Search Results - "Amos, Linda A"

Structure of a Bacterial Dynamin-like Protein Lipid Tube Provides a Mechanism For Assembly and Membrane Curving by Low, Harry H., Sachse, Carsten, Amos, Linda A., Löwe, Jan

“…Proteins of the dynamin superfamily mediate membrane fission, fusion, and restructuring events by polymerizing upon lipid bilayers and forcing regions of high…”
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Prokaryotic origin of the actin cytoskeleton by van den Ent, Fusinita, Amos, Linda A, Löwe, Jan

“…It was thought until recently that bacteria lack the actin or tubulin filament networks that organize eukaryotic cytoplasm. However, we show here that the…”
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Filament structure of bacterial tubulin homologue TubZ by Aylett, Christopher H. S., Wang, Qing, Michie, Katharine A., Amos, Linda A., Löwe, Jan, Harrison, Stephen C.

“…Low copy number plasmids often depend on accurate partitioning systems for their continued survival. Generally, such systems consist of a centromere-like…”
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Mal3, the Schizosaccharomyces pombe homolog of EB1, changes the microtubule lattice by des Georges, Amédée, Cross, Robert A, Amos, Linda A, Katsuki, Miho, Drummond, Douglas R, Osei, Michael

“…In vitro , pure tubulin assembles into B-lattice microtubules, in which lateral αα and ββ contacts between tubulin heterodimers predominate. Mal3, a homolog of…”
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Crystal structure of the bacterial cell-division protein FtsZ by Löwe, Jan, Amos, Linda A

“…Bacterial cell division ends with septation, the constriction of the cell wall and cell membranes that leads to the formation of two daughter cells,. During…”
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What tubulin drugs tell us about microtubule structure and dynamics by Amos, Linda A.

“…A wide range of small molecules, including alkaloids, macrolides and peptides, bind to tubulin and disturb microtubule assembly dynamics. Some agents inhibit…”
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MinCD cell division proteins form alternating copolymeric cytomotive filaments by Ghosal, Debnath, Trambaiolo, Daniel, Amos, Linda A., Löwe, Jan

“…During bacterial cell division, filaments of the tubulin-like protein FtsZ assemble at midcell to form the cytokinetic Z-ring. Its positioning is regulated by…”
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Evolution of cytomotive filaments: The cytoskeleton from prokaryotes to eukaryotes by Löwe, Jan, Amos, Linda A.

“…The basic features of the active filaments that use nucleotide hydrolysis to organise the cytoplasm are remarkably similar in the majority of all cells and are…”
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Structural/functional homology between the bacterial and eukaryotic cytoskeletons by Amos, Linda A, van den Ent, Fusinita, Löwe, Jan

“…Structural proteins are now known to be as necessary for controlling cell division and cell shape in prokaryotes as they are in eukaryotes. Bacterial ParM and…”
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The tektin family of microtubule-stabilizing proteins by Amos, Linda A

“…Tektins are insoluble alpha-helical proteins essential for the construction of cilia and flagella and are found throughout the eukaryotes apart from higher…”
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Why do brains need tau (MAPT)? by Amos, Linda A.

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CetZ tubulin-like proteins control archaeal cell shape by Duggin, Iain G., Aylett, Christopher H. S., Walsh, James C., Michie, Katharine A., Wang, Qing, Turnbull, Lynne, Dawson, Emma M., Harry, Elizabeth J., Whitchurch, Cynthia B., Amos, Linda A., Löwe, Jan

“…The structure and function of CetZ, a protein related to both tubulin and FtsZ (the bacterial homologue of tubulin) from the archaeon Haloferax volcanii , is…”
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Microtubule structure and its stabilisation by Amos, Linda A

“…Microtubules are designed to be dynamically unstable. GTP hydrolysis converts an initially stable polymeric structure into an unstable one in which strain at…”
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High-resolution structural analysis of the kinesin-microtubule complex by electron cryo-microscopy by Hirose, Keiko, Amos, Linda A

“…To understand the interaction of kinesin and microtubules, it is necessary to study the three-dimensional (3D) structures of the kinesin-microtubule complex at…”
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Interaction of tau protein with the dynactin complex by Magnani, Enrico, Fan, Juan, Gasparini, Laura, Golding, Matthew, Williams, Meredith, Schiavo, Giampietro, Goedert, Michel, Amos, Linda A, Spillantini, Maria Grazia

“…Tau is an axonal microtubule‐associated protein involved in microtubule assembly and stabilization. Mutations in Tau cause frontotemporal dementia and…”
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Tubulin and FtsZ form a distinct family of GTPases by Nogales, Eva, Downing, Kenneth H, Amos, Linda A, Löwe, Jan

“…Tubulin and FtsZ share a common fold of two domains connected by a central helix. Structure-based sequence alignment shows that common residues localize in the…”
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The subtle allostery of microtubule dynamics by Amos, Linda A, Löwe, Jan

“…New high-resolution structures of microtubules reveal that GTP and taxol each stimulate microtubule assembly by inducing straight protofilaments and promoting…”
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Structure of the Tubulin/FtsZ-Like Protein TubZ from Pseudomonas Bacteriophage ΦKZ by Aylett, Christopher H.S., Izoré, Thierry, Amos, Linda A., Löwe, Jan

“…Pseudomonas ΦKZ-like bacteriophages encode a group of related tubulin/FtsZ-like proteins believed to be essential for the correct centring of replicated…”
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Repeat motifs of tau bind to the insides of microtubules in the absence of taxol by Kar, Santwana, Fan, Juan, Smith, Michael J., Goedert, Michel, Amos, Linda A.

“…The tau family of microtubule‐associated proteins has a microtubule‐binding domain which includes three or four conserved sequence repeats. Pelleting assays…”
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Articulated Tubes by Amos, Linda A.

“…High quality images of microtubules with different numbers of protofilaments, and hence substantially different curvatures, have been reconstructed from…”
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