Search Results - "An, Jiyuan"

miRDeep: an integrated application tool for miRNA identification from RNA sequencing data by An, Jiyuan, Lai, John, Lehman, Melanie L, Nelson, Colleen C

“…miRDeep and its varieties are widely used to quantify known and novel micro RNA (miRNA) from small RNA sequencing (RNAseq). This article describes miRDeep*,…”
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Using Mendelian randomization to evaluate the causal relationship between serum C-reactive protein levels and age-related macular degeneration by Han, Xikun, Ong, Jue-Sheng, An, Jiyuan, Hewitt, Alex W., Gharahkhani, Puya, MacGregor, Stuart

“…Serum C-reactive protein (CRP), an important inflammatory marker, has been associated with age-related macular degeneration (AMD) in observational studies;…”
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Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression by Craig, Jamie E., Han, Xikun, Qassim, Ayub, Hassall, Mark, Cooke Bailey, Jessica N., Kinzy, Tyler G., Khawaja, Anthony P., An, Jiyuan, Marshall, Henry, Gharahkhani, Puya, Igo, Robert P., Graham, Stuart L., Healey, Paul R., Ong, Jue-Sheng, Zhou, Tiger, Siggs, Owen, Law, Matthew H., Souzeau, Emmanuelle, Ridge, Bronwyn, Hysi, Pirro G., Burdon, Kathryn P., Mills, Richard A., Landers, John, Ruddle, Jonathan B., Agar, Ashish, Galanopoulos, Anna, White, Andrew J. R., Willoughby, Colin E., Andrew, Nicholas H., Best, Stephen, Vincent, Andrea L., Goldberg, Ivan, Radford-Smith, Graham, Martin, Nicholas G., Montgomery, Grant W., Vitart, Veronique, Hoehn, Rene, Wojciechowski, Robert, Jonas, Jost B., Aung, Tin, Pasquale, Louis R., Cree, Angela Jane, Sivaprasad, Sobha, Vallabh, Neeru A., Viswanathan, Ananth C., Pasutto, Francesca, Haines, Jonathan L., Klaver, Caroline C. W., van Duijn, Cornelia M., Casson, Robert J., Foster, Paul J., Khaw, Peng Tee, Hammond, Christopher J., Mackey, David A., Mitchell, Paul, Lotery, Andrew J., Wiggs, Janey L., Hewitt, Alex W., MacGregor, Stuart

“…Glaucoma, a disease characterized by progressive optic nerve degeneration, can be prevented through timely diagnosis and treatment. We characterize optic nerve…”
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A comprehensive re-assessment of the association between vitamin D and cancer susceptibility using Mendelian randomization by Ong, Jue-Sheng, Dixon-Suen, Suzanne C., Han, Xikun, An, Jiyuan, Liyanage, Upekha, Dusingize, Jean-Cluade, Schumacher, Johannes, Gockel, Ines, Böhmer, Anne, Jankowski, Janusz, Palles, Claire, O’Mara, Tracy, Spurdle, Amanda, Law, Matthew H., Iles, Mark M., Pharoah, Paul, Berchuck, Andrew, Zheng, Wei, Thrift, Aaron P., Olsen, Catherine, Neale, Rachel E., Gharahkhani, Puya, Webb, Penelope M., MacGregor, Stuart

“…Previous Mendelian randomization (MR) studies on 25-hydroxyvitamin D (25(OH)D) and cancer have typically adopted a handful of variants and found no…”
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Vitamin D and overall cancer risk and cancer mortality: a Mendelian randomization study by Ong, Jue-Sheng, Gharahkhani, Puya, An, Jiyuan, Law, Matthew H, Whiteman, David C, Neale, Rachel E, MacGregor, Stuart

“…Abstract There is considerable debate regarding the role that 25-hydroxyvitamin D [25(OH)D] concentrations play in cancer risk or mortality, with earlier…”
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Identifying Shared Risk Genes for Asthma, Hay Fever, and Eczema by Multi-Trait and Multiomic Association Analyses by Guo, Hongping, An, Jiyuan, Yu, Zuguo

“…Asthma, hay fever and eczema are three comorbid diseases with high prevalence and heritability. Their common genetic architectures have not been…”
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miRPlant: an integrated tool for identification of plant miRNA from RNA sequencing data by An, Jiyuan, Lai, John, Sajjanhar, Atul, Lehman, Melanie L, Nelson, Colleen C

“…Small RNA sequencing is commonly used to identify novel miRNAs and to determine their expression levels in plants. There are several miRNA identification tools…”
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Combined analysis of keratinocyte cancers identifies novel genome-wide loci by Liyanage, Upekha E, Law, Matthew H, Han, Xikun, An, Jiyuan, Ong, Jue-Sheng, Gharahkhani, Puya, Gordon, Scott, Neale, Rachel E, Olsen, Catherine M, MacGregor, Stuart, Whiteman, David C

“…The keratinocyte cancers (KC), basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the most common cancers in fair-skinned people. KC treatment…”
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J-Circos: an interactive Circos plotter by An, Jiyuan, Lai, John, Sajjanhar, Atul, Batra, Jyotsna, Wang, Chenwei, Nelson, Colleen C

“…Circos plots are graphical outputs that display three dimensional chromosomal interactions and fusion transcripts. However, the Circos plot tool is not an…”
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Transcriptomic analysis of mRNA expression and alternative splicing during mouse sex determination by Zhao, Liang, Wang, Chenwei, Lehman, Melanie L., He, Mingyu, An, Jiyuan, Svingen, Terje, Spiller, Cassy M., Ng, Ee Ting, Nelson, Colleen C., Koopman, Peter

