Search Results - "An, Jinsu"
-
1
A Fluorescence-Polarization-Based Lipopolysaccharide-Caspase-4 Interaction Assay for the Development of Inhibitors
Published in Molecules (Basel, Switzerland) (11-04-2022)“…Recognition of intracellular lipopolysaccharide (LPS) by Caspase-4 (Casp-4) is critical for host defense against Gram-negative pathogens. LPS binds to the…”
Get full text
Journal Article -
2
Stent-based electrode for radiofrequency ablation in the rat esophagus: a preliminary study
Published in Scientific reports (09-11-2022)“…Endoluminal radiofrequency (RF) ablation has been widely used as a safe and effective treatment for Barrett’s esophagus. However, inadequate RF ablation may…”
Get full text
Journal Article -
3
Dendritic cell activation by an E. coli-derived monophosphoryl lipid A enhances the efficacy of PD-1 blockade
Published in Cancer letters (01-03-2020)“…Cancer immunotherapy is a powerful approach for cancer treatment, but its clinical effects rely on the tumor's immune conditions. In particular, low response…”
Get full text
Journal Article -
4
Caspase-4 disaggregates lipopolysaccharide micelles via LPS-CARD interaction
Published in Scientific reports (29-01-2019)“…Lipopolysaccharides (LPS) are a major component of the outer membrane of Gram-negative bacteria and are pathogen-associated molecular patterns recognized by…”
Get full text
Journal Article -
5
Metabolic engineering of Escherichia coli to produce a monophosphoryl lipid A adjuvant
Published in Metabolic engineering (01-01-2020)“…Monophosphoryl lipid A (MPLA) species, including MPL (a trade name of GlaxoSmithKline) and GLA (a trade name of Immune Design, a subsidiary of Merck), are…”
Get full text
Journal Article -
6
Loss of splicing factor IK impairs normal skeletal muscle development
Published in BMC biology (01-04-2021)“…IK is a splicing factor that promotes spliceosome activation and contributes to pre-mRNA splicing. Although the molecular mechanism of IK has been previously…”
Get full text
Journal Article -
7
Radiofrequency ablation with sine and square electrical waveforms to enhance ablation range
Published in Frontiers in bioengineering and biotechnology (21-08-2024)“…Radiofrequency ablation (RFA) is a local treatment modality for primary liver cancers. Although various input parameters of the RF generator have been adjusted…”
Get full text
Journal Article -
8
Publisher Correction to: Loss of splicing factor IK impairs normal skeletal muscle development
Published in BMC biology (09-06-2021)Get full text
Journal Article -
9
The Lipid A 1-Phosphatase, LpxE, Functionally Connects Multiple Layers of Bacterial Envelope Biogenesis
Published in mBio (18-06-2019)“…Although distinct lipid phosphatases are thought to be required for processing lipid A (component of the outer leaflet of the outer membrane),…”
Get full text
Journal Article -
10
Determining Obstruction in Endotracheal Tubes Using Physical Respiratory Signals
Published in Applied sciences (01-03-2023)“…This study proposes a method for determining obstruction of the endotracheal tube (ET) and its degree and location. Respiratory signals were acquired using a…”
Get full text
Journal Article -
11
Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
Published in Immunity (Cambridge, Mass.) (14-11-2023)“…Gasdermin D (GSDMD)-activated inflammatory cell death (pyroptosis) causes mitochondrial damage, but its underlying mechanism and functional consequences are…”
Get full text
Journal Article -
12
DCE-YOLOv8: Lightweight and Accurate Object Detection for Drone Vision
Published in IEEE access (15-10-2024)“…Object detection using drones is a sophisticated technology that employs a camera mounted on a drone in conjunction with a computer vision algorithm to…”
Get full text
Journal Article -
13
Effects of changes in the waveform and frequency of radio frequency energy on tissue ablation range
Published in PloS one (19-09-2024)“…This study reports the effects of changes in the waveform and frequency of radio frequency (RF) energy on the tissue ablation range. We developed a 70-watt RFA…”
Get full text
Journal Article -
14
Self-Expandable Electrode Based on Chemically Polished Nickel–Titanium Alloy Wire for Treating Endoluminal Tumors Using Bipolar Irreversible Electroporation
Published in ACS applied materials & interfaces (26-07-2023)“…The application of irreversible electroporation (IRE) to endoluminal organs is being investigated; however, the current preclinical evidence and optimized…”
Get full text
Journal Article -
15
Extracellular pyruvate kinase M2 facilitates cell migration by upregulating claudin-1 expression in colon cancer cells
Published in Biochemistry and cell biology (01-03-2020)“…Extensive studies have been reported the non-canonical functions of pyruvate kinase M2 (PKM2) as a kinase, transcriptional regulator, and even cell-to-cell…”
Get more information
Journal Article -
16
Engineering Escherichia coli for constitutive production of monophosphoryl lipid A vaccine adjuvant
Published in Biotechnology and bioengineering (01-03-2024)“…During the COVID‐19 pandemic, expedient vaccine production has been slowed by the shortage of safe and effective raw materials, such as adjuvants, essential…”
Get full text
Journal Article -
17
The lipid A 1‐phosphatase, LpxE, play multiple roles in bacteria envelope biogenesis
Published in The FASEB journal (01-04-2018)“…Gram‐negative bacteria cell envelope is multilayered structure that consist of lipopolysaccharide at outer leaflet of the outer‐membrane, peptidoglycan at…”
Get full text
Journal Article -
18
The Multifaceted Role of Lipid A 1‐phosphatase in Bacterial Envelope Biogenesis
Published in The FASEB journal (01-04-2019)“…Gram‐negative bacterial cell envelope consists of a phospholipid bilayer inner membrane, a peptidoglycan layer and an asymmetric bilayer outer membrane with…”
Get full text
Journal Article -
19
Split-tracrRNA as an efficient tracrRNA system with an improved potential of scalability
Published in Biomaterials science (02-05-2023)“…Due to the relatively long sequence, tracrRNAs are chemically less synthesizable than crRNAs, leading to limited scalability of RNA guides for CRISPR-Cas9…”
Get more information
Journal Article -
20
The crystal structure of a natural DNA polymerase complexed with mirror DNA
Published in Chemical communications (Cambridge, England) (18-02-2020)“…The intrinsic l-DNA binding properties of a natural DNA polymerase was discovered. The binding affinity of Dpo4 polymerase for l-DNA was comparable to that for…”
Get more information
Journal Article