Search Results - "An, Chengrui"

Emerging roles of Nrf2 and phase II antioxidant enzymes in neuroprotection by Zhang, Meijuan, An, Chengrui, Gao, Yanqin, Leak, Rehana K, Chen, Jun, Zhang, Feng

“…Phase II metabolic enzymes are a battery of critical proteins that detoxify xenobiotics by increasing their hydrophilicity and enhancing their disposal. These…”
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Demyelination as a rational therapeutic target for ischemic or traumatic brain injury by Shi, Hong, Hu, Xiaoming, Leak, Rehana K., Shi, Yejie, An, Chengrui, Suenaga, Jun, Chen, Jun, Gao, Yanqin

“…Previous research on stroke and traumatic brain injury (TBI) heavily emphasized pathological alterations in neuronal cells within gray matter. However, recent…”
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Molecular dialogs between the ischemic brain and the peripheral immune system: dualistic roles in injury and repair by An, Chengrui, Shi, Yejie, Li, Peiying, Hu, Xiaoming, Gan, Yu, Stetler, Ruth A, Leak, Rehana K, Gao, Yanqin, Sun, Bao-Liang, Zheng, Ping, Chen, Jun

“…Immune and inflammatory responses actively modulate the pathophysiological processes of acute brain injuries such as stroke. Soon after the onset of stroke,…”
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Neurobiology of microglial action in CNS injuries: receptor-mediated signaling mechanisms and functional roles by Hu, Xiaoming, Liou, Anthony K F, Leak, Rehana K, Xu, Mingyue, An, Chengrui, Suenaga, Jun, Shi, Yejie, Gao, Yanqin, Zheng, Ping, Chen, Jun

“…Microglia are the first line of immune defense against central nervous system (CNS) injuries and disorders. These highly plastic cells play dualistic roles in…”
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A high-resolution route map reveals distinct stages of chondrocyte dedifferentiation for cartilage regeneration by Chen, Yishan, Yu, Yeke, Wen, Ya, Chen, Juan, Lin, Junxin, Sheng, Zixuan, Zhou, Wenyan, Sun, Heng, An, Chengrui, Chen, Jiansong, Wu, Weiliang, Teng, Chong, Wei, Wei, Ouyang, Hongwei

“…Articular cartilage damage is a universal health problem. Despite recent progress, chondrocyte dedifferentiation has severely compromised the clinical outcomes…”
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The blood brain barrier in cerebral ischemic injury – Disruption and repair by Zhang, Wenting, Zhu, Ling, An, Chengrui, Wang, Rongrong, Yang, Liqun, Yu, Weifeng, Li, Peiying, Gao, Yanqin

“…With the emergence of novel technologies and ground breaking concepts in BBB basic research in the past decades, the researchers’ attention on the critical…”
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Thymic epithelial cell fate and potency in early organogenesis assessed by single cell transcriptional and functional analysis by Farley, Alison Mary, Chengrui, An, Palmer, Sam, Liu, Dong, Kousa, Anastasia I, Rouse, Paul, Major, Viktoria, Sweetman, Joanna, Morys, Jan, Corsinotti, Andrea, Nichols, Jennifer, Ure, Janice, McLay, Renee, Boulter, Luke, Chapman, S Jon, Tomlinson, Simon R, Blackburn, C Clare

“…During development, cortical (c) and medullary (m) thymic epithelial cells (TEC) arise from the third pharyngeal pouch endoderm. Current models suggest that…”
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Correction: A high-resolution route map reveals distinct stages of chondrocyte dedifferentiation for cartilage regeneration by Chen, Yishan, Yu, Yeke, Wen, Ya, Chen, Juan, Lin, Junxin, Sheng, Zixuan, Zhou, Wenyan, Sun, Heng, An, Chengrui, Chen, Jiansong, Wu, Weiliang, Teng, Chong, Wei, Wei, Ouyang, Hongwei

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Reconstructing Lineage Hierarchies of Mouse Uterus Epithelial Development Using Single-Cell Analysis by Wu, Bingbing, An, Chengrui, Li, Yu, Yin, Zi, Gong, Lin, Li, Zhenli, Liu, Yixiao, Heng, Boon Chin, Zhang, Dandan, Ouyang, Hongwei, Zou, Xiaohui

“…The endometrial layer comprises luminal and glandular epithelia that both develop from the same simple layer of fetal uterine epithelium. Mechanisms of uterine…”
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SFRP4+ stromal cell subpopulation with IGF1 signaling in human endometrial regeneration by Wu, Bingbing, Li, Yu, Nie, Nanfang, Shen, Xilin, Jiang, Wei, Liu, Yanshan, Gong, Lin, An, Chengrui, Zhao, Kun, Yao, Xudong, Yuan, Chunhui, Hu, Jinghui, Zhao, Wei, Qian, Jianhua, Zou, XiaoHui

“…Our understanding of full-thickness endometrial regeneration after injury is limited by an incomplete molecular characterization of the cell populations…”
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Gefitinib for Epidermal Growth Factor Receptor Activated Osteoarthritis Subpopulation Treatment by Sun, Heng, Wu, Yan, Pan, Zongyou, Yu, Dongsheng, Chen, Pengfei, Zhang, Xiaoan, Wu, Haoyu, Zhang, Xiaolei, An, Chengrui, Chen, Yishan, Qin, Tian, Lei, Xiaoyue, Yuan, Chunhui, Zhang, Shufang, Zou, Weiguo, Ouyang, Hongwei

