Search Results - "Ampuero, Estíbaliz"
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In Vivo Sub-chronic Treatment with Dichlorvos in Young Rats Promotes Synaptic Plasticity and Learning by a Mechanism that Involves Acylpeptide Hydrolase Instead of Acetylcholinesterase Inhibition. Correlation with Endogenous β-Amyloid Levels
Published in Frontiers in pharmacology (25-07-2017)“…Acylpeptide hydrolase (APEH) is a serine hydrolase that displays two catalytic activities, acting both as an exopeptidase toward short -acylated peptides and…”
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Editorial: Medicinal drugs, the effect on memories and beyond
Published in Frontiers in pharmacology (20-08-2024)Get full text
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The multifaceted effects of fluoxetine treatment on cognitive functions
Published in Frontiers in pharmacology (16-07-2024)“…Fluoxetine, the prototypical selective serotonin reuptake inhibitor (SSRI), is widely used to treat major depressive disorder (MDD) and a variety of other…”
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Somatostatin inhibition of fictive respiration is modulated by pH
Published in Brain research (05-11-2004)“…We studied the respiratory effects of the tetradecapeptide somatostatin (SST) upon fictive respiration using the in vitro brain stem spinal cord preparation…”
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Pathogenicity of Lupus Anti–Ribosomal P Antibodies: Role of Cross‐Reacting Neuronal Surface P Antigen in Glutamatergic Transmission and Plasticity in a Mouse Model
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-06-2015)“…Objective To assess whether autoantibodies against ribosomal P (anti‐P), which are possibly pathogenic in neuropsychiatric systemic lupus erythematosus…”
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NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB‐P, and H3K27ac
Published in Journal of cellular physiology (01-12-2017)“…Dendrite arbor growth, or dendritogenesis, is choreographed by a diverse set of cues, including the NMDA receptor (NMDAR) subunits NR2A and NR2B. While NR1NR2B…”
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Two Chronic Stress Models Based on Movement Restriction in Rats Respond Selectively to Antidepressant Drugs: Aldolase C As a Potential Biomarker
Published in The international journal of neuropsychopharmacology (01-09-2015)“…Background: Clinically depressed individuals respond to different types of antidepressants, suggesting that different neurobiological mechanisms may be…”
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Long-term fluoxetine treatment induces input-specific LTP and LTD impairment and structural plasticity in the CA1 hippocampal subfield
Published in Frontiers in cellular neuroscience (2013)“…Antidepressant drugs are usually administered for several weeks for the treatment of major depressive disorder. However, they are also prescribed in several…”
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Chronic Fluoxetine Treatment Induces Maturation-Compatible Changes in the Dendritic Arbor and in Synaptic Responses in the Auditory Cortex
Published in Frontiers in pharmacology (17-07-2019)“…Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) used to treat mood and anxiety disorders. Chronic treatment with this antidepressant drug is…”
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Evidence for TGF-β1/Nrf2 Signaling Crosstalk in a Cuprizone Model of Multiple Sclerosis
Published in Antioxidants (29-07-2024)“…Multiple sclerosis (MS) is a chronic and degenerative disease that impacts central nervous system (CNS) function. One of the major characteristics of the…”
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Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43A90V mutation display a mild reactive state and release polyP toxic to motoneurons
Published in Frontiers in cell and developmental biology (28-07-2023)“…Astrocytes play a critical role in the maintenance of a healthy central nervous system and astrocyte dysfunction has been implicated in various…”
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Status epilepticus induces region-specific changes in dendritic spines, dendritic length and TrkB protein content of rat brain cortex
Published in Brain research (30-05-2007)“…Abstract Induction of status epilepticus (SE) with kainic acid results in a large reorganization of neuronal brain circuits, a phenomenon that has been studied…”
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Superoxide generation via the NR2B‐NMDAR/RasGRF1/NOX2 pathway promotes dendritogenesis
Published in Journal of cellular physiology (01-12-2019)“…N‐methyl‐D‐aspartate receptors (NMDARs) that contain the NR2A and NR2B subunits play a critical role in neuronal plasticity and dendritogenesis…”
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Interfering of the Reelin/ApoER2/PSD95 Signaling Axis Reactivates Dendritogenesis of Mature Hippocampal Neurons
Published in Journal of cellular physiology (01-05-2017)“…Reelin, an extracellular glycoprotein secreted in embryonic and adult brain, participates in neuronal migration and neuronal plasticity. Extensive evidence…”
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PSD95 regulates morphological development of adult-born granule neurons in the mouse hippocampus
Published in Journal of chemical neuroanatomy (01-07-2019)“…•Neuronal differentiation in adult dentate gyrus occurs despite PSD95 knockdown.•PSD95 knockdown does not affect migration of adult-born granule neurons.•PSD95…”
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Prenatal fluoxetine impairs non-hippocampal but not hippocampal memory in adult male rat offspring
Published in Neuropharmacology (01-10-2021)“…Fluoxetine is often prescribed to treat depression during pregnancy. Rodent studies have shown that fluoxetine exposure during early development can induce…”
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Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling
Published in Frontiers in cellular neuroscience (09-06-2015)“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which pathogenesis and death of motor neurons are triggered by non-cell-autonomous…”
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Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice
Published in Clinical epigenetics (18-02-2020)“…Hexanucleotide repeat expansions of the G C motif in a non-coding region of the C9ORF72 gene are the most common genetic cause of amyotrophic lateral sclerosis…”
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Repetitive fluoxetine treatment affects long-term memories but not learning
Published in Behavioural brain research (15-06-2013)“…•Fluoxetine treatment specifically impairs long-term memory.•Fluoxetine treatment does not affect learning.•Fluoxetine withdrawal restores impairment in…”
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In vitro approach to the chemical drive of breathing
Published in Biological research (2001)“…Since its introduction two decades ago, the isolated brain stem-spinal cord preparation of neonatal rodents has been the preferred method used to reveal the…”
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