Search Results - "An, Hyun‐Jung"

Stat2 stability regulation: an intersection between immunity and carcinogenesis by Lee, Cheol-Jung, An, Hyun-Jung, Cho, Eun Suh, Kang, Han Chang, Lee, Joo Young, Lee, Hye Suk, Cho, Yong-Yeon

“…Signal transducer and activator of transcription (STAT2) is a member of the STAT family that plays an essential role in immune responses to extracellular and…”
Get full text

Regulation of hypoxia responses by flavin adenine dinucleotide‐dependent modulation of HIF‐1α protein stability by Yang, Suk‐Jin, Park, Young Soo, Cho, Jung Hee, Moon, Byul, An, Hyun‐Jung, Lee, Ju Yeon, Xie, Zhi, Wang, Yuli, Pocalyko, David, Lee, Dong Chul, Sohn, Hyun Ahm, Kang, Minho, Kim, Jin Young, Kim, Eunhee, Park, Kyung Chan, Kim, Jung‐Ae, Yeom, Young Il

“…Oxygen deprivation induces a range of cellular adaptive responses that enable to drive cancer progression. Here, we report that lysine‐specific demethylase 1…”
Get full text

FBXW7-mediated ERK3 degradation regulates the proliferation of lung cancer cells by An, Hyun-Jung, Lee, Cheol-Jung, Lee, Ga-Eun, Choi, Youngwon, Jeung, Dohyun, Chen, Weidong, Lee, Hye Suk, Kang, Han Chang, Lee, Joo Young, Kim, Dae Joon, Choi, Jin-Sung, Cho, Eun Suh, Choi, Jong-Soon, Cho, Yong-Yeon

“…Extracellular signal-regulated kinase 3 (ERK3) is an atypical member of the mitogen-activated protein kinase (MAPK) family, members of which play essential…”
Get full text

Higd-1a interacts with Opa1 and is required for the morphological and functional integrity of mitochondria by An, Hyun-Jung, Cho, Geunyoung, Lee, Jie-Oh, Paik, Sang-Gi, Kim, Young Sang, Lee, Hayyoung

“…The activity and morphology of mitochondria are maintained by dynamic fusion and fission processes regulated by a group of proteins residing in, or attached…”
Get full text

RSK2-Mediated ELK3 Activation Enhances Cell Transformation and Breast Cancer Cell Growth by Regulation of c-fos Promoter Activity by Yoo, Sun-Mi, Lee, Cheol-Jung, An, Hyun-Jung, Lee, Joo Young, Lee, Hye Suk, Kang, Han Chang, Cho, Sung-Jun, Kim, Seung-Min, Park, Juhee, Kim, Dae Joon, Cho, Yong-Yeon

“…Ribosomal S6 kinase 2 (RSK2), regulated by Ras/Raf/MEKs/ERKs, transmits upstream activation signals to downstream substrates including kinases and…”
Get full text

Fargesin Inhibits EGF-Induced Cell Transformation and Colon Cancer Cell Growth by Suppression of CDK2/Cyclin E Signaling Pathway by Lee, Ga-Eun, Lee, Cheol-Jung, An, Hyun-Jung, Kang, Han Chang, Lee, Hye Suk, Lee, Joo Young, Oh, Sei-Ryang, Cho, Sung-Jun, Kim, Dae Joon, Cho, Yong-Yeon

“…Although the lignan compound fargesin is a major ingredient in Shin-Yi, the roles of fargesin in carcinogenesis and cancer cell growth have not been…”
Get full text

Magnolin targeting of ERK1/2 inhibits cell proliferation and colony growth by induction of cellular senescence in ovarian cancer cells by Song, Ji‐Hong, Lee, Cheol‐Jung, An, Hyun‐Jung, Yoo, Sun‐Mi, Kang, Han C., Lee, Joo Y., Kim, Kwang D., Kim, Dae J., Lee, Hye S., Cho, Yong‐Yeon

“…Ras/Raf/MEKs/ERKs and PI3 K/Akt/mTOR signaling pathways have key roles in cancer development and growth processes, as well as in cancer malignance and…”
Get full text

Dysregulated CREB3 cleavage at the nuclear membrane induces karyoptosis-mediated cell death by Lee, Ga-Eun, Bang, Geul, Byun, Jiin, Lee, Cheol-Jung, Chen, Weidong, Jeung, Dohyun, An, Hyun-Jung, Kang, Han Chang, Lee, Joo Young, Lee, Hye Suk, Hong, Young-Soo, Kim, Dae Joon, Keniry, Megan, Kim, Jin Young, Choi, Jin-Sung, Fanto, Manolis, Cho, Sung-Jun, Kim, Kwang-Dong, Cho, Yong-Yeon

“…Cancer cells often exhibit resistance to apoptotic cell death, but they may be vulnerable to other types of cell death. Elucidating additional mechanisms that…”
Get full text

Epimagnolin targeting on an active pocket of mammalian target of rapamycin suppressed cell transformation and colony growth of lung cancer cells by Yoo, Sun‐Mi, Lee, Cheol‐Jung, Kang, Han Chang, Lee, Hye Suk, Lee, Joo Young, Kim, Kwang Dong, Kim, Dae Joon, An, Hyun‐Jung, Cho, Yong‐Yeon

“…Mammalian target of rapamycin (mTOR) has a pivotal role in carcinogenesis and cancer cell proliferation in diverse human cancers. In this study, we observed…”
Get full text

