Search Results - "Amr, Khalda Sayed"
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Genetic and Molecular Evaluation: Reporting Three Novel Mutations and Creating Awareness of Pycnodysostosis Disease
Published in Genes (29-09-2021)“…Pycnodysostosis is a rare autosomal recessive disorder with characteristic diagnostic manifestations. This study aims to phenotype and provide molecular…”
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Is There a Link between Human Herpesvirus Infection and Toll-like Receptors in the Pathogenesis of Pityriasis Rosea? A Case-control Study
Published in Acta dermatovenerologica Croatica (01-12-2016)“…Human herpesvirus (HHV) 6 and 7 are involved in the pathogenesis of pityriasis rosea (PR). Our aim was to evaluate the role of the innate immune response in PR…”
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Study the association of microRNA polymorphisms (miR‐146a, miR‐4513) with the risk of coronary heart diseases in Egyptian population
Published in Journal of biochemical and molecular toxicology (01-03-2023)“…Coronary heart disease (CHD) is the most prevalent cause of cardiovascular mortality in the world. It is well established that microRNAs (miRNAs) and their…”
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Measuring the differential expression of the major hypermethylated tumor suppressor genes in tissues of primary hepatocellular carcinoma
Published in Journal of Genetic Engineering and Biotechnology (01-09-2024)“…Hepatocarcinogenesis is a multifactorial process that arises from a integration of genetic and epigenetic anomalies leading to abnormal gene expression and…”
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Primary hyperoxaluria type 1 in children: Clinical classification, renal replacement therapy, and outcome in a single centre experience
Published in Therapeutic apheresis and dialysis (01-02-2022)“…Primary hyperoxaluria type 1 (PH1) is a rare disease that is challenged by the overproduced oxalate and commonly presented with radiopaque renal stones or…”
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Craniofacial anthropometric measurements of the cohort of Egyptian male school children and their utility in detection of abnormalities
Published in Bulletin of the National Research Centre (01-12-2024)“…Background Anthropology is a scientific discipline which applies scientific methods to identify and quantitate inter-individual variations in body structure…”
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Insights for hepatitis C virus related hepatocellular carcinoma genetic biomarkers: Early diagnosis and therapeutic intervention
Published in World journal of hepatology (28-10-2016)“…The current review explores the role of emerging molecular contributing factors in liver carcinogenesis on top of hepatitis C virus(HCV). Here we will try to…”
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A study of the association of glutathione S-transferase M1/T1 polymorphisms with susceptibility to vitiligo in Egyptian patients
Published in Anais brasileiros de dermatología (01-01-2018)“…The association of glutathione S-transferases M1/T1 (GSTM1/T1) null polymorphisms with vitiligo was proposed in several studies including two Egyptian studies…”
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APOA2 Polymorphism in Relation to Obesity and Lipid Metabolism
Published in Cholesterol (01-01-2013)“…Objectives. This study aims to analysis the relationship between c.-492T>C polymorphism in APOA2 gene and the risk for obesity in a sample of Egyptian…”
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The effect of insulin‐loaded gold and carboxymethyl chitosan nanoparticles on gene expression of glucokinase and pyruvate kinase in rats with diabetes type 1
Published in Journal of food biochemistry (01-12-2022)“…The goal of this study was to see how effective subcutaneous (SC) insulin is and two different types of oral insulin‐loaded nanoparticles (INS) including…”
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Association of a novel Granulocyte‐Macrophage Colony‐Stimulating Factor (GM‐CSF)‐3928C/T and GM‐CSF(3606T⁄C) Promoter gene polymorphisms with the pathogenesis and severity of acne vulgaris: A case‐controlled study
Published in Journal of cosmetic dermatology (01-11-2021)“…Background Granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) is believed to play an important role in the development of acne vulgaris. Aim of the Work…”
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The role of microRNA-31 and microRNA-21 as regulatory biomarkers in the activation of T lymphocytes of Egyptian lupus patients
Published in Rheumatology international (01-11-2016)“…Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by familial aggregation and genetic predisposition. MicroRNAs (MiRNAs) serve as…”
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Polymorphisms at IL28B gene as predictors of viral relapse in genotype 4 Egyptian hepatitis C patients
Published in Journal of medical virology (01-03-2016)“…Chronic HCV is one of the commonest causes of chronic liver disease worldwide with about 15% of population infected in Egypt. Certain single nucleotide…”
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Study of the relation between two common cyclooxygenase 2 gene polymorphisms with risk of developing and subtypes of vitiligo in Egyptian patients
Published in Indian journal of dermatology, venereology, and leprology (01-11-2018)“…Background/Purpose: Genetic factors play an important role in the pathogenesis of vitiligo. Cyclooxygenase 2 (COX2) gene induced by ultraviolet radiation…”
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Transforming growth factor-β1 gene polymorphism in psoriasis vulgaris
Published in Clinical, cosmetic and investigational dermatology (2018)“…Increased transforming growth factor beta 1 (TGF-β1) in the epidermis and serum has been found in psoriatic patients. The mechanism for this increase remains…”
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Evaluating the association of APOA2 polymorphism with insulin resistance in adolescents
Published in Meta Gene (01-12-2014)“…265T>C SNP in the APOA-II gene promoter may be associated with obesity risk and insulin resistance (IR). This study aims to analyze the association between the…”
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