Search Results - "American journal of translational research"

The antimicrobial peptides and their potential clinical applications by Lei, Jun, Sun, Lichun, Huang, Siyu, Zhu, Chenhong, Li, Ping, He, Jun, Mackey, Vienna, Coy, David H, He, Quanyong

“…Nowadays, the bacterial drug resistance leads to serious healthy problem worldwide due to the long-term use and the abuse of traditional antibiotics result in…”
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Application of virtual reality technology in clinical medicine by Li, Lan, Yu, Fei, Shi, Dongquan, Shi, Jianping, Tian, Zongjun, Yang, Jiquan, Wang, Xingsong, Jiang, Qing

“…The present review discusses the application of virtual reality (VR) technology in clinical medicine, especially in surgical training, pain management and…”
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Lost in translation: animal models and clinical trials in cancer treatment by Mak, Isabella Wy, Evaniew, Nathan, Ghert, Michelle

“…Due to practical and ethical concerns associated with human experimentation, animal models have been essential in cancer research. However, the average rate of…”
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Exosomes from miRNA-126-modified ADSCs promotes functional recovery after stroke in rats by improving neurogenesis and suppressing microglia activation by Geng, Wujun, Tang, Hongli, Luo, Shan, Lv, Ya, Liang, Dongdong, Kang, Xianhui, Hong, Wandong

“…Although adipose derived stem cells (ADSCs) exert their therapeutic potential in ischemic stroke, the migration of ADSCs in injured area is not apparently…”
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Update on the epidemiology, genetics, and therapeutic options of hyperuricemia by Li, Lijun, Zhang, Yipeng, Zeng, Changchun

“…Hyperuricemia may occur when there is an excess of uric acid in the blood. Hyperuricemia may result from increased production or decreased excretion of uric…”
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Metformin induces the M2 macrophage polarization to accelerate the wound healing via regulating AMPK/mTOR/NLRP3 inflammasome singling pathway by Qing, Liming, Fu, Jinfei, Wu, Panfeng, Zhou, Zhengbing, Yu, Fang, Tang, Juyu

“…Skin wound healing is a challenging problem, especially in aging or diabetic patients, which becomes more difficult to heal, and easily results in considerable…”
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The efficacy and safety of remimazolam tosylate versus propofol in patients undergoing colonoscopy: a multicentered, randomized, positive-controlled, phase III clinical trial by Chen, Shaohui, Wang, Jin, Xu, Xiaohan, Huang, Yuguang, Xue, Shanfu, Wu, Anshi, Jin, Xiaoju, Wang, Qiang, Lyu, Jianrui, Wang, Sheng, Li, Yujuan, Yu, Yonghao, Ai, Dengbin, Luo, Ailin, Min, Su, Li, Lin, Zou, Xiaohua, Liu, Jin, Lv, Peilin, Chai, Xiaoqin, Sun, Xude, Zhao, Zhibin, Zhang, Jiaqiang

“…This study aimed to evaluate the efficacy and safety of remimazolam tosylate versus propofol in patients undergoing colonoscopy. In this multicentered,…”
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m6A demethylase FTO promotes hepatocellular carcinoma tumorigenesis via mediating PKM2 demethylation by Li, Jie, Zhu, Lijun, Shi, Yanhong, Liu, Jingnan, Lin, Lin, Chen, Xi

“…N6-methyladenosine (m6A) acts as the most common mRNA modification in mammal cells. Fat Mass and Obesity-associated protein (FTO) is the firstly identified…”
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Mesenchymal stem cell related therapies for cartilage lesions and osteoarthritis by Zhang, Rui, Ma, Jie, Han, Jing, Zhang, Weijie, Ma, Jianbing

“…Osteoarthritis (OA) is a common degenerative joint disease characterized by cartilage degradation, synovitis, subchondral bone sclerosis and osteophyte…”
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Long noncoding RNA GAS5-AS1 suppresses growth and metastasis of cervical cancer by increasing GAS5 stability by Wang, Xiao, Zhang, Junjun, Wang, Yan

