Search Results - "Ammerlaan, Wim "

Fitness for purpose of stabilized stool samples for bile acid metabolite analyses by Neuberger-Castillo, Lorie, Ammerlaan, Wim, Betsou, Fay

“…Biobanks and cohort studies are increasingly utilizing chemical stabilizers to collect and store stool samples for downstream DNA-based microbiome analyses…”
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Multicenter Evaluation of Circulating Plasma MicroRNA Extraction Technologies for the Development of Clinically Feasible Reverse Transcription Quantitative PCR and Next-Generation Sequencing Analytical Work Flows by Kloten, Vera, Neumann, Martin H D, Di Pasquale, Francesca, Sprenger-Haussels, Markus, Shaffer, Jonathan M, Schlumpberger, Martin, Herdean, Andrei, Betsou, Fay, Ammerlaan, Wim, Af Hällström, Taija, Serkkola, Elina, Forsman, Tarja, Lianidou, Evi, Sjöback, Robert, Kubista, Mikael, Bender, Sebastian, Lampignano, Rita, Krahn, Thomas, Schlange, Thomas

“…In human body fluids, microRNA (miRNA) can be found as circulating cell-free miRNA (cfmiRNA), as well as secreted into extracellular vesicles (EVmiRNA). miRNAs…”
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Biospecimen Science of Blood for Peripheral Blood Mononuclear Cell (PBMC) Functional Applications by Betsou, Fay, Gaignaux, Amelie, Ammerlaan, Wim, Norris, Philip J., Stone, Mars

“…Purpose of Review Peripheral blood mononuclear cells (PBMCs) are used in a wide variety of preclinical assays. Preanalytical variations can have a devastating…”
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Mouse natural killer (NK) cells express the nerve growth factor receptor TrkA, which is dynamically regulated by Ralainirina, Natacha, Brons, Nicolaas H C, Ammerlaan, Wim, Hoffmann, Céline, Hentges, François, Zimmer, Jacques

“…Nerve growth factor (NGF) is a neurotrophin crucial for the development and survival of neurons. It also acts on cells of the immune system which express the…”
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Automatic buffy coat extraction: methodology, feasibility, optimization and validation study by Mathay, Conny, Ammerlaan, Wim, Betsou, Fay

“…Buffy coat isolation from whole blood has typically been a long, manual process. We tested and evaluated the feasibility, efficiency, and reproducibility of…”
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A Year in the Life of the EU-CardioRNA COST Action: CA17129 Catalysing Transcriptomics Research in Cardiovascular Disease by Robinson, Emma Louise, Gomes, Clarissa Pedrosa da Costa, Potočnjak, Ines, Hellemans, Jan, Betsou, Fay, de Gonzalo-Calvo, David, Stoll, Monika, Yilmaz, Mehmet Birhan, Ágg, Bence, Beis, Dimitris, Carmo-Fonseca, Maria, Enguita, Francisco J, Dogan, Soner, Tuna, Bilge G, Schroen, Blanche, Ammerlaan, Wim, Kuster, Gabriela M, Carpusca, Irina, Pedrazzini, Thierry, Emanueli, Costanza, Martelli, Fabio, Devaux, Yvan

“…The EU-CardioRNA Cooperation in Science and Technology (COST) Action is a European-wide consortium established in 2018 with 31 European country members and…”
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Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts by Paggetti, Jerome, Haderk, Franziska, Seiffert, Martina, Janji, Bassam, Distler, Ute, Ammerlaan, Wim, Kim, Yeoun Jin, Adam, Julien, Lichter, Peter, Solary, Eric, Berchem, Guy, Moussay, Etienne

“…Exosomes derived from solid tumor cells are involved in immune suppression, angiogenesis, and metastasis, but the role of leukemia-derived exosomes has been…”
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Intraindividual Temporal miRNA Variability in Serum, Plasma, and White Blood Cell Subpopulations by Ammerlaan, Wim, Betsou, Fay

“…Blood microRNAs (miRNAs) are ideal biomarkers, and blood derivatives are often collected in the scope of miRNA research projects. However, knowledge of…”
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Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows by Lampignano, Rita, Neumann, Martin H.D, Weber, Sabrina, Kloten, Vera, Herdean, Andrei, Voss, Thorsten, Groelz, Daniel, Babayan, Anna, Tibbesma, Marco, Schlumpberger, Martin, Chemi, Francesca, Rothwell, Dominic G, Wikman, Harriet, Galizzi, Jean-Pierre, Riise Bergheim, Inger, Russnes, Hege, Mussolin, Benedetta, Bonin, Serena, Voigt, Christine, Musa, Hanny, Pinzani, Pamela, Lianidou, Evi, Brady, Ged, Speicher, Michael R, Pantel, Klaus, Betsou, Fay, Schuuring, Ed, Kubista, Mikael, Ammerlaan, Wim, Sprenger-Haussels, Markus, Schlange, Thomas, Heitzer, Ellen

“…Abstract BACKGROUND In cancer patients, circulating cell-free DNA (ccfDNA) can contain tumor-derived DNA (ctDNA), which enables noninvasive diagnosis,…”
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Biospecimen Science of Blood for cfDNA Genetic Analyses by Ammerlaan, Wim, Betsou, Fay

