Search Results - "Amorini, M"
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Modulation of Pro-Oxidant and Pro-Inflammatory Activities of M1 Macrophages by the Natural Dipeptide Carnosine
Published in International journal of molecular sciences (25-01-2020)“…Carnosine is a natural endogenous dipeptide widely distributed in mammalian tissues, existing at particularly high concentrations in the muscles and brain and…”
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Ultra-sensitive solid-phase Microextraction–Gas Chromatography–Mass spectrometry determination of polycyclic aromatic hydrocarbons in snow samples using a deep cavity BenzoQxCavitand
Published in Chemosphere (Oxford) (01-09-2022)“…A very sensitive and selective solid-phase microextraction-gas chromatography-mass spectrometry method based on the use of a deep cavity BenzoQxCavitand as…”
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3
MacroH2A1.1 as a crossroad between epigenetics, inflammation and metabolism of mesenchymal stromal cells in myelodysplastic syndromes
Published in Cell death & disease (18-10-2023)“…Ineffective hematopoiesis is a hallmark of myelodysplastic syndromes (MDS). Hematopoietic alterations in MDS patients strictly correlate with microenvironment…”
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Carnosine Decreases PMA-Induced Oxidative Stress and Inflammation in Murine Macrophages
Published in Antioxidants (06-08-2019)“…Carnosine is an endogenous dipeptide composed of β-alanine and L-histidine. This naturally occurring molecule is present at high concentrations in several…”
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Lung Surfactant Decreases Biochemical Alterations and Oxidative Stress Induced by a Sub-Toxic Concentration of Carbon Nanoparticles in Alveolar Epithelial and Microglial Cells
Published in International journal of molecular sciences (07-03-2021)“…Carbon-based nanomaterials are nowadays attracting lots of attention, in particular in the biomedical field, where they find a wide spectrum of applications,…”
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Clobetasol promotes neuromuscular plasticity in mice after motoneuronal loss via sonic hedgehog signaling, immunomodulation and metabolic rebalancing
Published in Cell death & disease (16-06-2021)“…Motoneuronal loss is the main feature of amyotrophic lateral sclerosis, although pathogenesis is extremely complex involving both neural and muscle cells. In…”
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The Crosstalk between GPR81/IGFBP6 Promotes Breast Cancer Progression by Modulating Lactate Metabolism and Oxidative Stress
Published in Antioxidants (29-01-2022)“…Breast cancer is the most frequent tumor and the leading cause of cancer deaths in women. In recent years, lactate metabolism and, in particular, its receptor…”
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Fructose-1,6-Bisphosphate Protects Hippocampal Rat Slices from NMDA Excitotoxicity
Published in International journal of molecular sciences (07-05-2019)“…Effects of fructose 1,6-bisphosphate (F-1,6-P2) towards -methyl-d-aspartate NMDA excitotoxicity were evaluated in rat organotypic hippocampal brain slice…”
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Biochemical Discrimination of the Down Syndrome-Related Metabolic and Oxidative/Nitrosative Stress Alterations from the Physiologic Age-Related Changes through the Targeted Metabolomic Analysis of Serum
Published in Antioxidants (20-06-2022)“…Down Syndrome (DS) is a neurodevelopmental disorder that is characterized by an accelerated aging process, frequently associated with the development of…”
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Transient alterations of creatine, creatine phosphate, N-acetylaspartate and high-energy phosphates after mild traumatic brain injury in the rat
Published in Molecular and cellular biochemistry (01-01-2010)“…In this study, the concentrations of creatine (Cr), creatine phosphate (CrP), N-acetylaspartate (NAA), ATP, ADP and phosphatidylcholine (PC) were measured at…”
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The protein kinase C activator phorbol myristate acetate decreases brain edema by aquaporin 4 downregulation after middle cerebral artery occlusion in the rat
Published in Journal of neurotrauma (01-02-2010)“…The protein kinase C activator phorbol 12-myristate 13-acetate (PMA) is known to interact with aquaporin 4 (AQP 4), a water-selective transporting protein that…”
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ILB ® Attenuates Clinical Symptoms and Serum Biomarkers of Oxidative/Nitrosative Stress and Mitochondrial Dysfunction in Patients with Amyotrophic Lateral Sclerosis
Published in Journal of personalized medicine (14-08-2021)“…Oxidative/nitrosative stress and mitochondrial dysfunction is a hallmark of amyotrophic lateral sclerosis (ALS), an invariably fatal progressive…”
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Metabolic profile of amniotic fluid as a biochemical tool to screen for inborn errors of metabolism and fetal anomalies
Published in Molecular and cellular biochemistry (01-01-2012)“…Physiologic concentration in amniotic fluid (AF) of several metabolites has not been established with certainty. In this study, we initially assayed purines,…”
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LMNA gene mutation as a model of cardiometabolic dysfunction: From genetic analysis to treatment response
Published in Diabetes & metabolism (01-06-2014)“…Abstract Aim This report highlights the metabolic, endocrine and cardiovascular comorbidities in a case of familial partial lipodystrophy (FPLD), and also…”
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Cerebrospinal fluid ATP metabolites in multiple sclerosis
Published in Multiple sclerosis (01-05-2010)“…Increased axonal energy demand and mitochondrial failure have been suggested as possible causes for axonal degeneration and disability in multiple sclerosis…”
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TLR4 and NOD2/CARD15 Genetic Polymorphisms and their Possible Role in Gastric Carcinogenesis
Published in Anticancer research (01-02-2010)“…The aim of this study was to evaluate the role of TLR4 and NOD2/CARD15 genes in gastric carcinogenesis. We investigated the allelic frequencies of TLR4 (D299G…”
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The protective effect of cyclosporin A upon N-acetylaspartate and mitochondrial dysfunction following experimental diffuse traumatic brain injury
Published in Journal of neurotrauma (01-09-2004)“…Pre- and post-injury Cyclosporin A (CsA) administration has shown neuroprotective properties by ameliorating mitochondrial damage. The aim of this study was to…”
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Cerebral oxidative stress and depression of energy metabolism correlate with severity of diffuse brain injury in rats
Published in Neurosurgery (01-03-2005)“…The combined effect of traumatic brain injury (TBI) and secondary insult on biochemical changes of cerebral tissue is not well known. For this purpose, we…”
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Serum Compounds of Energy Metabolism Impairment Are Related to Disability, Disease Course and Neuroimaging in Multiple Sclerosis
Published in Molecular neurobiology (01-11-2017)“…Multiple sclerosis (MS) is characterized by primary inflammation, demyelination, and progressive neurodegeneration. A biochemical MS feature is neuronal…”
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Non-toxic engineered carbon nanodiamond concentrations induce oxidative/nitrosative stress, imbalance of energy metabolism, and mitochondrial dysfunction in microglial and alveolar basal epithelial cells
Published in Cell death & disease (14-02-2018)“…Engineered nanoparticles are finding a wide spectrum of biomedical applications, including drug delivery and capacity to trigger cytotoxic phenomena,…”
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