Search Results - "Ampt, Kirsten"

Interpretation and visualization of non-linear data fusion in kernel space: study on metabolomic characterization of progression of multiple sclerosis by Smolinska, Agnieszka, Blanchet, Lionel, Coulier, Leon, Ampt, Kirsten A M, Luider, Theo, Hintzen, Rogier Q, Wijmenga, Sybren S, Buydens, Lutgarde M C

“…In the last decade data fusion has become widespread in the field of metabolomics. Linear data fusion is performed most commonly. However, many data display…”
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Fusion of metabolomics and proteomics data for biomarkers discovery: case study on the experimental autoimmune encephalomyelitis by Blanchet, Lionel, Smolinska, Agnieszka, Attali, Amos, Stoop, Marcel P, Ampt, Kirsten A M, van Aken, Hans, Suidgeest, Ernst, Tuinstra, Tinka, Wijmenga, Sybren S, Luider, Theo, Buydens, Lutgarde M C

“…Analysis of Cerebrospinal Fluid (CSF) samples holds great promise to diagnose neurological pathologies and gain insight into the molecular background of these…”
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A Microfluidic High-Resolution NMR Flow Probe by Bart, Jacob, Kolkman, Ard J, Oosthoek-de Vries, Anna Jo, Koch, Kaspar, Nieuwland, Pieter J, Janssen, Hans (J. W. G.), van Bentum, Jan (P. J. M.), Ampt, Kirsten A. M, Rutjes, Floris P. J. T, Wijmenga, Sybren S, Gardeniers, Han (J. G. E.), Kentgens, Arno P. M

“…A microfluidic high-resolution NMR flow probe based on a novel stripline detector chip is demonstrated. This tool is invaluable for the in situ monitoring of…”
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Determination and identification of estrogenic compounds generated with biosynthetic enzymes using hyphenated screening assays, high resolution mass spectrometry and off-line NMR by de Vlieger, Jon S.B., Kolkman, Ard J., Ampt, Kirsten A.M., Commandeur, Jan N.M., Vermeulen, Nico P.E., Kool, Jeroen, Wijmenga, Sybren S., Niessen, Wilfried M.A., Irth, Hubertus, Honing, Maarten

“…This paper describes the determination and identification of active and inactive estrogenic compounds produced by biosynthetic methods. A hyphenated screening…”
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Quantitative Proteomics and Metabolomics Analysis of Normal Human Cerebrospinal Fluid Samples by Stoop, Marcel P., Coulier, Leon, Rosenling, Therese, Shi, Shanna, Smolinska, Agnieszka M., Buydens, Lutgarde, Ampt, Kirsten, Stingl, Christoph, Dane, Adrie, Muilwijk, Bas, Luitwieler, Ronald L., Sillevis Smitt, Peter A.E., Hintzen, Rogier Q., Bischoff, Rainer, Wijmenga, Sybren S., Hankemeier, Thomas, van Gool, Alain J., Luider, Theo M.

“…The analysis of cerebrospinal fluid (CSF) is used in biomarker discovery studies for various neurodegenerative central nervous system (CNS) disorders. However,…”
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Thermodynamics and NMR studies on Duck, Heron and Human HBV encapsidation signals by Girard, Frederic C., Ottink, Otmar M., Ampt, Kirsten A.M., Tessari, Marco, Wijmenga, Sybren S.

“…Hepatitis B virus (HBV) replication is initiated by binding of its reverse transcriptase (P) to the apical stem-loop (AL) and primer loop (PL) of epsilon, a…”
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Simultaneous analysis of plasma and CSF by NMR and hierarchical models fusion by Smolinska, Agnieszka, Posma, Joram M., Blanchet, Lionel, Ampt, Kirsten A. M., Attali, Amos, Tuinstra, Tinka, Luider, Theo, Doskocz, Marek, Michiels, Paul J., Girard, Frederic C., Buydens, Lutgarde M. C., Wijmenga, Sybren S.

“…Because cerebrospinal fluid (CSF) is the biofluid which interacts most closely with the central nervous system, it holds promise as a reporter of neurological…”
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Fluorine detected 2D NMR experiments for the practical determination of size and sign of homonuclear F–F and heteronuclear C–F multiple bond J-coupling constants in multiple fluorinated compounds by Aspers, Ruud L.E.G., Ampt, Kirsten A.M., Dvortsak, Peter, Jaeger, Martin, Wijmenga, Sybren S.