“…Mammalian sex determination hinges on sexually dimorphic transcriptional programs in developing fetal gonads. A comprehensive view of these programs is crucial…”
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Effect of increased body mass index on risk of diagnosis or death from cancer by Gharahkhani, Puya, Ong, Jue-Sheng, An, Jiyuan, Law, Matthew H., Whiteman, David C., Neale, Rachel E., MacGregor, Stuart

“…Background Whether body mass index (BMI) is causally associated with the risk of being diagnosed with or dying from any cancer remains unclear. Weight…”
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Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases by An, Jiyuan, Gharahkhani, Puya, Law, Matthew H., Ong, Jue-Sheng, Han, Xikun, Olsen, Catherine M., Neale, Rachel E., Lai, John, Vaughan, Tom L., Gockel, Ines, Thieme, René, Böhmer, Anne C., Jankowski, Janusz, Fitzgerald, Rebecca C., Schumacher, Johannes, Palles, Claire, Whiteman, David C., MacGregor, Stuart

“…Gastroesophageal reflux disease (GERD) is caused by gastric acid entering the esophagus. GERD has high prevalence and is the major risk factor for Barrett’s…”
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Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization by Ong, Jue-Sheng, Hwang, Liang-Dar, Zhong, Victor W., An, Jiyuan, Gharahkhani, Puya, Breslin, Paul A. S., Wright, Margaret J., Lawlor, Deborah A., Whitfield, John, MacGregor, Stuart, Martin, Nicholas G., Cornelis, Marilyn C.

“…Consumption of coffee, tea and alcohol might be shaped by individual differences in bitter taste perception but inconsistent observational findings provide…”
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Nerol as a Novel Antifungal Agent: In Vitro Inhibitory Effects on Fusarium oxysporum, Pestalotiopsis neglecta , and Valsa mali and Its Potential Mechanisms against F. oxysporum by Ji, Jingyu, Ma, Weihu, An, Jiyuan, Zhang, Bowen, Sun, Wenzhuo, Zhang, Guocai

“…This study explores the in vitro antifungal effects of nerol, a linear acyclic monoterpene alcohol of plant origin, on , , and . To further investigate the…”
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Symptom-level modelling unravels the shared genetic architecture of anxiety and depression by Thorp, Jackson G., Campos, Adrian I., Grotzinger, Andrew D., Gerring, Zachary F., An, Jiyuan, Ong, Jue-Sheng, Wang, Wei, Shringarpure, Suyash, Byrne, Enda M., MacGregor, Stuart, Martin, Nicholas G., Medland, Sarah E., Middeldorp, Christel M., Derks, Eske M.

“…Depression and anxiety are highly prevalent and comorbid psychiatric traits that cause considerable burden worldwide. Here we use factor analysis and genomic…”
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A Two-Stage Mutual Information Based Bayesian Lasso Algorithm for Multi-Locus Genome-Wide Association Studies by Guo, Hongping, Yu, Zuguo, An, Jiyuan, Han, Guosheng, Ma, Yuanlin, Tang, Runbin

“…Genome-wide association study (GWAS) has turned out to be an essential technology for exploring the genetic mechanism of complex traits. To reduce the…”
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Phenotypic characterization of prostate cancer LNCaP cells cultured within a bioengineered microenvironment by Sieh, Shirly, Taubenberger, Anna V, Rizzi, Simone C, Sadowski, Martin, Lehman, Melanie L, Rockstroh, Anja, An, Jiyuan, Clements, Judith A, Nelson, Colleen C, Hutmacher, Dietmar W

“…Biophysical and biochemical properties of the microenvironment regulate cellular responses such as growth, differentiation, morphogenesis and migration in…”
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Disease-specific, neurosphere-derived cells as models for brain disorders by Matigian, Nicholas, Abrahamsen, Greger, Sutharsan, Ratneswary, Cook, Anthony L, Vitale, Alejandra M, Nouwens, Amanda, Bellette, Bernadette, An, Jiyuan, Anderson, Matthew, Beckhouse, Anthony G, Bennebroek, Maikel, Cecil, Rowena, Chalk, Alistair M, Cochrane, Julie, Fan, Yongjun, Féron, François, McCurdy, Richard, McGrath, John J, Murrell, Wayne, Perry, Chris, Raju, Jyothy, Ravishankar, Sugandha, Silburn, Peter A, Sutherland, Greg T, Mahler, Stephen, Mellick, George D, Wood, Stephen A, Sue, Carolyn M, Wells, Christine A, Mackay-Sim, Alan

“…There is a pressing need for patient-derived cell models of brain diseases that are relevant and robust enough to produce the large quantities of cells…”
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Author Correction: Understanding the role of bitter taste perception in coffee, tea and alcohol consumption through Mendelian randomization by Ong, Jue-Sheng, Hwang, Liang-Dar, Zhong, Victor W., An, Jiyuan, Gharahkhani, Puya, Breslin, Paul A. S., Wright, Margaret J., Lawlor, Deborah A., Whitfield, John, MacGregor, Stuart, Martin, Nicholas G., Cornelis, Marilyn C.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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A microsatellite repeat in PCA3 long non-coding RNA is associated with prostate cancer risk and aggressiveness by Lai, John, Moya, Leire, An, Jiyuan, Hoffman, Andrea, Srinivasan, Srilakshmi, Panchadsaram, Janaththani, Walpole, Carina, Perry-Keene, Joanna L., Chambers, Suzanne, Lehman, Melanie L., Nelson, Colleen C., Clements, Judith A., Batra, Jyotsna

“…Short tandem repeats (STRs) are repetitive sequences of a polymorphic stretch of two to six nucleotides. We hypothesized that STRs are associated with prostate…”
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