“…Osteoarthritis (OA) is a leading cause of physical disability among aging populations, with no available drugs able to efficiently restore the balance between…”
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High-Resolution Dissection of Chemical Reprogramming from Mouse Embryonic Fibroblasts into Fibrocartilaginous Cells by Chen, Yishan, Wu, Bingbing, Lin, Junxin, Yu, Dongsheng, Du, Xiaotian, Sheng, Zixuan, Yu, Yeke, An, Chengrui, Zhang, Xiaoan, Li, Qikai, Zhu, Shouan, Sun, Heng, Zhang, Xianzhu, Zhang, Shufang, Zhou, Jing, Bunpetch, Varitsara, El-Hashash, Ahmed, Ji, Junfeng, Ouyang, Hongwei

“…Articular cartilage injury and degeneration causing pain and loss of quality-of-life has become a serious problem for increasingly aged populations. Given the…”
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Targeting downstream subcellular YAP activity as a function of matrix stiffness with Verteporfin-encapsulated chitosan microsphere attenuates osteoarthritis by Zhang, Xianzhu, Cai, Dandan, Zhou, Feifei, Yu, Jie, Wu, Xinyu, Yu, Dongsheng, Zou, Yiwei, Hong, Yi, Yuan, Chunhui, Chen, Yishan, Pan, Zongyou, Bunpetch, Varitsara, Sun, Heng, An, Chengrui, Yi-Chin, Toh, Ouyang, Hongwei, Zhang, Shufang

“…Changes in the stiffness of chondrocyte extracellular matrix (ECM) are involved in the pathological progression of osteoarthritis (OA). However, the downstream…”
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Single-cell RNA-seq reveals functionally distinct biomaterial degradation-related macrophage populations by Huang, Jiayun, Fan, Chunmei, Chen, Yangwu, Ye, Jinchun, Yang, Yuwei, Tang, Chenqi, Zhang, Hong, Fei, Yang, An, Chengrui, Xie, Yuanhao, Liu, Hua, Yin, Zi, Chen, Weishan, Heng, Boon Chin, Ouyang, Hongwei, Chen, Xiao, Shen, Weiliang

“…Macrophages play crucial roles in host tissue reaction to biomaterials upon implantation in vivo. However, the complexity of biomaterial degradation-related…”
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Structural, functional and molecular pathogenesis of pelvic organ prolapse in patient and Loxl1 deficient mice by Li, Yu, Nie, Nanfang, Gong, Lin, Bao, Fangyuan, An, Chengrui, Cai, Hongxia, Yao, Xudong, Liu, Yanshan, Yang, Chunbo, Wu, Bingbing, Zou, XiaoHui

“…Pelvic organ prolapse is a worldwide health problem to elderly women. Understanding its pathogenesis and an ideal animal model are crucial to developing…”
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Scriptaid, a Novel Histone Deacetylase Inhibitor, Protects Against Traumatic Brain Injury via Modulation of PTEN and AKT Pathway by Wang, Guohua, Jiang, Xiaoyan, Pu, Hongjian, Zhang, Wenting, An, Chengrui, Hu, Xiaoming, Liou, Anthony Kian-Fong, Leak, Rehana K., Gao, Yanqin, Chen, Jun

“…Issue Title: Multiple Sclerosis Therapeutics Traumatic brain injury (TBI) is a leading cause of motor and cognitive deficits in young adults for which there is…”
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Nano genome altas (NGA) of body wide organ responses by Wu, Bingbing, Li, Yu, Nie, Nanfang, Xu, Jiaqi, An, Chengrui, Liu, Yixiao, Wang, Yafei, Chen, Yishan, Gong, Lin, Li, Qikai, Giusto, Elena, Bunpetch, Varitsara, Zhang, Dandan, Ouyang, HongWei, Zou, XiaoHui

“…Nanoparticles are widely developed and utilized in the pharmaceutical and medicine industry, as they can be easily distributed and infiltrated throughout the…”
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Severity-Dependent Long-Term Spatial Learning-Memory Impairment in a Mouse Model of Traumatic Brain Injury by An, Chengrui, Jiang, Xiaoyan, Pu, Hongjian, Hong, Dandan, Zhang, Wenting, Hu, Xiaoming, Gao, Yanqin

“…Traumatic brain injury (TBI) is a major cause of death and disability in young adults. Long-term mental disability often occurs in patients suffering moderate…”
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Scriptaid, a Novel Histone Deacetylase Inhibitor, Protects Against Traumatic Brain Injury via Modulation of PTEN and AKT Pathway: Scriptaid Protects Against TBI via AKT by Wang, Guohua, Jiang, Xiaoyan, Pu, Hongjian, Zhang, Wenting, An, Chengrui, Hu, Xiaoming, Liou, Anthony Kian-Fong, Leak, Rehana K., Gao, Yanqin, Chen, Jun

“…Traumatic brain injury (TBI) is a leading cause of motor and cognitive deficits in young adults for which there is no effective therapy. The present study…”
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Soft Artificial Bladder Detrusor by Yang, Xuxu, An, Chengrui, Liu, Shuting, Cheng, Tingyu, Bunpetch, Varitsara, Liu, Yixiao, Dong, Shurong, Li, Shijian, Zou, Xiaohui, Li, Tiefeng, Ouyang, Hongwei, Wu, Zhaohui, Yang, Wei

“…Developing soft devices for invasive procedures bears great importance for human health. The softness and large strain actuation of responsive hydrogels…”
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