Search Results - "Amlot, Peter L."

A randomized placebo-controlled trial of a humanized monoclonal antibody to α4 integrin in active crohn's disease by Gordon, Fiona H., Lai, Clement W.Y., Hamilton, Mark I., Allison, Miles C., Srivastava, Emmanuel D., Fouweather, Marilyn G., Donoghue, Stephen, Greenlees, Carol, Subhani, Javaid, Amlot, Peter L., Pounder, Roy E.

“…Background & Aims: α4 integrins are important mediators of leukocyte migration across vascular endothelium.This pilot placebo-controlled study aimed to assess…”
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Allogeneic cytotoxic T-cell therapy for EBV-positive posttransplantation lymphoproliferative disease: results of a phase 2 multicenter clinical trial by Haque, Tanzina, Wilkie, Gwen M., Jones, Marie M., Higgins, Craig D., Urquhart, Gillian, Wingate, Phoebe, Burns, David, McAulay, Karen, Turner, Marc, Bellamy, Christopher, Amlot, Peter L., Kelly, Deirdre, MacGilchrist, Alastair, Gandhi, Maher K., Swerdlow, Anthony J., Crawford, Dorothy H.

“…We present the results of a multicenter clinical trial using Epstein-Barr virus (EBV)–specific cytotoxic T lymphocytes (CTLs) generated from EBV-seropositive…”
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A Phase I Trial of Epstein-Barr Virus Gp350 Vaccine for Children With Chronic Kidney Disease Awaiting Transplantation by REES, Lesley, TIZARD, E. Jane, TANDAY, Manjit K, WILSON, A. Douglas, MIDDELDORP, Jaap M, AMLOT, Peter L, STEVEN, Neil M, MORGAN, Andrew J, CUBITT, W. David, FINERTY, Susan, OYEWOLE-ELETU, Titilade A, OWEN, Karen, ROYED, Collin, STEVENS, Servi J, SHROFF, Rukshana C

“…BACKGROUND.: Vaccination against Epstein-Barr virus (EBV), inducing an antibody response to the envelope glycoprotein gp350, might protect EBV-negative…”
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Treatment of Epstein-Barr-virus-positive post-transplantation lymphoproliferative disease with partly HLA-matched allogeneic cytotoxic T cells by Haque, Tanzina, Wilkie, Gwen M, Taylor, Clare, Amlot, Peter L, Murad, Parvez, Iley, Angela, Dombagoda, Dilani, Britton, Kate M, Swerdlow, Anthony J, Crawford, Dorothy H

“…Epstein-Barr virus (EBV)-associated posttransplantation lymphoproliferative disease (PTLD) is a common, often fatal, complication of bone-marrow and solidorgan…”
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Incubation Phase of Acute Hepatitis B in Man: Dynamic of Cellular Immune Mechanisms by Webster, George J.M., Reignat, Stephanie, Maini, Mala K., Whalley, Simon A., Ogg, Graham S., King, Abigail, Brown, David, Amlot, Peter L., Williams, Roger, Vergani, Diego, Dusheiko, Geoffrey M., Bertoletti, Antonio

“…After hepatitis B virus (HBV) infection, liver injury and viral control have been thought to result from lysis of infected hepatocytes by virus-specific…”
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A quantitative assay for Epstein-Barr Virus-specific immunity shows interferon-gamma producing CD8+ T cells increase during immunosuppression reduction to treat posttransplant lymphoproliferative disease by Guppy, Amy E, Rawlings, Eira, Madrigal, J Alejandro, Amlot, Peter L, Barber, Linda D

“…Reduction of immunosuppression (RIS) to allow development or recovery of Epstein-Barr virus (EBV) immunity can be used to treat EBV-associated posttransplant…”
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Complete regression of posttransplant lymphoproliferative disease using partially HLA-matched Epstein Barr virus-specific cytotoxic T cells by HAQUE, Tanzina, TAYLOR, Clare, WILKIE, Gwen M, MURAD, Parvez, AMLOT, Peter L, BEATH, Sue, MCKIERNAN, Patrick J, CRAWFORD, Dorothy H

“…Adoptive immunotherapy with autologous and donor-derived cytotoxic T lymphocytes (CTL) has recently been used to treat Epstein Barr virus (EBV)-positive…”
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Establishment and characterization of a bank of cytotoxic T lymphocytes for immunotherapy of Epstein-Barr virus-associated diseases by WILKIE, Gwen M, TAYLOR, Clare, JONES, Marie M, BURNS, David M, TURNER, Marc, KILPATRICK, David, AMLOT, Peter L, CRAWFORD, Dorothy H, HAQUE, Tanzina

