Search Results - "Amigorena, S."

ANTIGEN PRESENTATION AND T CELL STIMULATION BY DENDRITIC CELLS by Guermonprez, Pierre, Valladeau, Jenny, Zitvogel, Laurence, Théry, Clotilde, Amigorena, Sebastian

“…Dendritic cells take up antigens in peripheral tissues, process them into proteolytic peptides, and load these peptides onto major histocompatibility complex…”
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Fc gamma receptors and cross-presentation in dendritic cells by Amigorena, Sebastian

“…M. Bevan showed in the mid-seventies that cytotoxic T lymphocyte (CTL) responses may be initiated by antigen-presenting cells that do not express the antigens…”
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The cell biology of antigen presentation in dendritic cells by Théry, Clotilde, Amigorena, Sebastian

“…Dendritic cells are the most efficient antigen-presenting cells. They take up antigens and pathogens, generate MHC–peptide complexes, migrate from the sites of…”
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Induction of Tolerance by Exosomes and Short‐Term Immunosuppression in a Fully MHC‐Mismatched Rat Cardiac Allograft Model by Pêche, H., Renaudin, K., Beriou, G., Merieau, E., Amigorena, S., Cuturi, M. C.

“…Exosomes are MHC‐bearing vesicles secreted by a wide array of cells. We have previously shown that donor‐haplotype exosomes from bone marrow dendritic cells…”
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Proteomic Analysis of Dendritic Cell-Derived Exosomes: A Secreted Subcellular Compartment Distinct from Apoptotic Vesicles by Thery, Clotilde, Boussac, Muriel, Veron, Philippe, Ricciardi-Castagnoli, Paola, Raposo, Graca, Garin, Jerome, Amigorena, Sebastian

“…Dendritic cells constitutively secrete a population of small (50-90 nm diameter) Ag-presenting vesicles called exosomes. When sensitized with tumor antigenic…”
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Lactadherin promotes VEGF-dependent neovascularization by Mallat, Ziad, Silvestre, Jean-Sébastien, Théry, Clotilde, Hamard, Ghislaine, Boddaert, Jacques, Aguilar, Barbara, Delcayre, Alain, Houbron, Christophe, Tamarat, Radia, Blanc-Brude, Olivier, Heeneman, Sylvia, Clergue, Michel, Duriez, Micheline, Merval, Régine, Lévy, Bernard, Tedgui, Alain, Amigorena, Sebastian

“…Vascular endothelial growth factor (VEGF)-induced blood vessel growth is involved in both physiological and pathological angiogenesis and requires…”
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Milk fat globule-epidermal growth factor-factor VIII (MFGE8) lactadherin promotes bladder tumor development by Sugano, G, Bernard-Pierrot, I, Laé, M, Battail, C, Allory, Y, Stransky, N, Krumeich, S, Lepage, M-L, Maille, P, Donnadieu, M-H, Abbou, C C, Benhamou, S, Lebret, T, Sastre-Garau, X, Amigorena, S, Radvanyi, F, Théry, C

“…Milk fat globule—epidermal growth factor—factor VIII (MFGE8), also called lactadherin or SED1, is a secreted integrin-binding protein that promotes elimination…”
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Tumor-derived exosomes: a new source of tumor rejection antigens by André, F, Schartz, N.E.C, Chaput, N, Flament, C, Raposo, G, Amigorena, S, Angevin, E, Zitvogel, L

“…Exosomes are small vesicles released by a broad array of hematopoietic cells. Previous studies showed that exosomes released by antigen loaded dendritic cells…”
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1810 Neoadjuvant chemotherapy modifies the immune status of tumor-draining lymph nodes of breast cancer patients: Implications for immunotherapy by Nunez, N, Loirat, D, De La Rochere, P, Nadan, A.T, Sastre-Garau, X, Meseure, D, Diéras, V, Milder, M, Viel, S, Sedlik, C, Amigorena, S, Piaggio, P

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Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate by Gerber, P. Pereyra, Cabrini, M., Jancic, C., Paoletti, L., Banchio, C., von Bilderling, C., Sigaut, L., Pietrasanta, L., Duette, G., Freed, E, de Saint Basile, G., Moita, C. Ferreira, Moita, L. Ferreira, Amigorena, S., Benaroch, P., Geffner, J., Ostrowski, Matias

