Search Results - "Amos, Claire L"

Mind the gap? The platform trial as a working environment by Morrell, Liz, Hordern, Joshua, Brown, Louise, Sydes, Matthew R, Amos, Claire L, Kaplan, Richard S, Parmar, Mahesh K B, Maughan, Timothy S

“…Trials have become bigger and more complicated due to the complexity introduced by biomarker stratification, and the advent of multi-arm multi-stage trials,…”
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Intracellular Domain of Brain Endothelial Intercellular Adhesion Molecule-1 Is Essential for T Lymphocyte-Mediated Signaling and Migration by Greenwood, John, Amos, Claire L, Walters, Claire E, Couraud, Pierre-Olivier, Lyck, Ruth, Engelhardt, Britta, Adamson, Peter

“…To examine the role of the ICAM-1 C-terminal domain in transendothelial T lymphocyte migration and ICAM-1-mediated signal transduction, mutant human (h)ICAM-1…”
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Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial by Parker, Christopher C, James, Nicholas D, Brawley, Christopher D, Clarke, Noel W, Hoyle, Alex P, Ali, Adnan, Ritchie, Alastair W S, Attard, Gerhardt, Chowdhury, Simon, Cross, William, Dearnaley, David P, Gillessen, Silke, Gilson, Clare, Jones, Robert J, Langley, Ruth E, Malik, Zafar I, Mason, Malcolm D, Matheson, David, Millman, Robin, Russell, J Martin, Thalmann, George N, Amos, Claire L, Alonzi, Roberto, Bahl, Amit, Birtle, Alison, Din, Omar, Douis, Hassan, Eswar, Chinnamani, Gale, Joanna, Gannon, Melissa R, Jonnada, Sai, Khaksar, Sara, Lester, Jason F, O'Sullivan, Joe M, Parikh, Omi A, Pedley, Ian D, Pudney, Delia M, Sheehan, Denise J, Srihari, Narayanan Nair, Tran, Anna T H, Parmar, Mahesh K B, Sydes, Matthew R

“…Based on previous findings, we hypothesised that radiotherapy to the prostate would improve overall survival in men with metastatic prostate cancer, and that…”
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Ezrin and moesin co-localise with ICAM-1 in brain endothelial cells but are not directly associated by Romero, Ignacio A, Amos, Claire L, Greenwood, John, Adamson, Peter

“…The precise mechanism by which ICAM-1 transduces signals from adherent lymphocytes remains elusive. The ERM proteins ezrin and moesin were found to strongly…”
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Radiotherapy to the prostate for men with metastatic prostate cancer in the UK and Switzerland: Long-term results from the STAMPEDE randomised controlled trial by Chris C Parker, Nicholas D James, Christopher D Brawley, Noel W Clarke, Adnan Ali, Claire L Amos, Gerhardt Attard, Simon Chowdhury, Adrian Cook, William Cross, David P Dearnaley, Hassan Douis, Duncan C Gilbert, Clare Gilson, Silke Gillessen, Alex Hoyle, Rob J Jones, Ruth E Langley, Zafar I Malik, Malcolm D Mason, David Matheson, Robin Millman, Mary Rauchenberger, Hannah Rush, J Martin Russell, Hannah Sweeney, Amit Bahl, Alison Birtle, Lisa Capaldi, Omar Din, Daniel Ford, Joanna Gale, Ann Henry, Peter Hoskin, Mohammed Kagzi, Anna Lydon, Joe M O'Sullivan, Sangeeta A Paisey, Omi Parikh, Delia Pudney, Vijay Ramani, Peter Robson, Narayanan Nair Srihari, Jacob Tanguay, Mahesh K B Parmar, Matthew R Sydes, STAMPEDE Trial Collaborative Group

“…BackgroundSTAMPEDE has previously reported that radiotherapy (RT) to the prostate improved overall survival (OS) for patients with newly diagnosed prostate…”
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Docetaxel for Nonmetastatic Prostate Cancer: Long-Term Survival Outcomes in the STAMPEDE Randomized Controlled Trial by James, Nicholas D, Ingleby, Fiona C, Clarke, Noel W, Amos, Claire L, Attard, Gerhardt, Brawley, Christopher D, Chowdhury, Simon, Cross, William, Dearnaley, David P, Gilbert, Duncan C, Gillessen, Silke, Jones, Robert J, Langley, Ruth E, Macnair, Archie, Malik, Zafar I, Mason, Malcolm D, Matheson, David J, Millman, Robin, Parker, Chris C, Rush, Hannah L, Russell, J Martin, Au, Carly, Ritchie, Alastair W S, Mestre, Ricardo Pereira, Ahmed, Imtiaz, Birtle, Alison J, Brock, Susannah J, Das, Prantik, Ford, Victoria A, Gray, Emma K, Hughes, Robert J, Manetta, Caroline B, McLaren, Duncan B, Nikapota, Ashok D, O'Sullivan, Joe M, Perna, Carla, Peedell, Clive, Protheroe, Andrew S, Sundar, Santhanam, Tanguay, Jacob S, Tolan, Shaun P, Wagstaff, John, Wallace, Jan B, Wylie, James P, Zarkar, Anjali, Parmar, Mahesh K B, Sydes, Matthew R

“…STAMPEDE previously reported adding upfront docetaxel improved overall survival for prostate cancer patients starting long-term androgen deprivation therapy…”
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Intracellular domain of brain endothelial ICAM-1 is essential for T-lymphocyte-mediated signalling and migration1 by Greenwood, John, Amos, Claire L., Walters, Claire E., Couraud, Pierre-Olivier, Lyck, Ruth, Engelhardt, Britta, Adamson, Peter

“…In order to examine the role of the ICAM-1 C-terminal domain in mediating transendothelial T-lymphocyte migration and ICAM-1 mediated signal transduction…”
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THE ROLE OF CASPASE 3 AND BclxLIN THE ACTION OF INTERLEUKIN 7 (IL-7): A SURVIVAL FACTOR IN ACTIVATED HUMAN T CELLS by Amos, Claire L., Woetmann, Anders, Nielsen, Mette, Geisler, Carsten, Ødum, Niels, Brown, Barry L., Dobson, Pauline R.M.

“…The effects of interleukin 7 (IL-7) on apoptosis in interleukin 2 (IL-2)-dependent, activated, primary, human T lymphocytes (hT cells) was examined. IL-7 (like…”
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