Search Results - "Amorim, Inês"

Loss of eIF4E Phosphorylation Engenders Depression-like Behaviors via Selective mRNA Translation by Amorim, Inês S, Kedia, Sonal, Kouloulia, Stella, Simbriger, Konstanze, Gantois, Ilse, Jafarnejad, Seyed Mehdi, Li, Yupeng, Kampaite, Agniete, Pooters, Tine, Romanò, Nicola, Gkogkas, Christos G

“…The MAPK/ERK (mitogen-activated protein kinases/extracellular signal-regulated kinase) pathway is a cardinal regulator of synaptic plasticity, learning, and…”
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The Role of the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Neuropsychiatric Disorders by Amorim, Inês S, Lach, Gilliard, Gkogkas, Christos G

“…Protein synthesis in eukaryotic cells is a complex, multi-step and tightly regulated process. Translation initiation, the rate limiting step in protein…”
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How augmented reality media richness influences consumer behaviour by Amorim, Inês Pessoa, Guerreiro, João, Eloy, Sara, Loureiro, Sandra Maria Correia

“…The current paper explores the impact that an augmented reality shopping assistant may have on consumers’ emotional and cognitive responses, and how it would…”
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Sideroflexin 3 is an α-synuclein-dependent mitochondrial protein that regulates synaptic morphology by Amorim, Inês S, Graham, Laura C, Carter, Roderick N, Morton, Nicholas M, Hammachi, Fella, Kunath, Tilo, Pennetta, Giuseppa, Carpanini, Sarah M, Manson, Jean C, Lamont, Douglas J, Wishart, Thomas M, Gillingwater, Thomas H

“…α-Synuclein plays a central role in Parkinson's disease, where it contributes to the vulnerability of synapses to degeneration. However, the downstream…”
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Uncovering memory-related gene expression in contextual fear conditioning using ribosome profiling by Simbriger, Konstanze, Amorim, Inês S., Lach, Gilliard, Chalkiadaki, Kleanthi, Kouloulia, Stella, Jafarnejad, Seyed Mehdi, Khoutorsky, Arkady, Gkogkas, Christos G.

“…Contextual fear conditioning (CFC) in rodents is the most widely used behavioural paradigm in neuroscience research to elucidate the neurobiological mechanisms…”
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Current European flood-rich period exceptional compared with past 500 years by Blöschl, Günter, Kiss, Andrea, Viglione, Alberto, Barriendos, Mariano, Böhm, Oliver, Brázdil, Rudolf, Coeur, Denis, Demarée, Gaston, Llasat, Maria Carmen, Macdonald, Neil, Retsö, Dag, Roald, Lars, Schmocker-Fackel, Petra, Amorim, Inês, Bělínová, Monika, Benito, Gerardo, Bertolin, Chiara, Camuffo, Dario, Cornel, Daniel, Doktor, Radosław, Elleder, Líbor, Enzi, Silvia, Garcia, João Carlos, Glaser, Rüdiger, Hall, Julia, Haslinger, Klaus, Hofstätter, Michael, Komma, Jürgen, Limanówka, Danuta, Lun, David, Panin, Andrei, Parajka, Juraj, Petrić, Hrvoje, Rodrigo, Fernando S., Rohr, Christian, Schönbein, Johannes, Schulte, Lothar, Silva, Luís Pedro, Toonen, Willem H. J., Valent, Peter, Waser, Jürgen, Wetter, Oliver

“…There are concerns that recent climate change is altering the frequency and magnitude of river floods in an unprecedented way 1 . Historical studies have…”
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CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia by Schmoellerl, Johannes, Barbosa, Inês Amorim Monteiro, Eder, Thomas, Brandstoetter, Tania, Schmidt, Luisa, Maurer, Barbara, Troester, Selina, Pham, Ha Thi Thanh, Sagarajit, Mohanty, Ebner, Jessica, Manhart, Gabriele, Aslan, Ezgi, Terlecki-Zaniewicz, Stefan, Van der Veen, Christa, Hoermann, Gregor, Duployez, Nicolas, Petit, Arnaud, Lapillonne, Helene, Puissant, Alexandre, Itzykson, Raphael, Moriggl, Richard, Heuser, Michael, Meisel, Roland, Valent, Peter, Sexl, Veronika, Zuber, Johannes, Grebien, Florian

“…Fusion proteins involving Nucleoporin 98 (NUP98) are recurrently found in acute myeloid leukemia (AML) and are associated with poor prognosis. Lack of…”
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Monitoring translation in synaptic fractions using a ribosome profiling strategy by Simbriger, Konstanze, Amorim, Inês S., Chalkiadaki, Kleanthi, Lach, Gilliard, Jafarnejad, Seyed Mehdi, Khoutorsky, Arkady, Gkogkas, Christos G.

