Search Results - "Amjad, Muhammad Wahab"

Recent advances in the design, development, and targeting mechanisms of polymeric micelles for delivery of siRNA in cancer therapy by Amjad, Muhammad Wahab, Kesharwani, Prashant, Mohd Amin, Mohd Cairul Iqbal, Iyer, Arun K.

“…Small interfering RNA (siRNA) is a relatively novel nucleic acid-based therapy to treat diseases such as cancer. Nevertheless, substantial obstacles to its…”
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Nanoparticles incorporated hydrogels for delivery of antimicrobial agents: developments and trends by Ahmad, Naveed, Bukhari, Syed Nasir Abbas, Hussain, Muhammad Ajaz, Ejaz, Hasan, Munir, Muhammad Usman, Amjad, Muhammad Wahab

“…The prevention and treatment of microbial infections is an imminent global public health concern due to the poor antimicrobial performance of the existing…”
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Discovery of potential anticancer multi-targeted ligustrazine based cyclohexanone and oxime analogs overcoming the cancer multidrug resistance by Zha, Gao-Feng, Qin, Hua-Li, Youssif, Bahaa G.M., Amjad, Muhammad Wahab, Raja, Maria Abdul Ghafoor, Abdelazeem, Ahmed H., Bukhari, Syed Nasir Abbas

“…The drug research and development nowadays is focusing on multi-target drugs. In the treatment of cancer, therapies using drugs inhibiting one numerous targets…”
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Thiolated Polymeric Hydrogels for Biomedical Applications: A Review by Younas, Farhan, Zaman, Muhammad, Aman, Waqar, Farooq, Umer, Raja, Maria Abdul Ghafoor, Amjad, Muhammad Wahab

“…Hydrogels are a three-dimensional (3D) network of hydrophilic polymers. The physical and chemical crosslinking of polymeric chains maintains the structure of…”
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Design, mechanism, delivery and therapeutics of canonical and Dicer-substrate siRNA by Raja, Maria Abdul Ghafoor, Katas, Haliza, Amjad, Muhammad Wahab

“…Upon the discovery of RNA interference (RNAi), canonical small interfering RNA (siRNA) has been recognized to trigger sequence-specific gene silencing. Despite…”
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Covalent Organic Frameworks (COFs) as Multi-Target Multifunctional Frameworks by Bukhari, Syed Nasir Abbas, Ahmed, Naveed, Amjad, Muhammad Wahab, Hussain, Muhammad Ajaz, Elsherif, Mervat A, Ejaz, Hasan, Alotaibi, Nasser H

“…Covalent organic frameworks (COFs), synthesized from organic monomers, are porous crystalline polymers. Monomers get attached through strong covalent bonds to…”
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Discovery of Novel Tetramethylpyrazine Containing Chalcone Derivatives as Anti-Inflammatory Agents by Bukhari, Syed Nasir Abbas, Abdelgawad, Mohamed Abdelwahab, Amjad, Muhammad Wahab, Munir, Muhammad Usman, Sheikh, Fatima Akbar

“…Chalcones are precursors of flavonoids and exhibit a broad spectrum of pharmacological activity. As anti-inflammatory agents, two series of chalcone…”
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Synthesis and mechanistic studies of curcumin analog‐based oximes as potential anticancer agents by Qin, Hua‐Li, Leng, Jing, Youssif, Bahaa G. M., Amjad, Muhammad Wahab, Raja, Maria Abdul Ghafoor, Hussain, Muhammad Ajaz, Hussain, Zahid, Kazmi, Syeda Naveed, Bukhari, Syed Nasir Abbas

“…The incidence of cancer can be decreased by chemoprevention using either natural or synthetic agents. Apart from synthetic compounds, numerous natural products…”
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Solid Lipid Nanoparticles of Mycophenolate Mofetil: An Attempt to Control the Release of an Immunosuppressant by Iqbal, Asma, Zaman, Muhammad, Wahab Amjad, Muhammad, Adnan, Sharjeel, Abdul Ghafoor Raja, Maria, Haider Rizvi, Syed Farhan, Mustafa, Mian Waqar, Farooq, Umer, Abbas, Ghulam, Shah, Shahid

“…Organ transplantation is a critically important procedure, which requires immune modulation by using immunosuppressants. Development of nanoparticles is an…”
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Synthesis, Characterization, and Biological Evaluation of Meldrum's Acid Derivatives: Dual Activity and Molecular Docking Study by Bukhari, Syed Nasir Abbas, Abdelgawad, Mohamed Abdelwahab, Ahmed, Naveed, Amjad, Muhammad Wahab, Hussain, Muhammad Ajaz, Elsherif, Mervat A, Ejaz, Hasan, Alotaibi, Nasser H, Filipović, Ignjat, Janković, Nenad

“…In the presented study, eight novel Meldrum's acid derivatives containing various vanillic groups were synthesized. Vanillidene Meldrum's acid compounds were…”
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Synthesis of Thiol-Modified Hemicellulose, Its Biocompatibility, Studies, and Appraisal as a Sustained Release Carrier of Ticagrelor by Zaman, Muhammad, Bajwa, Rabia Imtiaz, Qureshi, Omer Salman, Rehman, Atta Ur, Saeed, Sadaf, Amjad, Muhammad Wahab, Ghafoor Raja, Maria Abdul, Hussain, Muhammad Ajaz

