Search Results - "Amrutkar, Suyog"

Imine/amide–imidazole conjugates derived from 5-amino-4-cyano-N1-substituted benzyl imidazole: Microwave-assisted synthesis and anticancer activity via selective topoisomerase-II-α inhibition by Negi, Arvind, Alex, Jimi Marin, Amrutkar, Suyog M., Baviskar, Ashish T., Joshi, Gaurav, Singh, Sandeep, Banerjee, Uttam C., Kumar, Raj

“…[Display omitted] Microwave-accelerated synthesis and anticancer activity of novel imine/amide–imidazole conjugates derived from 5-amino-4-cyano-N1-substituted…”
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Switch in Site of Inhibition: A Strategy for Structure-Based Discovery of Human Topoisomerase IIα Catalytic Inhibitors by Baviskar, Ashish T, Amrutkar, Suyog M, Trivedi, Neha, Chaudhary, Vikas, Nayak, Anmada, Guchhait, Sankar K, Banerjee, Uttam C, Bharatam, Prasad V, Kundu, Chanakya N

“…A study of structure-based modulation of known ligands of hTopoIIα, an important enzyme involved in DNA processes, coupled with synthesis and in vitro assays…”
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One-pot synthesis of (R)-1-(1-naphthyl)ethanol by stereoinversion using Candida parapsilosis by Amrutkar, Suyog Madhav, Banoth, Linga, Banerjee, Uttam Chand

“…(R)-1-(1-Naphthyl)ethanol is an essential chiral substrate for the synthesis of nonactin and dihydro-[1H]-quinoline-2-one derivatives. Stereoinversion of…”
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Scaffold-Hopping of Aurones: 2‑Arylideneimidazo[1,2‑a]pyridinones as Topoisomerase IIα-Inhibiting Anticancer Agents by Priyadarshani, Garima, Nayak, Anmada, Amrutkar, Suyog M, Das, Sarita, Guchhait, Sankar K, Kundu, Chanakya N, Banerjee, Uttam C

“…Scaffold-hopping of bioactive natural product aurones has been studied for the first time. 2-Arylideneimidazo­[1,2-a]­pyridinones as potential topoisomerase…”
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Anticancer activity of dihydropyrazolo[1,5‐c]quinazolines against rat C6 glioma cells via inhibition of topoisomerase II by Kaur, Gagandeep, Cholia, Ravi P., Joshi, Gaurav, Amrutkar, Suyog M., Kalra, Sourav, Mantha, Anil K., Banerjee, Uttam C., Kumar, Raj

“…The design and synthesis of dihydropyrazolo[1,5‐c]quinazolines (1a–h) as human topoisomerase II (TopoII) catalytic inhibitors are reported. The compounds were…”
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Sulfinate Based Selective Labeling of 5‑Hydroxymethylcytosine: Application to Biotin Pull Down Assay by Wu, Qiong, Amrutkar, Suyog Madhav, Shao, Fangwei

“…We developed an enzyme-free, chemical method to selectively label the epigenetic base, 5-hydroxymethylcytosine (hmC) with versatile sulfinate reagents in…”
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Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of topoisomerase IIα by Priyadarshani, Garima, Amrutkar, Suyog, Nayak, Anmada, Banerjee, Uttam C., Kundu, Chanakya N., Guchhait, Sankar K.

“…A strategy of scaffold-hopping of bioactive natural products, flavones and isoflavones, leading to target-based discovery of potent anticancer agents has been…”
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E-pharmacophore guided discovery of pyrazolo[1,5-c]quinazolines as dual inhibitors of topoisomerase-I and histone deacetylase by Joshi, Gaurav, Kalra, Sourav, Yadav, Umesh Prasad, Sharma, Praveen, Singh, Pankaj Kumar, Amrutkar, Suyog, Ansari, Arshad J., Kumar, Santosh, Sharon, Ashoke, Sharma, Sadhana, Sawant, Devesh M., Banerjee, Uttam C., Singh, Sandeep, Kumar, Raj

“…[Display omitted] •Non-camptothecin analogues among 11 motifs of pyrazoloquinazolines are reported.•E-pharmacophore drug design guided discovery of…”
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Imine/amide–imidazole conjugates derived from 5-amino-4-cyano- N 1-substituted benzyl imidazole: Microwave-assisted synthesis and anticancer activity via selective topoisomerase-II-α inhibition by Negi, Arvind, Alex, Jimi Marin, Amrutkar, Suyog M., Baviskar, Ashish T., Joshi, Gaurav, Singh, Sandeep, Banerjee, Uttam C., Kumar, Raj

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