Search Results - "Amin, Nisar A."

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  1. 1

    A Quantitative Analysis of Subclonal and Clonal Gene Mutations before and after Therapy in Chronic Lymphocytic Leukemia by Amin, Nisar A, Seymour, Erlene, Saiya-Cork, Kamlai, Parkin, Brian, Shedden, Kerby, Malek, Sami N

    Published in Clinical cancer research (01-09-2016)
    “…Chronic lymphocytic leukemia (CLL)-associated gene mutations that influence CLL cell fitness and chemotherapy resistance should increase in clonal…”
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    Journal Article
  2. 2

    Activating STAT6 mutations in follicular lymphoma by Yildiz, Mehmet, Li, Hongxiu, Bernard, Denzil, Amin, Nisar A., Ouillette, Peter, Jones, Siân, Saiya-Cork, Kamlai, Parkin, Brian, Jacobi, Kathryn, Shedden, Kerby, Wang, Shaomeng, Chang, Alfred E., Kaminski, Mark S., Malek, Sami N.

    Published in Blood (22-01-2015)
    “…Follicular lymphoma (FL) is the second most common non-Hodgkin lymphoma in the Western world. FL cell-intrinsic and cell-extrinsic factors influence FL biology…”
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    Journal Article
  3. 3

    Neurokinin B Stimulates GnRH Release in the Male Monkey (Macaca mulatta) and Is Colocalized with Kisspeptin in the Arcuate Nucleus by Ramaswamy, Suresh, Seminara, Stephanie B, Ali, Barkat, Ciofi, Philippe, Amin, Nisar A, Plant, Tony M

    Published in Endocrinology (Philadelphia) (01-09-2010)
    “…Human genetics indicate that kisspeptin and neurokinin B (NKB) signaling are necessary for generating pulsatile LH release and therefore for initiation of…”
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    Journal Article
  4. 4

    Cell-Intrinsic Determinants of Ibrutinib-Induced Apoptosis in Chronic Lymphocytic Leukemia by Amin, Nisar A, Balasubramanian, Sriram, Saiya-Cork, Kamlai, Shedden, Kerby, Hu, Nan, Malek, Sami N

    Published in Clinical cancer research (15-02-2017)
    “…Ibrutinib, a Bruton tyrosine kinase (BTK) inhibitor, is approved for the treatment of relapsed chronic lymphocytic leukemia (CLL) and CLL with del17p…”
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    Journal Article
  5. 5

    Gene Mutations in Chronic Lymphocytic Leukemia by Amin, Nisar A, Malek, Sami N

    Published in Seminars in oncology (01-04-2016)
    “…The recent discovery of genes mutated in CLL has stimulated new research into the role of these genes in CLL pathogenesis. CLL cases carry approximately 5-20…”
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    Journal Article
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    TP53 Mutations and Other Cell-Intrinsic Determinants of the Apoptotic Response to Ibrutinib in Chronic Lymphocytic Leukemia by Amin, Nisar A., Balasubramanian, Sriram, Saiya-Cork, Kamlai, Malek, Sami N.

    Published in Blood (03-12-2015)
    “…Introduction: Ibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, is approved for the treatment of relapsed CLL and CLL with del17p (all lines). Overall…”
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    Journal Article
  8. 8

    A Quantitative Analysis of Subclonal and Clonal Gene Mutations Occurring Pre- and Post-Therapy in 53 Cases of Chronic Lymphocytic Leukemia by Amin, Nisar A., Seymour, Erlene Kuizon, Ulintz, Peter, Saiya-Cork, Kamlai, Parkin, Brian, Shedden, Kerby, Malek, Sami N.

    Published in Blood (03-12-2015)
    “…Introduction: The landscape of gene mutations in CLL prior to therapy is well-characterized. Comparatively less is known about gene mutations and their…”
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    Journal Article
  9. 9

    Analysis of 54 Follicular Lymphomas By Whole Exome Sequencing Identifies Multiple Novel Recurrently Mutated Pathways by Malek, Sami N., Bernard, Denzil, Ying, Zhang Xiao, Peterson, Luke F., Amin, Nisar A., Wang, Shaomeng, Saiya-Cork, Kamlai, Kaminski, Mark S., Chang, Alfred

    Published in Blood (03-12-2015)
    “…Introduction: Follicular lymphoma (FL) constitutes the second most common non-Hodgkin's lymphoma in the Western world. FL carries multiple recurrently mutated…”
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    Journal Article
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