“…Cervical cancer (CC) is the second most common cancer and the fourth leading cause of cancer-related death in women worldwide. Up to date, only a few of long…”
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Understanding kidney injury molecule 1: a novel immune factor in kidney pathophysiology by Song, Jiayu, Yu, Jing, Prayogo, Gabriella Wenda, Cao, Weidong, Wu, Yimei, Jia, Zhanjun, Zhang, Aihua

“…Kidney injury molecule 1 (KIM-1) is a type I membrane protein, comprising an extracellular portion and a cytoplasmic portion. It is also named as HAVCR1…”
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Expression patterns and prognostic value of m6A-related genes in colorectal cancer by Liu, Xin, Liu, Liwen, Dong, Zihui, Li, Jianhao, Yu, Yan, Chen, Xiaolong, Ren, Fang, Cui, Guangying, Sun, Ranran

“…Colorectal cancer (CRC), including colon adenocarcinoma (COAD) and rectal adenocarcinoma (READ), is one of the most prevalent malignancies worldwide. N 6…”
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Placenta inflammation is closely associated with gestational diabetes mellitus by Pan, Xue, Jin, Xin, Wang, Jun, Hu, Qing, Dai, Bing

“…OBJECTIVETo investigate the potential role of placenta inflammation in gestational diabetes mellitus (GDM) and construct a model for the diagnosis of GDM…”
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Extensive profiling of circular RNAs and the potential regulatory role of circRNA-000284 in cell proliferation and invasion of cervical cancer via sponging miR-506 by Ma, Han-Bo, Yao, Yi-Nan, Yu, Jin-Jun, Chen, Xue-Xue, Li, Huai-Fang

“…Circular RNAs (circRNAs) are key regulators in the development and progression of human cancers, however its role in cervical cancer tumorigenesis is not well…”
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Macrophages in osteoarthritis: pathophysiology and therapeutics by Chen, Yulin, Jiang, Wei, Yong, Huang, He, Miao, Yang, Yuntao, Deng, Zhenhan, Li, Yusheng

“…Osteoarthritis (OA) is the most common cause of disability in worldwide population, which is characterized by cartilage breakdown, synovial fibrosis,…”
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Circular RNA: a novel biomarker for progressive laryngeal cancer by Xuan, Lijia, Qu, Lingmei, Zhou, Han, Wang, Peng, Yu, Haoyang, Wu, Tianyi, Wang, Xin, Li, Qiuying, Tian, Linli, Liu, Ming, Sun, Yanan

“…Circular RNAs (circRNAs), a class of endogenous RNAs, are characterized by covalently closed continuous loop without 5' to 3' polarity and polyadenylated tail…”
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Role of m5C-related regulatory genes in the diagnosis and prognosis of hepatocellular carcinoma by He, Yuting, Yu, Xiao, Li, Jie, Zhang, Qiyao, Zheng, Qingyuan, Guo, Wenzhi

“…Hepatocellular carcinoma (HCC) is one of the most common malignancies globally, and is frequently associated with a poor prognosis. 5-methylcytosine (m 5 C) is…”
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Understandings of acupuncture application and mechanisms by Lin, Jaung-Geng, Kotha, Peddanna, Chen, Yi-Hung

“…Acupuncture involves the stimulation of acupoints, which are located at specific sites of the human body, by insertion of fine metal needles, followed by…”
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The incidence and survival analysis for anaplastic thyroid cancer: a SEER database analysis by Lin, Bo, Ma, Haiqing, Ma, Maoguang, Zhang, Zhicheng, Sun, Zicheng, Hsieh, I-Yun, Okenwa, Okose, Guan, Haoyan, Li, Jie, Lv, Weiming

“…BACKGROUNDThyroid carcinoma is the most common malignant endocrine tumor; the anaplastic thyroid cancer subtype is aggressive and has a poor prognosis…”
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Role of matrix metalloproteinase in wound healing by Kandhwal, Mimansa, Behl, Tapan, Singh, Sukhbir, Sharma, Neelam, Arora, Sandeep, Bhatia, Saurabh, Al-Harrasi, Ahmed, Sachdeva, Monika, Bungau, Simona

“…Matrix metalloproteinases (MMPs) are a group of endopeptidases that play a vital role in the restoration of damaged skin. Through mediating various cellular…”
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