“…Purpose of Review cfDNA is increasingly used for biomonitoring oncological diseases or pregnancy status by different genetic analyses. Uncontrolled…”
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Method Validation for Extraction of DNA from Human Stool Samples for Downstream Microbiome Analysis by Neuberger-Castillo, Lorie, Hamot, Gaël, Marchese, Monica, Sanchez, Ignacio, Ammerlaan, Wim, Betsou, Fay

“…A formal method validation for biospecimen processing in the context of accreditation in laboratories and biobanks is lacking. A previously optimized stool…”
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Blood DNA Yield but Not Integrity or Methylation Is Impacted After Long-Term Storage by Bulla, Alexandre, De Witt, Brian, Ammerlaan, Wim, Betsou, Fay, Lescuyer, Pierre

“…Collection of human whole blood for genomic DNA extraction is part of numerous clinical studies. Since DNA extraction cannot always be performed at the time of…”
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High‐dimensional immune profiles correlate with phenotypes of peanut allergy during food‐allergic reactions by Klueber, Julia, Czolk, Rebecca, Codreanu‐Morel, Françoise, Montamat, Guillem, Revets, Dominique, Konstantinou, Maria, Cosma, Antonio, Hunewald, Oliver, Skov, Per Stahl, Ammerlaan, Wim, Hilger, Christiane, Bindslev‐Jensen, Carsten, Ollert, Markus, Kuehn, Annette

“…Background Food challenges carry a burden of safety, effort and resources. Clinical reactivity and presentation, such as thresholds and symptoms, are…”
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Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID by Neves, Rui P L, Ammerlaan, Wim, Andree, Kiki C, Bender, Sebastian, Cayrefourcq, Laure, Driemel, Christiane, Koch, Claudia, Luetke-Eversloh, Merlin Verena, Oulhen, Marianne, Rossi, Elisabetta, Alix-Panabières, Catherine, Betsou, Fay, Farace, Françoise, Riethdorf, Sabine, Schlange, Thomas, Wikman, Harriet, Zamarchi, Rita, Pantel, Klaus, Terstappen, Leon W M M, Stoecklein, Nikolas H

“…Abstract Background Multiple technologies are available for detection of circulating tumor cells (CTCs), but standards to evaluate their technical performance…”
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Abstract 4281: Overcoming preanalytical variabilities for peripheral blood mononuclear cells and exosome profiling in the IMMUcan multicentre study by Mustapha, Rami, Pomella, Valentina, Vicencio, Jose, Lopez-Lastra, Silvia, Bahlawane, Christelle, Ammerlaan, Wim, Hong, Henoch S., Morfouace, Marie, Vallely-Gilroy, Caoimhe, Soumelis, Vassili, Romano, Emanuela, Tejpar, Sabine, Ng, Tony, Betsou, Fay

“…Abstract IMMUcan is a joint public-private partnership to advance our understanding of how tumors and the immune system interact and the effect of therapeutic…”
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Immunosorbent Assay Based on Recombinant Hemagglutinin Protein Produced in a High-Efficiency Mammalian Expression System for Surveillance of Measles Immunity by BOUCHE, F, AMMERLAAN, W, BERTHET, F, HOUARD, S, SCHNEIDER, F, MULLER, C. P

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Method validation for automated isolation of viable peripheral blood mononuclear cells by Hamot, Gael, Ammerlaan, Wim, Mathay, Conny, Kofanova, Olga, Betsou, Fay

“…This article is part of a series of publications providing formal method validation for biospecimen processing in the context of accreditation in laboratories…”
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The evolution and social determinants of mental health during the first wave of the COVID-19 outbreak in Luxembourg by Ribeiro, Fabiana, Schröder, Valerie E., Krüger, Rejko, Leist, Anja K.

“…•A longitudinal study analysed the mental health of the Luxembourgish population during the first confinement phase.•Women and younger groups presented a…”
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Differential miRNA and Protein Expression Reveals miR-1285, Its Targets TGM2 and CDH-1, as Well as CD166 and S100A13 as Potential New Biomarkers in Patients with Diabetes Mellitus and Pancreatic Adenocarcinoma by Kolokotronis, Theodoros, Majchrzak-Stiller, Britta, Buchholz, Marie, Mense, Vanessa, Strotmann, Johanna, Peters, Ilka, Skrzypczyk, Lea, Liffers, Sven-Thorsten, Menkene, Louise Massia, Wagner, Mathias, Glanemann, Matthias, Betsou, Fay, Ammerlaan, Wim, Schmidt, Ronny, Schröder, Christoph, Uhl, Waldemar, Braumann, Chris, Höhn, Philipp

“…Early detection of PDAC remains challenging due to the lack of early symptoms and the absence of reliable biomarkers. The aim of the present project was to…”
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Standard Peripheral Blood Mononuclear Cell Cryopreservation Selectively Decreases Detection of Nine Clinically Relevant T Cell Markers by Capelle, Christophe M, Ciré, Séverine, Ammerlaan, Wim, Konstantinou, Maria, Balling, Rudi, Betsou, Fay, Cosma, Antonio, Ollert, Markus, Hefeng, Feng Q

“…Biobanking is an operational component of various epidemiological studies and clinical trials. Although peripheral blood is routinely acquired and stored in…”
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