“…Nature has always been considered as the primary source of pharmaceutical ingredients. A variety of hemicelluloses, as well as their modified forms, have been…”
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Editorial: Medicinal chemistry of active pharmaceutical ingredients of drug products by Imran, Mohd, Alhadidi, Qasim M, Khan, Shah Alam, Khamees Thabet, Hamdy, Alam, Ozair, Shakeel, Faiyaz, Rahman, Ziyaur, Amjad, Muhammad Wahab

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Suppression of PGE2 production via disruption of MAPK phosphorylation by unsymmetrical dicarbonyl curcumin derivatives by Mohd Aluwi, Mohd Fadhlizil Fasihi, Rullah, Kamal, Haque, Md. Areeful, Yamin, Bohari M., Ahmad, Waqas, Amjad, Muhammad Wahab, Leong, Sze Wei, Fahmizar, Nurul Amira, Jalil, Juriyati, Abas, Faridah, Ismail, Nor Hadiani, Jantan, Ibrahim, Lam, Kok Wai

“…Curcumin is an important molecule found in turmeric plants and has been reported to exhibit some profound anti-inflammatory activities by interacting with…”
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Ultrasound Targeted Microbubble Cavitation (UTMC) for the treatment of Myocardial Microvascular Obstruction (MVO) by Amjad, Muhammad Wahab, Mohammed, Soheb Anwar, Chen, Xucai, Villanueva, Flordeliza S., Pacella, John J.

“…Congestive heart failure following acute myocardial infarction is increasing due to microvascular obstruction (MVO), for which there is no effective therapy…”
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Abstract 14673: The Effect of Increasing the Ultrasound Pulse Length on Sonoreperfusion Therapy by Yu, Francois T.H., Amjad, Muhammad Wahab, Mohammed, Soheb Anwar, Yu, Gary, Chen, Xucai, Pacella, John

“…BackgroundIn recent years, long and short pulse ultrasound (US)-targeted microbubble cavitation (UTMC) has been shown to increase perfusion in healthy and…”
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Abstract 15543: Fibrin-Targeted Phase Shift Microbubbles Outperform Fibrin-Targeted Microbubbles for the Treatment of Microvascular Obstruction by Mohammed, Soheb Anwar, Amjad, Muhammad Wahab, Chen, Xucai X, Acosta, Maria Fernanda, Hanrahan, Dillon, Unger, Evan, MEUILLET, Emmanuelle, Pacella, John

“…IntroductionMortality from AMI has decreased in recent years; however, microvascular obstruction (MVO) occurs frequently, and is associated with rising…”
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Cardioprotective efficacy of ultrasound-targeted nitrofatty acid microbubbles in rat myocardial ischemia-reperfusion injury model by Amjad, Muhammad Wahab, Mohammed, Soheb Anwar, Fazzari, Marco, Chen, Xucai, Freeman, Bruce, Matsunaga, Terry, Pacella, John J.

“…Over 1 million Americans suffer from acute myocardial infarction (AMI) annually. Although mortality from AMI has decreased, post-AMI congestive heart failure…”
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Fabrication and Characterization of Matrix-Type Transdermal Patches Loaded with Ramipril and Repaglinide Through Cellulose-based Hydrophilic and Hydrophobic Polymers: In Vitro and Ex Vivo Permeation Studies by Zaman, Muhammad, Khalid, Usman, Abdul Ghafoor Raja, Maria, Siddique, Waqar, Sultana, Kishwar, Amjad, Muhammad Wahab, Ur Rehman, Atta, Ahmad Khan, Mahtab

“…Transdermal patches loaded with ramipril and repaglinide were prepared with the ambition to develop matrix-type transdermal drug delivery system for enhanced…”
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Synthesis of α,β-Unsaturated Carbonyl-Based Compounds, Oxime and Oxime Ether Analogs as Potential Anticancer Agents for Overcoming Cancer Multidrug Resistance by Modulation of Efflux Pumps in Tumor Cells by Qin, Hua-Li, Leng, Jing, Zhang, Cheng-Pan, Jantan, Ibrahim, Amjad, Muhammad Wahab, Sher, Muhammad, Naeem-ul-Hassan, Muhammad, Hussain, Muhammad Ajaz, Bukhari, Syed Nasir Abbas

“…Sixty-nine novel α,β-unsaturated carbonyl based compounds, including cyclohexanone, tetralone, oxime, and oxime ether analogs, were synthesized. The…”
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Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and proinflammatory cytokines by Bukhari, Syed Nasir Abbas, Lauro, Gianluigi, Jantan, Ibrahim, Bifulco, Giuseppe, Amjad, Muhammad Wahab

“…Arachidonic acid and its metabolites have generated high level of interest among researchers due to their vital role in inflammation. The inhibition of enzymes…”
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