Search Results - "Amici, Manila"

Protein oxidation and cellular homeostasis: Emphasis on metabolism by Cecarini, Valentina, Gee, Jillian, Fioretti, Evandro, Amici, Manila, Angeletti, Mauro, Eleuteri, Anna Maria, Keller, Jeffrey N.

“…Reactive oxygen species (ROS) are generated as the result of a number of physiological and pathological processes. Once formed ROS can promote multiple forms…”
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Interplay between 20S proteasomes and prion proteins in scrapie disease by Amici, Manila, Cecarini, Valentina, Cuccioloni, Massimiliano, Angeletti, Mauro, Barocci, Simone, Rossi, Giacomo, Fioretti, Evandro, Keller, Jeffrey N., Maria Eleuteri, Anna

“…Scrapie is a transmissible spongiform encephalopathy affecting the central nervous system in sheep. The key event in such neurodegeneration is the conversion…”
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Natural polyphenols as proteasome modulators and their role as anti-cancer compounds by Bonfili, Laura, Cecarini, Valentina, Amici, Manila, Cuccioloni, Massimiliano, Angeletti, Mauro, Keller, Jeffrey N, Eleuteri, Anna M

“…The purpose of this review is to discuss the effect of natural antioxidant compounds as modulators of the 20S proteasome, a multi-enzymatic multi-catalytic…”
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Wheat sprout extract-induced apoptosis in human cancer cells by proteasomes modulation by Bonfili, Laura, Amici, Manila, Cecarini, Valentina, Cuccioloni, Massimiliano, Tacconi, Rosalia, Angeletti, Mauro, Fioretti, Evandro, Keller, Jeffrey N., Eleuteri, Anna Maria

“…Natural occurring modulators of proteasome functionality are extensively investigated for their implication in cancer therapy. On the basis of our previous…”
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Amyloid peptides in different assembly states and related effects on isolated and cellular proteasomes by Cecarini, Valentina, Bonfili, Laura, Amici, Manila, Angeletti, Mauro, Keller, Jeffrey N, Eleuteri, Anna Maria

“…Abstract The role of amyloid-β protein (Aβ) in the pathogenesis of Alzheimer's disease (AD) has been widely investigated and amyloid aggregates are considered…”
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Effect of polyphenolic compounds on the proteolytic activities of constitutive and immuno-proteasomes by Pettinari, Assuntina, Amici, Manila, Cuccioloni, Massimiliano, Angeletti, Mauro, Fioretti, Evandro, Eleuteri, Anna Maria

“…The effect of several polyphenols on the 20S proteasomes, both the constitutive and the LMP proteasomes, isolated from bovine tissues, has been investigated…”
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Peroxynitrite-induced oxidation and its effects on isolated proteasomal systems by Amici, Manila, Lupidi, Giulio, Angeletti, Mauro, Fioretti, Evandro, Eleuteri, Anna Maria

“…The proteasomes are the major intracellular proteolytic systems involved in the removal of altered proteins. In this study, we examined different…”
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Binding of aflatoxins to the 20S proteasome: effects on enzyme functionality and implications for oxidative stress and apoptosis by Amici, Manila, Cecarini, Valentina, Pettinari, Assuntina, Bonfili, Laura, Angeletti, Mauro, Barocci, Simone, Biagetti, Massimo, Fioretti, Evandro, Eleuteri, Anna Maria

“…Aflatoxins (AF) are contaminants of improperly stored foods; they are potent genotoxic and carcinogenic compounds, exerting their effects through damage to…”
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Co-chaperonin GroES as a modulator of proteasomal activity by Cuccioloni, Massimiliano, Montecchia, Francesca, Amici, Manila, Mozzicafreddo, Matteo, Eleuteri, Anna Maria, Angeletti, Mauro

“…The proteasome has a crucial part in the degradation of normal, damaged, mutant or misfolded proteins within both the ubiquitin ATP‐dependent and the ubiquitin…”
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Binding of recombinant PrP c to human plasminogen: Kinetic and thermodynamic study using a resonant mirror biosensor by Cuccioloni, Massimiliano, Amici, Manila, Eleuteri, Anna Maria, Biagetti, Massimo, Barocci, Simone, Angeletti, Mauro

“…Transmissible spongiform encephalopathies are a class of sporadic, genetic and transmissible neurodegenerative diseases that affect both humans and animals…”
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Binding of recombinant PrPc to human plasminogen: Kinetic and thermodynamic study using a resonant mirror biosensor by Cuccioloni, Massimiliano, Amici, Manila, Eleuteri, Anna Maria, Biagetti, Massimo, Barocci, Simone, Angeletti, Mauro

“…Transmissible spongiform encephalopathies are a class of sporadic, genetic and transmissible neurodegenerative diseases that affect both humans and animals…”
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Binding of recombinant PrP super(c) to human plasminogen: Kinetic and thermodynamic study using a resonant mirror biosensor by Cuccioloni, Massimiliano, Amici, Manila, Eleuteri, Anna Maria, Biagetti, Massimo, Barocci, Simone, Angeletti, Mauro

“…Transmissible spongiform encephalopathies are a class of sporadic, genetic and transmissible neurodegenerative diseases that affect both humans and animals…”
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20S proteasome mediated degradation of DHFR: implications in neurodegenerative disorders by Amici, Manila, Sagratini, Danila, Pettinari, Assuntina, Pucciarelli, Stefania, Angeletti, Mauro, Eleuteri, Anna Maria

“…The 20S proteasome is responsible for the degradation of protein substrates implicated in the onset and progression of neurodegenerative disorders, such as…”
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Kinetic and equilibrium characterization of the interaction between bovine trypsin and I-ovalbumin by Cuccioloni, Massimiliano, Sparapani, Luca, Amici, Manila, Lupidi, Giulio, Eleuteri, Anna Maria, Angeletti, Mauro

“…Serpins are a superfamily of structurally linked proteins with interesting functional properties. Most serpins act as proteinase suicide inhibitors and play a…”
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