Search Results - "Amtul, Zareen"

Role of Delayed Neuroglial Activation in Impaired Cerebral Blood Flow Restoration Following Comorbid Injury by Amtul, Zareen, Randhawa, Jasmine, Najdat, Abdullah N., Hill, David J., Arany, Edith J.

“…Besides other causes, ischemia and Alzheimer’s disease pathology is also linked to decreased cerebral blood flow (CBF). There is little or no consensus about…”
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Pathological Changes in Microvascular Morphology, Density, Size and Responses Following Comorbid Cerebral Injury by Amtul, Zareen, Yang, Jun, Lee, Ting-Yim, Cechetto, David F

“…Aberrations in brain microcirculation and the associated increase in blood-brain-barrier (BBB) permeability in addition to neuroinflammation and Aβ deposition…”
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Correction to: Role of Delayed Neuroglial Activation in Impaired Cerebral Blood Flow Restoration Following Comorbid Injury by Amtul, Zareen, Randhawa, Jasmine, Najdat, Abdullah N., Hill, David J., Arany, Edith J.

“…The original version of this article contained a random order of part labels for Fig. 4. The correct caption of Fig. 4 with correct order of part labels is…”
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Engineering of fluorescent or photoactive Trojan probes for detection and eradication of β-Amyloids by Aziz, Amal A., Siddiqui, Rafat A., Amtul, Zareen

“…Trojan horse technology institutes a potentially promising strategy to bring together a diagnostic or cell-based drug design and a delivery platform. It…”
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Correction: DHA Supplemented in Peptamen Diet Offers No Advantage in Pathways to Amyloidosis: Is It Time to Evaluate Composite Lipid Diet? by Amtul, Zareen, Keet, Mary, Wang, Lin, Merrifield, Peter, Westaway, David, Rozmahel, Richard F

“…[This corrects the article DOI: 10.1371/journal.pone.0024094.]…”
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Hemodynamic effects of combined focal cerebral ischemia and amyloid protein toxicity in a rat model: a functional CT study by Yang, Jun, d'Esterre, Christopher D, Amtul, Zareen, Cechetto, David F, Lee, Ting Yim

“…Clinical evidence indicates that cerebral ischemia (CI) and a pathological factor of Alzheimer's disease, the β-amyloid (Aβ) protein, can increase the rate of…”
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DHA supplemented in peptamen diet offers no advantage in pathways to amyloidosis: is it time to evaluate composite lipid diet? by Amtul, Zareen, Keet, Mary, Wang, Lin, Merrifield, Peter, Westaway, David, Rozmahel, Richard F

“…Numerous reports have documented the beneficial effects of dietary docosahexaenoic acid (DHA) on beta-amyloid production and Alzheimer's disease (AD). However,…”
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Kinetics of novel competitive inhibitors of urease enzymes by a focused library of oxadiazoles/thiadiazoles and triazoles by Amtul, Zareen, Rasheed, Maimoona, Choudhary, Mohammad Iqbal, Rosanna, Supino, Khan, Khalid M., Atta-ur-Rahman

“…Based on structure of the substrate of urease and for the purpose of designing pharmacophore models for urease inhibitors, which could be effective in…”
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Characteristics and Outcome of Obstetric Acute Kidney Injury in Pakistan: A Single-center Prospective Observational Study by Bokhari, Syed Rizwan A, Inayat, Faisal, Jabeen, Mah, Sardar, Zumar, Saeed, Sara, Malik, Ayesha M, Nasir, Sabin, Zareen, Amtul, Ahmad, Hafiz Ijaz

“…Introduction Acute kidney injury (AKI) continues to be a cause of increased morbidity and mortality in pregnant women. While studies have been conducted on the…”
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Why therapies for Alzheimer’s disease do not work: Do we have consensus over the path to follow? by Amtul, Zareen

“…Highlights • Phase of disappointment & reservation about future path in Alzheimer’s research. • Reviewed some alarming concerns related to the primary issues…”
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Dietary lipids and Alzheimer's disease by Amtul, Zareen, Park, Jae Wook, Murphy, M Paul, Siddiqui, Rafat A, Choudhary, Muhammad Iqbal

“…There is a clear need of dietary recommendations or guidelines at both population and/or individual levels, to prevent the Alzheimer's disease or reduce its…”
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A Presenilin 1 Mutation Associated with Familial Frontotemporal Dementia Inhibits γ-Secretase Cleavage of APP and Notch by Amtul, Zareen, Lewis, Patrick A., Piper, Sian, Crook, Richard, Baker, Matt, Findlay, Kirk, Singleton, Andrew, Hogg, Marion, Younkin, Linda, Younkin, Steven G., Hardy, John, Hutton, Michael, Boeve, Bradley F., Tang-Wai, David, Golde, Todd E.

“…A novel presenilin 1 mutation, insR352, associated with a frontal temporal dementia phenotype has been identified (E. A. Rogaeva et al., 2001, Neurology 57,…”
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Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo by Brijbassi, Sonya, Amtul, Zareen, Newbigging, Susan, Westaway, David, St George-Hyslop, Peter, Rozmahel, Richard F

“…Abstract Nicastrin is an integral member of PS-complexes that perform γ-secretase cleavage of numerous type I membrane proteins including amyloid precursor…”
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Neural plasticity and memory: molecular mechanism by Amtul, Zareen, Atta-Ur-Rahman

“…Deciphering the cellular and molecular mechanisms of memory has been an important topic encompassing the learning and memory domain besides the…”
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Canadian Muslim Excellence: A Time to Celebrate, Educate, and Reflect: Canadian Muslims by AMTUL, ZAREEN, King, April, Lia, Adita

“…This study redresses the limited presence of stories of Muslims in Canadian archival history and curriculum, drawing attention to the racial issues as an…”
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Canadian Muslim Excellence: A Time to Celebrate, Educate, and Reflect by ZAREEN AMTUL, April King, Adita Lia

“…This study redresses the limited presence of stories of Muslims in Canadian archival history and curriculum, drawing attention to the racial issues as an…”
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A modular inquiry-based semester theme that integrates data science education and bioinformatics in protein structure function courses by Amtul, Zareen, Firoozbakht, Forough, Rezaeian, Iman, Aziz, Arham A, Gehlaut, Padmini

“…Abstract Background With an exponential growth in biological data and computing power, familiarity with bioinformatics has become a demanding and popular skill…”
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Developing Trojan horses to induce, diagnose and suppress Alzheimer’s pathology by Aziz, Amal A., Amtul, Zareen

“…Monoclonal antibodies for receptors on blood-brain barrier can act as molecular Trojan horses to transport the fused novel classes of re-engineered AD…”
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Detrimental effects of arachidonic acid and its metabolites in cellular and mouse models of Alzheimer's disease: structural insight by Amtul, Zareen, Uhrig, Markus, Wang, Lin, Rozmahel, Richard F, Beyreuther, Konrad

“…Abstract Inflammation is believed to be integral to the pathogenesis of Alzheimer's disease (AD). Arachidonic acid (AA) is the most important omega-6 fatty…”
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Building Industry-Inspired Medical Biotechnology Investigative Laboratories to Enhance Experiential Capstone Courses by Amtul, Zareen, Seifi, Moutasem, Asif, Erfan S., Ata, Athar

“…According to national labor market information study, access to talent is the greatest business challenge Canadian biotech companies are facing. We, therefore,…”
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