“…Adoptive immunotherapy using Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes (CTL) generated ex vivo can be an effective treatment of EBV-positive…”
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Reconstitution of EBV-Specific T Cell Immunity in Solid Organ Transplant Recipients by Haque, Tanzina, Amlot, Peter L, Helling, Nabeela, Thomas, J. Alero, Sweny, Paul, Rolles, Keith, Burroughs, Andrew K, Prentice, H. Grant, Crawford, Dorothy H

“…EBV-specific autologous CTL were grown in vitro from three adults (two liver transplant recipients and one patient on hemodialysis awaiting kidney…”
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Disappearance of an Epstein-Barr virus-positive post-transplant plasmacytoma with reduction of immunosuppression by Rees, Lesley, Thomas, Alero, Amlot, Peter L

“…The case of a child who had undergone kidney transplantation and then been diagnosed as Epstein-Barr virus seropositive is discussed…”
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Pharmaceutical development of immunosuppression in transplantation by Amlot, Peter L.

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Rapamycin-induced remission of Kaposi's sarcoma is not associated with expansion of cytotoxic T-lymphocyte subsets by Walsh, Stephen B, Summers, Shaun A, Amlot, Peter L, Sheaff, Michael T, Neild, Guy H

“…We present a case of post-transplantation Kaposi's sarcoma (KS) successfully treated by conversion to rapamycin. Clinical and histological resolution was…”
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Splenic dependence of the antibody response to thymus-independent (TI-2) antigens by Amlot, P L, Grennan, D, Humphrey, J H

“…The murine antibody response to T-independent (TI)-2 antigens [2,4-dinitrophenyl-Lys-Ficoll (DNP-FIC) and DNP-hydroxyethyl starch (HES)] was impaired long…”
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Clustering of missense mutations in the ataxia-telanglectasia gene in a sporadic T-cell leukaemia by Vo echovský, Igor, Luo, Liping, Dyer, Martin J.S, Catovsky, Daniel, Amlot, Peter L, Yaxley, John C, Foroni, Letizia, Hammarström, Lennart, Webster, A. David B, Yuille, Martin A.R

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Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia by VORECHOVSKY, I, LUO, L, DYER, M. J. S, CATOVSKY, D, AMLOT, P. L, YAXLEY, J. C, FORONI, L, HAMMARSTRÖM, L, WEBSTER, A. D. B, YUILLE, M. A. R

“…Ataxia-telangiectasia (A-T) is a recessive multi-system disorder caused by mutations in the ATM gene at 11q22-q23 (ref. 3). The risk of cancer, especially…”
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A Quantitative Assay for Epstein-Barr Virus-Specific Immunity Shows Interferon-y Producing CD8+ T Cells Increase During Immunosuppression Reduction to Treat Posttransplant Lymphoproliferative Disease by GUPPY, Amy E, RAWLINGS, Eira, MADRIGAL, J. Alejandro, AMLOT, Peter L, BARBER, Linda D

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Follicular dendritic cells share a membrane-bound protein with fibroblasts by Bofill, Margarita, Akbar, Arne N., Amlot, Peter L.

“…The expression of a fibroblast antigen (AS02) on a proportion of CD21+ follicular dendritic cells (FDCs) provides evidence in support of their fibroblastic…”
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Prolonged action of a chimeric interleukin-2 receptor (CD25) monoclonal antibody used in cadaveric renal transplantation by Amlot, P L, Rawlings, E, Fernando, O N, Griffin, P J, Heinrich, G, Schreier, M H, Castaigne, J P, Moore, R, Sweny, P

“…A high affinity chimeric CD25 mAb (chRFT5: SDZ CHI 621) blocking interleukin-2 binding to the interleukin-2 receptor alpha-chain was evaluated in a phase I/II…”
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Allogeneic cytotoxic T-cell therapy for EBV-positive posttransplantation lymphoproliferative disease : results of a phase 2 multicenter clinical trial. Commentary by SWINNEN, Lode J, HAQUE, Tanzina, BELLAMY, Christopher, AMLOT, Peter L, KELLY, Deirdre, MACGILCHRIST, Alastair, GANDHI, Maher K, SWERDLOW, Anthony J, CRAWFORD, Dorothy H, WILKIE, Gwen M, JONES, Marie M, HIGGINS, Craig D, URQUHART, Gillian, WINGATE, Phoebe, BURNS, David, MCAULAY, Karen, TURNER, Marc

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Somatically mutated regions of immunoglobulin on human b-cell lymphomas code for peptides that bind to autologous major histocompatibility complex class I, providing a potential target for cytotoxic T cells by GRICKS, Clair S, RAWLINGS, Eira, FORONI, Letizia, MADRIGAL, J. Alejandro, AMLOT, Peter L

“…Lymphoma-derived immunoglobulin idiotype (Id) is a well-characterized, tumor-specific antigen on B-cell malignancies. Immunotherapy using lymphoma…”
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