“…•Ribosome profiling in synaptosomes.•Transcriptome and translatome profiling from synaptic fractions.•Powerful tool to study local translation at the synapse…”
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Nitrogen Surplus—A Unified Indicator for Water Pollution in Europe? by Susanne Klages, Claudia Heidecke, Bernhard Osterburg, John Bailey, Irina Calciu, Clare Casey, Tommy Dalgaard, Hanna Frick, Matjaž Glavan, Karoline D’Haene, Georges Hofman, Inês Amorim Leitão, Nicolas Surdyk, Koos Verloop, Gerard Velthof

“…Pollution of ground-and surface waters with nitrates from agricultural sources poses a risk to drinking water quality and has negative impacts on the…”
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User communities: From nice-to-have to must-have by Costa, Joana, Amorim, Inês, Reis, João, Melão, Nuno

“…With Industry 5.0 already on the horizon, firms need to adapt their strategies to better cater to an increasingly demanding and sustainability-conscious…”
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Unlocking the Potential of Green Gravel Production for Efficient Kelp Restoration: How Seeding Density Affects the Development of the Golden Kelp Laminaria ochroleuca by Chemello, Silvia, Dos Santos, Inês Amorim, Sousa-Pinto, Isabel, Pereira, Tânia Ribeiro

“…Kelp forests are facing a global decline due to climate change and human-induced stressors, underlining the urgency for proactive interventions. Among the most…”
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eIF4E phosphorylation recruits β-catenin to mRNA cap and promotes Wnt pathway translation in dentate gyrus LTP maintenance by Patil, Sudarshan, Chalkiadaki, Kleanthi, Mergiya, Tadiwos F., Krimbacher, Konstanze, Amorim, Inês S., Akerkar, Shreeram, Gkogkas, Christos G., Bramham, Clive R.

“…The mRNA cap-binding protein, eukaryotic initiation factor 4E (eIF4E), is crucial for translation and regulated by Ser209 phosphorylation. However, the…”
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Translational profiling of dorsal root ganglia and spinal cord in a mouse model of neuropathic pain by Uttam, Sonali, Wong, Calvin, Amorim, Inês S, Jafarnejad, Seyed Mehdi, Tansley, Shannon N, Yang, Jieyi, Prager-Khoutorsky, Masha, Mogil, Jeffrey S, Gkogkas, Christos G, Khoutorsky, Arkady

“…Highlights • Translational landscape in DRG and spinal cord in SNI assay of neuropathic pain was established. • ERK is a central hub of both transcriptionally…”
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Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity by Kouloulia, Stella, Hallin, Erik I., Simbriger, Konstanze, Amorim, Inês S., Lach, Gilliard, Amvrosiadis, Theoklitos, Chalkiadaki, Kleanthi, Kampaite, Agniete, Truong, Vinh Tai, Hooshmandi, Mehdi, Jafarnejad, Seyed Mehdi, Skehel, Paul, Kursula, Petri, Khoutorsky, Arkady, Gkogkas, Christos G.

“…The translation initiation repressor 4E-BP2 is deamidated in the brain on asparagines N99/N102 during early postnatal brain development. This…”
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Pulmonary Actinomycosis: A Diagnostic Challenge by Ferreira, Marli, Ferreira, Luís, Amorim Pereira, Inês, Santos Silva, André, Henriques Ferreira, Inês

“…Pulmonary actinomycosis is an uncommon and challenging infectious disease with non-specific symptoms and imaging findings. The authors report a case of a…”
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Molecular neuropathology of the synapse in sheep with CLN5 Batten disease by Amorim, Inês S., Mitchell, Nadia L., Palmer, David N., Sawiak, Stephen J., Mason, Roger, Wishart, Thomas M., Gillingwater, Thomas H.

“…Aims Synapses represent a major pathological target across a broad range of neurodegenerative conditions. Recent studies addressing molecular mechanisms…”
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O(s) Tempo(s) by Amorim, Inês, Pinto, Sara, Silva, Luís Pedro

“…As proposal proponents of the thematic, the time (s), we considered relevant a broader reflection that would contribute to a cross-reading and an…”
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A Functional Survey of the Regulatory Landscape of Estrogen Receptor-Positive Breast Cancer Evolution by Barozzi, Iros, Slaven, Neil, Canale, Eleonora, Lopes, Rui, Amorim Monteiro Barbosa, Inês, Bleu, Melusine, Ivanoiu, Diana, Pacini, Claudia, Mensa', Emanuela, Chambers, Alfie, Bravaccini, Sara, Ravaioli, Sara, Győrffy, Balázs, Dieci, Maria Vittoria, Pruneri, Giancarlo, Galli, Giorgio Giacomo, Magnani, Luca

“…Only a handful of somatic alterations have been linked to endocrine therapy resistance in hormone-dependent breast cancer, potentially explaining ∼40% of…”
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A seeding-based neuronal model of tau aggregation for use in drug discovery by Amorim, Ines S, Challal, Sylvie, Cistarelli, Laetitia, Dorval, Thierry, Abjean, Laurene, Touzard, Manuelle, Arbez, Nicolas, François, Arnaud, Panayi, Fany, Jeggo, Ross, Cecon, Erika, Oishi, Atsuro, Dam, Julie, Jockers, Ralf, Machado, Patricia

“…Intracellular accumulation of tau protein is a hallmark of Alzheimer's Disease and Progressive Supranuclear Palsy, as well as other neurodegenerative disorders…”
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Historical floods of the Douro River in Porto, Portugal (1727–1799) by Alcoforado, Maria João, Silva, Luís Pedro, Amorim, Inês, Fragoso, Marcelo, Garcia, João Carlos

“…Extreme meteorological events have had devastating consequences all over the world throughout the ages. In this study, we look into the floods at the mouth of…”
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