Search Results - "Ametani, Akio"
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1
Comprehensive single-cell transcriptome analysis reveals heterogeneity in endometrioid adenocarcinoma tissues
Published in Scientific reports (27-10-2017)“…Single cell transcriptome analysis of a cancer tissue can provide objective assessment of subtype population or the activation of each of various…”
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2
Lactobacillus casei inhibits antigen-induced IgE secretion through regulation of cytokine production in murine splenocyte cultures
Published in International archives of allergy and immunology (01-04-1998)“…Lactobacillus casei is a nonpathogenic gram-positive bacterium widely used in dairy products and has been shown to enhance the cellular immunity of the host…”
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3
High-resolution analysis of the 5'-end transcriptome using a next generation DNA sequencer
Published in PloS one (2009)“…Massively parallel, tag-based sequencing systems, such as the SOLiD system, hold the promise of revolutionizing the study of whole genome gene expression due…”
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4
Cytokine responses of human intestinal epithelial-like Caco-2 cells to the nonpathogenic bacterium Bacillus subtilis ( natto)
Published in International journal of food microbiology (15-05-2003)“…Intestinal epithelial cells produce cytokines in response to pathogenic bacteria. However, cellular responses of these cells to nonpathogenic strains, such as…”
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5
Molecular mimics can induce a nonautoaggressive repertoire that preempts induction of autoimmunity
Published in Proceedings of the National Academy of Sciences - PNAS (09-02-2010)“…To determine the role that competition plays in a molecular mimic's capacity to induce autoimmunity, we studied the ability of naïve encephalitogenic T cells…”
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6
Improved growth and viability of lactobacilli in the presence of Bacillus subtilis (natto), catalase, or subtilisin
Published in Canadian journal of microbiology (01-10-2000)“…In an effort to demonstrate the potential usefulness of Bacillus subtilis (natto) as a probiotic, we examined the effect of this organism on the growth of…”
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7
Autoreactive T Cells Can Be Protected from Tolerance Induction through Competition by Flanking Determinants for Access to Class II MHC
Published in Proceedings of the National Academy of Sciences - PNAS (29-04-2003)“…It is not clear why the N-terminal autoantigenic determinant of myelin basic protein (MBP), Ac1-9, is dominant in the B10.PL (H-2u) mouse, given its weak…”
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8
Vaccination with an immunodominant peptide of bovine type II collagen induces an anti‐TCR response, and modulates the onset and severity of collagen‐induced arthritis
Published in International immunology (01-05-2004)“…T cell responses directed toward TCR‐derived peptides have been shown to be an important regulatory mechanism of protection against autoimmunity. Here, we show…”
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9
Macrophage Stimulation Activity of the Polysaccharide Fraction from a Marine Alga (Porphyra yezoensis): Structure-Function Relationships and Improved Solubility
Published in Bioscience, biotechnology, and biochemistry (1995)“…The polysaccharide fraction from Porphyra yezoensis (PASF) has already been shown to stimulate murine phagocytic functions in vivo and in vitro [Yo Yoshizawa…”
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10
Amino Acid Residue Substitution at T-Cell Determinant-flanking Sites in β-Lactoglobulin Modulates Antigen Presentation to T Cells through Subtle Conformational Change
Published in Bioscience, biotechnology, and biochemistry (01-01-2003)“…We compared T-cell responses to regions in residues 21-40 of A and B variants of bovine milk β-lactoglobulin (β-LG) that vary by two different amino acid…”
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11
Antigen presentation by Peyer's patch cells can induce both Th1- and Th2-type responses depending on antigen dosage, but a different cytokine response pattern from that of spleen cells
Published in Bioscience, biotechnology, and biochemistry (01-05-2002)“…The Th1 and Th2 preference induced by cells from the Peyer's patch (PP) and spleen (SPL) with various doses of an antigen was examined. The same splenic T cell…”
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Antigen Feeding Increases Frequency and Antigen-specific Proliferation Ability of Intraepithelial CD4+ T Cells in αβ T Cell Receptor Transgenic Mice
Published in Bioscience, biotechnology, and biochemistry (01-01-2003)“…To study how intestinal intraepithelial lymphocytes (IEL) are affected by orally ingested antigen, the phenotypes and responses of the IEL in mice expressing a…”
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13
Activation of Murine Macrophages by Polysaccharide Fractions from Marine Algae (Porphyra yezoensis)
Published in Bioscience, biotechnology, and biochemistry (1993)“…Two discrete immunomodulating fractions were obtained from marine algae (Porphyra yezoensis): one was the Porphyra water-soluble fraction (PWSF) which was…”
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14
In Vivo Macrophage-stimulation Activity of the Enzyme-degraded Water-soluble Polysaccharide Fraction from a Marine Alga (Gracilaria verrucosa)
Published in Bioscience, biotechnology, and biochemistry (01-10-1996)“…The water-soluble polysaccharide fraction from Gracilaria verrucosa (GWS) has been reported to increase the phagocytic activity of mice [Yoshizawa et al.,…”
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Interleukin 12 and CD86 regulate Th1 and Th2 development induced by a range of antigen doses presented by Peyer's patch and spleen cells
Published in Cytotechnology (Dordrecht) (01-11-2003)“…In this study, we demonstrate the role of interleukin 12 (IL-12), CD80 and CD86 in T helper type 1 (Th1) and Th2 differentiation induced through antigen…”
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Coordinated changes in DNA methylation in antigen-specific memory CD4 T cells
Published in The Journal of immunology (1950) (15-04-2013)“…Memory CD4(+) T cells are central regulators of both humoral and cellular immune responses. T cell differentiation results in specific changes in chromatin…”
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17
Suppression of collagen-induced arthritis in DBA/1J mice by preimmunization with house dust mite extract
Published in Bioscience, biotechnology, and biochemistry (01-05-2001)“…Collagen-induced arthritis (CIA) can be induced in DBA/1J mice by immunization with bovine type 2 collagen (bC2) and is a model of some types of human…”
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18
Screening for the immunopotentiating activity of food microorganisms and enhancement of the immune response by Bifidobacterium adolescentis M101-4
Published in Bioscience, biotechnology, and biochemistry (1993)“…The ability for such lymphocyte activation as growth of the spleen and Peyer's patch (PP) cells from unprimed BALB/c mice, and of lymph node (LN) cells from…”
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19
Fine mapping of T-cell determinants of bovine β-lactoglobin
Published in Cytotechnology (Dordrecht) (01-11-1997)“…T-cell recognition sites, i.e. T-cell determinants, of bovine β-lactoglobulin, a major allergen in milk, were analyzed in detail. For this purpose, we prepared…”
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20
Naïve CD4+ T cells of Peyer's patches produce more IL-6 than those of spleen in response to antigenic stimulation
Published in Immunology letters (30-12-2011)“…Highlights ► Clonotypic CD4+ T cells in Peyer's patches from TCR transgenic mice consist of naïve and memory phenotypic cells. ► Peyer's patch CD4+ T cells…”
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