Search Results - "Amour, Augustin J"

The identification of β-hydroxy carboxylic acids as selective MMP-12 inhibitors by Holmes, Ian P., Gaines, Simon, Watson, Steve P., Lorthioir, Olivier, Walker, Adam, Baddeley, Suzanne J., Herbert, Shane, Egan, Danielle, Convery, Máire A., Singh, Onkar M.P., Gross, Jeffrey W., Strelow, John M., Smith, Robert H., Amour, Augustin J., Brown, David, Martin, Stephen L.

“…A new class of selective MMP-12 inhibitors have been identified via high throughput screening. Crystallization with MMP-12 confirmed the mode of binding and…”
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Antithrombotic Potential of GW813893: A Novel, Orally Active, Active-site Directed Factor Xa Inhibitor by Abboud, Melanie A, Needle, Saul J, Burns-Kurtis, Cynthia L, Valocik, Richard E, Koster, Paul F, Amour, Augustin J, Chan, Chuen, Brown, David, Chaudry, Laiq, Zhou, Ping, Patikis, Angela, Patel, Champa, Pateman, Anthony J, Young, Rob J, Watson, Nigel S, Toomey, John R

“…BACKGROUND:Factor Xa (FXa) has been a target of considerable interest for drug development efforts aimed at suppressing thrombosis. In this report, a new…”
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