MEKs/ERKs-mediated FBXO1/E2Fs interaction interference modulates G1/S cell cycle transition and cancer cell proliferation by Lee, Ga-Eun, Jeung, Dohyun, Chen, Weidong, Byun, Jiin, Lee, Joo Young, Kang, Han Chang, Lee, Hye Suk, Kim, Dae Joon, Choi, Jin-Sung, Lee, Cheol-Jung, An, Hyun-Jung, Cho, Yong-Yeon

“…E2F 1, 2, and 3a, (refer to as E2Fs) are a subfamily of E2F transcription factor family that play essential roles in cell-cycle progression, DNA replication,…”
Get full text

Crystallographic and Mutational Analysis of the CD40-CD154 Complex and Its Implications for Receptor Activation by An, Hyun-Jung, Kim, Young Jin, Song, Dong Hyun, Park, Beom Suk, Kim, Ho Min, Lee, Ju Dong, Paik, Sang-Gi, Lee, Jie-Oh, Lee, Hayyoung

“…CD40 is a tumor necrosis factor receptor (TNFR) family protein that plays an important role in B cell development. CD154/CD40L is the physiological ligand of…”
Get full text

Coris picta, a new record of the Comb wrasse (Perciformes: Labridae) from Korea by An, Jung-Hyun, Kim, Byung-Jik, Kim, Sang-Kil, Lee, Seung-Hyun

“…Based on a single specimen (100.3 mm SL) collected from the southern coastal waters of Jejudo Island, Coris picta is described as the first record from Korea…”
Get full text

First reliable record of the Bluestriped fangblenny, Plagiotremus rhinorhynchos (Perciformes: Blenniidae) in Korea by An, Jung-Hyun, Kim, Byung-Jik, Bae, Yang-Seop

“…Here, we present the first reliable record of the Bluestriped fangblenny, Plagiotremus rhinorhynchos in Korea, based on two specimens (65.9–67.1 mm in standard…”
Get full text

First reliable record of a blenny, Petroscirtes springeri (Perciformes: Blenniidae) from the southern coastal waters of Jeju island, Korea by An, Jung-Hyun, Kim, Byung-Jik, Bae, Yang-Seop

“…Three species (Petroscrites breviceps, P. springeri and P. variabilis) belong to the blenny genus Petroscirtes have been recognized from the Korean waters to…”
Get full text

Surface modification using bio-inspired adhesive polymers based on polyaspartamide derivatives by An, Jung Hyun, Huynh, Ngoc Thach, Sil Jeon, Young, Kim, Ji-Heung

“…The catechol functional group of dopamine (3,4‐dihydroxyphenethylamine) has the ability to form strong adhesive bonds to inorganic and organic surfaces in…”
Get full text

Activation of Ras Up-regulates Pro-apoptotic BNIP3 in Nitric Oxide-induced Cell Death by An, Hyun-Jung, Maeng, Oky, Kang, Kyoung-Hee, Lee, Jie-Oh, Kim, Young-Sang, Paik, Sang-Gi, Lee, Hayyoung

“…Nitric oxide (NO) produced by NO synthases causes nitration and nitrosylation of cellular factors. We have shown previously that endogenously produced or…”
Get full text

A CNN-based automatic vulnerability detection by An, Jung Hyun, Wang, Zhan, Joe, Inwhee

“…With the advent of the Internet, the activities of individuals and businesses have expanded into the online realm. As a result, vulnerabilities that result in…”
Get full text

Silencing of BNIP3 Results from Promoter Methylation by DNA Methyltransferase 1 Induced by the Mitogen-Activated Protein Kinase Pathway by An, H.J., Chungnam National University, Daejeon, Republic of Korea, Lee, H.Y., Chungnam National University, Daejeon, Republic of Korea, Paik, S.G., Chungnam National University, Daejeon, Republic of Korea

“…We have previously shown that Ras mediates NO-induced BNIP3 expression via the MEK-ERK-HIF-1 pathway i n mouse macrophages, and that NO-induced death results…”
Get full text

FBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formation by Lee, Cheol-Jung, An, Hyun-Jung, Kim, Seung-Min, Yoo, Sun-Mi, Park, Juhee, Lee, Ga-Eun, Kim, Woo-Young, Kim, Dae Joon, Kang, Han Chang, Lee, Joo Young, Lee, Hye Suk, Cho, Sung-Jun, Cho, Yong-Yeon

“…In this study, we provide critical evidence that STAT2 stability regulation plays an essential role in melanoma cell proliferation and colony growth. We found…”
Get full text

The Crystal Structure of Lipopolysaccharide Binding Protein Reveals the Location of a Frequent Mutation that Impairs Innate Immunity by Eckert, Jana K., Kim, Young J., Kim, Jung I., Gürtler, Kathleen, Oh, Djin-Ye, Sur, Saubashya, Lundvall, Linn, Hamann, Lutz, van der Ploeg, Anke, Pickkers, Peter, Giamarellos-Bourboulis, Evangelos, Kubarenko, Andriy V., Weber, Alexander N., Kabesch, Michael, Kumpf, Oliver, An, Hyun-Jung, Lee, Jie-Oh, Schumann, Ralf R.

“…Lipopolysaccharide (LPS) binding protein (LBP) is an acute-phase protein that initiates an immune response after recognition of bacterial LPS. Here, we report…”
Get full text