. The most common causes are falls and car accidents…”
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Correlation of brain levels of progesterone and dehydroepiandrosterone with neurological recovery after traumatic brain injury in female mice
Published in Psychoneuroendocrinology (01-06-2015)“…Highlights • Neuroactive steroid levels change in the brain after TBI. • Brain and plasma steroid levels vary differently and independently after TBI. • Brain…”
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