Search Results - "Amorino, GP"
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A Selective Cyclooxygenase-2 Inhibitor, NS-398, Enhances the Effect of Radiation in Vitro and in Vivo Preferentially on the Cells That Express Cyclooxygenase-2
Published in Clinical cancer research (01-10-2001)“…It has been proposed that Cyclooxygenase (COX)-2 inhibitors may be able to enhance the effects of chemotherapeutic or radiation treatment; however, currently…”
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Neuroendocrine cells in prostate cancer
Published in Critical reviews in eukaryotic gene expression (2004)“…Neuroendocrine (NE) cells are found in prostate tumors, and their incidence is considered a promising prognostic indicator for the development of…”
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3
EGFRvIII-mediated radioresistance through a strong cytoprotective response
Published in Oncogene (28-08-2003)“…The constitutively active, truncated epidermal growth factor receptor EGFRvIII lacks the ability of EGF binding due to a deletion of the NH(2)-terminal domain…”
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Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells
Published in Molecular biology of the cell (01-07-2002)“…Ionizing radiation (1-5 Gy) activates the epidermal growth factor receptor (EGFR), a major effector of the p42/44 mitogen-activated protein kinase (MAPK)…”
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Dominant-negative cAMP-responsive Element-binding Protein Inhibits Proliferating Cell Nuclear Antigen and DNA Repair, Leading to Increased Cellular Radiosensitivity
Published in The Journal of biological chemistry (08-08-2003)“…Selective inhibition of the epidermal growth factor receptor or mitogen-activated protein kinase (MAPK) results in radiosensitization of cancer cells. One…”
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Interactions of monocytic cells with human endothelial cells stimulate monocytic metalloproteinase production
Published in The American journal of pathology (01-01-1998)“…Monocyte-endothelial cell interactions play an important role in the early stages of atherosclerosis, and it is hypothesized that regulation of…”
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The novel taxane analogs, BMS-184476 and BMS-188797, potentiate the effects of radiation therapy in vitro and in vivo against human lung cancer cells
Published in International journal of radiation oncology, biology, physics (01-10-2001)“…To evaluate the novel taxane analogs, BMS-184476 and BMS-188797, as potential radiosensitizers in vitro and in vivo. Human H460 lung cancer cells were…”
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Radiation enhancement by the combined use of topoisomerase I inhibitors, RFS-2000 or CPT-11, and topoisomerase II inhibitor etoposide in human lung cancer cells
Published in Radiotherapy and oncology (01-01-2002)“…We have tested the camptothecin analogs, RFS-2000 or CPT-11, in combination with both etoposide and ionizing radiation in vitro to examine the radiation…”
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Enhancement of Radiation Effects In Vitro by the Estrogen Metabolite 2-Methoxyestradiol
Published in Radiation research (01-04-2000)“…Amorino, G. P., Freeman, M. L. and Choy, H. Enhancement of Radiation Effects In Vitro by the Estrogen Metabolite 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME)…”
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Enhancement of Tumor Oxygenation and Radiation Response by the Allosteric Effector of Hemoglobin, RSR13
Published in Radiation research (01-09-2001)“…Amorino, G. P., Lee, H., Holburn, G. E., Paschal, C. B., Hercules, S. K., Shyr, Y., Steffen, R. P. and Choy, H. Enhancement of Tumor Oxygenation and Radiation…”
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Radiopotentiation by the oral platinum agent, JM216: role of repair inhibition
Published in International journal of radiation oncology, biology, physics (01-05-1999)“…To test for in vitro radiopotentiation by the orally-administered platinum (IV) complex, JM216; to compare these results to cisplatin and carboplatin; and to…”
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Preclinical evaluation of the orally active camptothecin analog, RFS-2000 (9-nitro-20(S)-camptothecin) as a radiation enhancer
Published in International journal of radiation oncology, biology, physics (01-05-2000)“…To test for enhancement of radiation effects in vitro and in vivo by the orally administered camptothecin derivative, 9-nitrocamptothecin (RFS-2000); to study…”
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Combined effects of the orally active cisplatin analog, JM216, and radiation in antitumor therapy
Published in Cancer chemotherapy and pharmacology (2000)“…We evaluated the orally administered platinum agent, JM216, in combination with ionizing radiation both in vivo and in vitro against human tumor cells. H460…”
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Heat-Induced Changes in Intracellular Sodium and Membrane Potential: Lack of a Role in Cell Killing and Thermotolerance
Published in Radiation research (01-09-1996)“…Hyperthermia induces transient changes in intracellular free sodium levels and membrane potential. The possible role of these changes in cell killing by…”
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Effects of hyperthermia on intracellular chloride
Published in The Journal of membrane biology (01-08-1996)“…Hyperthermia induces transient changes in [Na+]i and [K+]i in mammalian cells. Since Cl- flux is coupled with Na+ and K+ in several processes, including cell…”
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Enhancement of radiation effects by combined docetaxel and carboplatin treatment in vitro
Published in Radiation oncology investigations (1999)“…This study was designed to evaluate the combination of docetaxel (Taxotere) and carboplatin for radiopotentiation in vitro. H460 human lung carcinoma cells…”
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Intracellular Na+ measurements using sodium green tetraacetate with flow cytometry
Published in Cytometry (New York, N.Y.) (01-11-1995)“…Intracellular sodium concentration ([Na+]i) can be measured using SBFI with image analysis or spectrofluorometry. However, SBFI cannot be used with most flow…”
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