Search Results - "Amor, Melina"

Identification of regulatory networks and crosstalk factors in brown adipose tissue and liver of a cold-exposed cardiometabolic mouse model by Amor, Melina, Diaz, Malena, Bianco, Valentina, Svecla, Monika, Schwarz, Birgit, Rainer, Silvia, Pirchheim, Anita, Schooltink, Laszlo, Mukherjee, Suravi, Grabner, Gernot F, Beretta, Giangiacomo, Lamina, Claudia, Norata, Giuseppe Danilo, Hackl, Hubert, Kratky, Dagmar

“…Activation of brown adipose tissue (BAT) has gained attention due to its ability to dissipate energy and counteract cardiometabolic diseases (CMDs). This study…”
Get full text

Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape by Reinisch, Isabel, Michenthaler, Helene, Sulaj, Alba, Moyschewitz, Elisabeth, Krstic, Jelena, Galhuber, Markus, Xu, Ruonan, Riahi, Zina, Wang, Tongtong, Vujic, Nemanja, Amor, Melina, Zenezini Chiozzi, Riccardo, Wabitsch, Martin, Kolb, Dagmar, Georgiadi, Anastasia, Glawitsch, Lisa, Heitzer, Ellen, Schulz, Tim J., Schupp, Michael, Sun, Wenfei, Dong, Hua, Ghosh, Adhideb, Hoffmann, Anne, Kratky, Dagmar, Hinte, Laura C., von Meyenn, Ferdinand, Heck, Albert J. R., Blüher, Matthias, Herzig, Stephan, Wolfrum, Christian, Prokesch, Andreas

“…In obesity, sustained adipose tissue (AT) inflammation constitutes a cellular memory that limits the effectiveness of weight loss interventions. Yet, the…”
Get full text

Loss of ABHD15 Impairs the Anti-lipolytic Action of Insulin by Altering PDE3B Stability and Contributes to Insulin Resistance by Xia, Wenmin, Pessentheiner, Ariane R., Hofer, Dina C., Amor, Melina, Schreiber, Renate, Schoiswohl, Gabriele, Eichmann, Thomas O., Walenta, Evelyn, Itariu, Bianca, Prager, Gerhard, Hackl, Hubert, Stulnig, Thomas, Kratky, Dagmar, Rülicke, Thomas, Bogner-Strauss, Juliane G.

“…Elevated circulating fatty acids (FAs) contribute to obesity-associated metabolic complications, but the mechanisms by which insulin suppresses lipolysis are…”
Get full text

Genetic deletion of MMP12 ameliorates cardiometabolic disease by improving insulin sensitivity, systemic inflammation, and atherosclerotic features in mice by Amor, Melina, Bianco, Valentina, Buerger, Martin, Lechleitner, Margarete, Vujić, Nemanja, Dobrijević, Anja, Akhmetshina, Alena, Pirchheim, Anita, Schwarz, Birgit, Pessentheiner, Ariane R, Baumgartner, Franziska, Rampitsch, Katharina, Schauer, Silvia, Klobučar, Iva, Degoricija, Vesna, Pregartner, Gudrun, Kummer, Daniel, Svecla, Monika, Sommer, Gerhard, Kolb, Dagmar, Holzapfel, Gerhard A, Hoefler, Gerald, Frank, Saša, Norata, Giuseppe Danilo, Kratky, Dagmar

“…Matrix metalloproteinase 12 (MMP12) is a macrophage-secreted protein that is massively upregulated as a pro-inflammatory factor in metabolic and vascular…”
Get full text

Impact of (intestinal) LAL deficiency on lipid metabolism and macrophage infiltration by Bianco, Valentina, Korbelius, Melanie, Vujic, Nemanja, Akhmetshina, Alena, Amor, Melina, Kolb, Dagmar, Pirchheim, Anita, Bradic, Ivan, Kuentzel, Katharina B., Buerger, Martin, Schauer, Silvia, Phan, Huyen T.T., Bulfon, Dominik, Hoefler, Gerald, Zimmermann, Robert, Kratky, Dagmar

“…To date, the only enzyme known to be responsible for the hydrolysis of cholesteryl esters and triacylglycerols in the lysosome at acidic pH is lysosomal acid…”
Get full text

Identification of matrix metalloproteinase-12 as a candidate molecule for prevention and treatment of cardiometabolic disease by Amor, M, Moreno Viedma, V, Sarabi, A, Grün, N G, Itariu, B, Leitner, L, Steiner, I, Bilban, M, Kodama, K, Butte, A J, Staffler, G, Zeyda, M, Stulnig, T M

“…Obesity is strongly associated with metabolic syndrome, a combination of risk factors that predispose to the development of the cardiometabolic diseases:…”
Get full text

Limited Alleviation of Lysosomal Acid Lipase Deficiency by Deletion of Matrix Metalloproteinase 12 by Buerger, Martin, Amor, Melina, Akhmetshina, Alena, Bianco, Valentina, Perfler, Bianca, Zebisch, Armin, Weichhart, Thomas, Kratky, Dagmar

“…Lysosomal acid lipase (LAL) is the only known enzyme that degrades cholesteryl esters and triglycerides at an acidic pH. In LAL deficiency (LAL-D),…”
Get full text

Serum Myostatin is Upregulated in Obesity and Correlates with Insulin Resistance in Humans by Amor, Melina, Itariu, Bianca K, Moreno-Viedma, Veronica, Keindl, Magdalena, Jürets, Alexander, Prager, Gerhard, Langer, Felix, Grablowitz, Viktor, Zeyda, Maximilian, Stulnig, Thomas M

“…Obesity and type 2 diabetes mellitus have reached an epidemic level, thus novel treatment concepts need to be identified. Myostatin, a myokine known for…”
Get more information