Search Results - "Amonkar, Gaurang M."

Primary culture of tracheal aspirate-derived human airway basal stem cells by Amonkar, Gaurang M., Wagner, Richard, Bankoti, Kamakshi, Shui, Jessica E., Ai, Xingbin, Lerou, Paul H.

“…Patient-specific airway basal stem cells (BSCs) can be derived from tracheal aspirate (TA) samples from intubated patients, thus providing an invaluable lung…”
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A Tracheal Aspirate-derived Airway Basal Cell Model Reveals a Proinflammatory Epithelial Defect in Congenital Diaphragmatic Hernia by Wagner, Richard, Amonkar, Gaurang M, Wang, Wei, Shui, Jessica E, Bankoti, Kamakshi, Tse, Wai Hei, High, Frances A, Zalieckas, Jill M, Buchmiller, Terry L, Zani, Augusto, Keijzer, Richard, Donahoe, Patricia K, Lerou, Paul H, Ai, Xingbin

“…Congenital diaphragmatic hernia (CDH) is characterized by incomplete closure of the diaphragm and lung hypoplasia. The pathophysiology of lung defects in CDH…”
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Activation of STAT3-mediated ciliated cell survival protects against severe infection by respiratory syncytial virus by Zhao, Caiqi, Bai, Yan, Wang, Wei, Amonkar, Gaurang M, Mou, Hongmei, Olejnik, Judith, Hume, Adam J, Mühlberger, Elke, Lukacs, Nicholas W, Fearns, Rachel, Lerou, Paul H, Ai, Xingbin

“…Respiratory syncytial virus (RSV) selectively targets ciliated cells in human bronchial epithelium and can cause bronchiolitis and pneumonia, mostly in…”
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Overactivated Epithelial NF-κB Disrupts Lung Development in Congenital Diaphragmatic Hernia by Dylong, Florentine, Riedel, Jan, Amonkar, Gaurang M, Peukert, Nicole, Lieckfeldt, Paula, Sturm, Katinka, Höxter, Benedikt, Tse, Wai Hei, Miyake, Yuichiro, Moormann, Maria, Bode, Lena Marie, Mayer, Steffi, Keijzer, Richard, Lacher, Martin, Ai, Xingbin, Gosemann, Jan-Hendrik, Wagner, Richard

“…Abnormal lung development is the main cause of morbidity and mortality in neonates with congenital diaphragmatic hernia (CDH), a common birth defect (1:2500)…”
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Airway Basal Stem Cells in COVID-19 Exhibit a Proinflammatory Signature and Impaired Mucocililary Differentiation by Bankoti, Kamakshi, Wang, Wei, Amonkar, Gaurang M, Xiong, Linjie, Shui, Jessica E, Zhao, Caiqi, Van, Eric, Mwase, Chimwemwe, Park, Jin-Ah, Mou, Hongmei, Fang, Yinshan, Que, Jianwen, Bai, Yan, Lerou, Paul H, Ai, Xingbin

“…Airway basal stem cells (BSCs) play a critical role in epithelial regeneration. Whether coronavirus disease (COVID-19) affects BSC function is unknown. Here,…”
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