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FcγRI (CD64) Contributes Substantially to Severity of Arthritis, Hypersensitivity Responses, and Protection from Bacterial Infection by Ioan-Facsinay, A, de Kimpe, S.J, Hellwig, S.M.M, van Lent, P.L, Hofhuis, F.M.A, van Ojik, H.H, Sedlik, C, da Silveira, S.A, Gerber, J, de Jong, Y.F, Roozendaal, R, Aarden, L.A, van den Berg, W.B, Saito, T, Mosser, D, Amigorena, S, Izui, S, van Ommen, G-J.B, van Vugt, M, van de Winkel, J.G.J, Verbeek, J.S

“…The high-affinity receptor for IgG, FcγRI, shares its capacity to bind IgG2a immune complexes (IgG2a-IC) with the low-affinity receptor FcγRIII and complement…”
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Autologous Dendritic Cells Prolong Allograft Survival Through Tmem176b‐Dependent Antigen Cross‐Presentation by Segovia, M., Louvet, C., Charnet, P., Savina, A., Tilly, G., Gautreau, L., Carretero‐Iglesia, L., Beriou, G., Cebrian, I., Cens, T., Hepburn, L., Chiffoleau, E., Floto, R. A., Anegon, I., Amigorena, S., Hill, M., Cuturi, M. C.

“…The administration of autologous (recipient‐derived) tolerogenic dendritic cells (ATDCs) is under clinical evaluation. However, the molecular mechanisms by…”
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The B Subunit of Shiga Toxin Fused to a Tumor Antigen Elicits CTL and Targets Dendritic Cells to Allow MHC Class I-Restricted Presentation of Peptides Derived from Exogenous Antigens by Haicheur, Nacilla, Bismuth, Emmanuelle, Bosset, Sophie, Adotevi, Olivier, Warnier, Guy, Lacabanne, Valerie, Regnault, Armelle, Desaymard, Catherine, Amigorena, Sebastian, Ricciardi-Castagnoli, Paola, Goud, Bruno, Fridman, Wolf H, Johannes, Ludger, Tartour, Eric

“…Immunization with peptide or recombinant proteins generally fails to elicit CTL, which are thought to play a key role in the control of virus-infected cells…”
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Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles by Amigorena, S, Webster, P, Drake, J, Newcomb, J, Cresswell, P, Mellman, I

“…B lymphocytes contain a novel population of endocytic vesicles involved in the transport of newly synthesized major histocompatibility complex (MHC) class II…”
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Role of B-cell and Fc receptors in the selection of T-cell epitopes by Amigorena, Sebastian, Bonnerot, Christian

“…The role of specific receptors in antigen internalization and presentation to helper T lymphocytes has been known for more than ten years. However, recent work…”
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P07-08. Spermatozoa capture HIV-1 through heparan sulfate and efficiently transmit the virus to dendritic cells by Lenicov, F Remes, Sabatte, J, Rodrigues, C Rodriguez, Cabrini, M, Jancic, C, Raiden, S, Donalson, M, Pasqualini, R, Marin-Briggiler, C, Vasquez-Levin, M, Capani, F, Amigorena, S, Geffner, J, Ceballos, A

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OA011-03. Clusterin, a natural ligand of DC-SIGN present in human semen inhibits HIV capture and transmission by dendritic cells by Sabatte, J, Faigle, W, Ceballos, A, Morelle, W, Rodríguez, C, Lenicov, F Remes, Thépaut, M, Fieschi, F, Lortat-Jacob, H, Michalski, J, Arenzana-Seisdedos, F, Geffner, J, Amigorena, S

“…In transmission experiments DC were cultured with HIV-1 BaL (5 ng p24Ag) in the presence of clusterin (20 μg/ml), washed and cultured with activated…”
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Vimentin filaments in fibroblasts are a reservoir for SNAP23, a component of the membrane fusion machinery by Faigle, W, Colucci-Guyon, E, Louvard, D, Amigorena, S, Galli, T

“…Soluble N-ethyl maleimide-sensitive fusion protein attachment protein receptors (SNAREs) are core machinery for membrane fusion during intracellular vesicular…”
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Dendritic cell-derived exosomes for cancer therapy by Pitt, Jonathan M, André, Fabrice, Amigorena, Sebastian, Soria, Jean-Charles, Eggermont, Alexander, Kroemer, Guido, Zitvogel, Laurence

“…DC-derived exosomes (Dex) are nanometer-sized membrane vesicles that are secreted by the sentinel antigen-presenting cells of the immune system: DCs. Like DCs,…”
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The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules by ELLIOTT, E. A, DRAKE, J. R, AMIGORENA, S, ELSEMORE, J, WEBSTER, P, MELLMAN, I, FLAVELL, R. A

“…The major histocompatibility complex (MHC) class II-associated invariant chain (Ii) is thought to act as a chaperone that assists class II during folding,…”
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