Search Results - "Ammar, Leila"
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Effects of cryopreservation on human sperm deoxyribonucleic acid integrity
Published in Fertility and sterility (2010)“…Objective To evaluate the effect of cryopreservation on sperm motility and viability and to assess sperm DNA fragmentation and oxidation in men undergoing…”
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2
Can leukocytospermia predict prostate cancer via its effects on mitochondrial DNA?
Published in Andrologia (01-09-2021)“…Leukocytospermia was previously reported to affect sperm quality by the production of reactive oxygen species (ROS) leading to oxidative stress (OS). In turn,…”
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3
Detection of a novel mutation in a Tunisian child with polycystic kidney disease
Published in IUBMB life (01-08-2020)“…Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common monogenic disease that has an adverse impact on the patients' health and quality of…”
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Effect of freezing–thawing process and quercetin on human sperm survival and DNA integrity
Published in Cryobiology (01-12-2012)“…We aimed in the first part of our work to study the effect of cryopreservation on the human sperm DNA integrity and the activation of caspase 3, the main…”
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A novel de novo splicing mutation c.1444‐2A>T in the TSC2 gene causes exon skipping and premature termination in a patient with tuberous sclerosis syndrome
Published in IUBMB life (01-12-2019)“…Tuberous sclerosis complex (TSC) syndrome is a neurocutaneous syndrome that affects the brain, skin, and kidneys that has an adverse impact on the patient's…”
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6
Virulence Factors in Colorectal Cancer Metagenomes and Association of Microbial Siderophores with Advanced Stages
Published in Microorganisms (Basel) (30-11-2022)“…Colorectal cancer (CRC) is a growing public health challenge, featuring a multifactorial etiology and complex host-environment interactions. Recently,…”
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Correlation between the intensity of Helicobacter pylori colonization and severity of gastritis: Results of a prospective study
Published in Helicobacter (Cambridge, Mass.) (01-08-2022)“…Helicobacter pylori infection is strongly associated with chronic gastritis and is probably the main course of chronic inflammation in the gastric mucosa…”
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The Archaeome's Role in Colorectal Cancer: Unveiling the DPANN Group and Investigating Archaeal Functional Signatures
Published in Microorganisms (Basel) (01-11-2023)“…Gut microbial imbalances are linked to colorectal cancer (CRC), but archaea's role remains underexplored. Here, using previously published metagenomic data…”
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Two novel mutations in COII and tRNA(His) mitochondrial genes in asthenozoospermic infertiles men
Published in Biochemical and biophysical research communications (18-07-2014)“…In this study we performed a systematic sequence analysis of 7 mitochondrial genes (cytochrome oxidase I, cytochrome oxidase II, cytochrome oxidase III,…”
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10
Analysis of Genetic Alterations in Tunisian Patients with Lung Adenocarcinoma
Published in Cells (Basel, Switzerland) (28-05-2019)“…The identification of the mutations that drive lung cancer have furnished new targets for the treatment of non-small cell lung cancer (NSCLC) and led to the…”
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Long-Term Outcome of Patients With Congenital Adrenal Hyperplasia Due to 21-hydroxylase Deficiency
Published in The American journal of the medical sciences (01-11-2012)“…Abstract Introduction Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting adrenal steroid synthesis. In this study, the authors…”
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Colorectal Cancer Archaeome: A Metagenomic Exploration, Tunisia
Published in Current issues in molecular biology (01-09-2023)“…Colorectal cancer (CRC) is a serious public health problem known to have a multifactorial etiology. The association between gut microbiota and CRC has been…”
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Deletion of CDY1b copy of Y chromosome CDY1 gene is a risk factor of male infertility in Tunisian men
Published in Gene (15-09-2014)“…The relationship between male infertility and microdeletions in the Y chromosome that remove multiple genes varies among countries and populations. The aim of…”
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14
Sperm quality improvement after date seed oil in vitro supplementation in spontaneous and induced oxidative stress
Published in Asian journal of andrology (01-05-2009)“…In vitro supplementation with date seed oil (DSO) can protect spermatozoa against hydrogen peroxide (H2O2)-mediated damage and can improve sperm function,…”
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Fertility outcome in male and female patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency
Published in Middle East Fertility Society journal (01-06-2014)“…To investigate fertility in a sample of Tunisian patients with congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. Tunisian bicentric…”
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A novel C-terminal truncated mutation in hCDKL5 protein causing a severe West syndrome: Comparison with previous truncated mutations and genotype/phenotype correlation
Published in International journal of developmental neuroscience (01-02-2019)“…•The novel c.2788insG mutation causes impairment of alternative splicing of exon 19 and the lack of a part of the proteasome signal which could disrupt the…”
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Variabilité inter et intra-opérateur de l’analyse des paramètres spermatiques: résultat d’un programme de contrôle de qualité
Published in The Pan African medical journal (2016)“…Introduction L’analyse du sperme est d’une importance majeure dans l’exploration de l'infertilité masculine. Afin de s’assurer de la fiabilité des résultats…”
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Haplotypes for 13 Y-chromosomal STR loci in South Tunisian population (Sfax region)
Published in Forensic science international (20-12-2006)“…Nine Y-STR loci from the “minimal haplotype” (DYS19, DYS385a/b, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393) included in Y-STR Haplotype Reference…”
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Lipid peroxidation and antioxidant enzyme activities in infertile men: correlation with semen parameter
Published in Journal of clinical laboratory analysis (2009)“…The aim of this study was to investigate the oxidative stress status and antioxidant enzyme activities in infertile men's semen and to determine their…”
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A novel m.6307A>G mutation in the mitochondrial COXI gene in asthenozoospermic infertile men
Published in Molecular reproduction and development (01-07-2013)“…SUMMARY Infertility affects 10–15% of the population, of which approximately 40% is due to male etiology and consists primarily of low sperm count…”
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