“…[Display omitted] •Fluorine-detected homo- and heteronuclear NMR.•F2-site-selective heteronuclear XLOC and HMQC.•Determination of FF- and CF-couplings of…”
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The Unstable Part of the Apical Stem of Duck Hepatitis B Virus Epsilon Shows Enhanced Base Pair Opening but Not Pico- to Nanosecond Dynamics and Is Essential for Reverse Transcriptase Binding by Ampt, Kirsten A. M, van der Werf, Ramon M, Nelissen, Frank H. T, Tessari, Marco, Wijmenga, Sybren S

“…Hepatitis B virus (HBV) replication starts with binding of reverse transcriptase (RT) to the apical stem−loop region of epsilon, a conserved element of the RNA…”
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Application of fluorine NMR for structure identification of steroids by Ampt, Kirsten A. M., Aspers, Ruud L. E. G., Jaeger, Martin, Geutjes, Pepijn E. T. J., Honing, Maarten, Wijmenga, Sybren S.

“…Fluorinated steroids were examined using 1D and 2D homo‐ and heteronuclear 19F NMR, such as 19F1H and 19F13C. The utilization of fluorine NMR accounted for…”
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Photochemical Isomerization of N-Heterocyclic Carbene Ruthenium Hydride Complexes:  In situ Photolysis, Parahydrogen, and Computational Studies by Ampt, Kirsten A. M, Burling, Suzanne, Donald, Steven M. A, Douglas, Susie, Duckett, Simon B, Macgregor, Stuart A, Perutz, Robin N, Whittlesey, Michael K

“…Low-temperature UV irradiation of the N-heterocyclic carbene complex Ru(IEt2Me2)(PPh3)2(CO)H2 (IEt2Me2 = 1,3-bis(ethyl)-4,5-dimethylimidazol-2-ylidene) leads…”
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Determination of size and sign of hetero-nuclear coupling constants from 2D 19F–13C correlation spectra by Ampt, Kirsten A.M., Aspers, Ruud L.E.G., Dvortsak, Peter, van der Werf, Ramon M., Wijmenga, Sybren S., Jaeger, Martin

“…[Display omitted] ► 2D 19F–13C correlation experiments have a high information content. ► Different decoupling schemes facilitate understanding of observed…”
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Quantitative proteomics and metabolomics analysis of normal human cerebrospinal fluid samples by Stoop, Marcel P, Coulier, Leon, Rosenling, Therese, Shi, Shanna, Smolinska, Agnieszka M, Buydens, Lutgarde, Ampt, Kirsten, Stingl, Christoph, Dane, Adrie, Muilwijk, Bas, Luitwieler, Ronald L, Sillevis Smitt, Peter A E, Hintzen, Rogier Q, Bischoff, Rainer, Wijmenga, Sybren S, Hankemeier, Thomas, van Gool, Alain J, Luider, Theo M

“…The analysis of cerebrospinal fluid (CSF) is used in biomarker discovery studies for various neurodegenerative central nervous system (CNS) disorders. However,…”
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Fluorine detected 2D NMR experiments for the practical determination of size and sign of homonuclear FaF and heteronuclear CaF multiple bond J-coupling constants in multiple fluorinated compounds by Aspers, Ruud, Ampt, Kirsten, Dvortsak, Peter, Jaeger, Martin, Wijmenga, Sybren

“…The use of fluorine in molecules obtained from chemical synthesis has become increasingly important within the pharmaceutical and agricultural industry. NMR…”
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NMR and Pattern Recognition Can Distinguish Neuroinflammation and Peripheral Inflammation by Smolinska, Agnieszka, Attali, Amos, Blanchet, Lionel, Ampt, Kirsten, Tuinstra, Tinka, van Aken, Hans, Suidgeest, Ernst, van Gool, Alain J, Luider, Theo, Wijmenga, Sybren S, Buydens, Lutgarde M.C

“…Multiple Sclerosis (MScl) is a neurodegenerative disease of the CNS, associated with chronic neuroinflammation. Cerebrospinal fluid (CSF), being in closest…”
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