Search Results - "American journal of physiology. Heart and circulatory physiology"

COVID-19, ACE2, and the cardiovascular consequences by South, Andrew M, Diz, Debra I, Chappell, Mark C

“…The novel SARS coronavirus SARS-CoV-2 pandemic may be particularly deleterious to patients with underlying cardiovascular disease (CVD). The mechanism for…”
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Social isolation during the COVID-19 pandemic can increase physical inactivity and the global burden of cardiovascular disease by Peçanha, Tiago, Goessler, Karla Fabiana, Roschel, Hamilton, Gualano, Bruno

“…Emerging data indicate a substantial decrease in global physical activity levels during the period of social isolation adopted worldwide to contain the spread…”
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Guidelines for experimental models of myocardial ischemia and infarction by Lindsey, Merry L, Bolli, Roberto, Canty, Jr, John M, Du, Xiao-Jun, Frangogiannis, Nikolaos G, Frantz, Stefan, Gourdie, Robert G, Holmes, Jeffrey W, Jones, Steven P, Kloner, Robert A, Lefer, David J, Liao, Ronglih, Murphy, Elizabeth, Ping, Peipei, Przyklenk, Karin, Recchia, Fabio A, Schwartz Longacre, Lisa, Ripplinger, Crystal M, Van Eyk, Jennifer E, Heusch, Gerd

“…Myocardial infarction is a prevalent major cardiovascular event that arises from myocardial ischemia with or without reperfusion, and basic and translational…”
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The renin-angiotensin system: going beyond the classical paradigms by Santos, Robson Augusto Souza, Oudit, Gavin Y, Verano-Braga, Thiago, Canta, Giovanni, Steckelings, Ulrike Muscha, Bader, Michael

“…Thirty years ago, a novel axis of the renin-angiotensin system (RAS) was unveiled by the discovery of angiotensin-(1-7) [ANG-(1-7)] generation in vivo. Later,…”
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Inflammasome, pyroptosis, and cytokines in myocardial ischemia-reperfusion injury by Toldo, Stefano, Mauro, Adolfo G, Cutter, Zachary, Abbate, Antonio

“…Myocardial ischemia-reperfusion injury induces a sterile inflammatory response, leading to further injury that contributes to the final infarct size. Locally…”
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Sex differences in endothelial function important to vascular health and overall cardiovascular disease risk across the lifespan by Stanhewicz, Anna E, Wenner, Megan M, Stachenfeld, Nina S

“…Diseases of the cardiovascular system are the leading cause of morbidity and mortality in men and women in developed countries, and cardiovascular disease…”
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Protective effects of the mechanistic target of rapamycin against excess iron and ferroptosis in cardiomyocytes by Baba, Yuichi, Higa, Jason K, Shimada, Briana K, Horiuchi, Kate M, Suhara, Tomohiro, Kobayashi, Motoi, Woo, Jonathan D, Aoyagi, Hiroko, Marh, Karra S, Kitaoka, Hiroaki, Matsui, Takashi

“…Clinical studies have suggested that myocardial iron is a risk factor for left ventricular remodeling in patients after myocardial infarction. Ferroptosis has…”
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Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging by Toth, Peter, Tarantini, Stefano, Csiszar, Anna, Ungvari, Zoltan

“…Increasing evidence from epidemiological, clinical and experimental studies indicate that age-related cerebromicrovascular dysfunction and microcirculatory…”
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Elastin, arterial mechanics, and cardiovascular disease by Cocciolone, Austin J, Hawes, Jie Z, Staiculescu, Marius C, Johnson, Elizabeth O, Murshed, Monzur, Wagenseil, Jessica E

“…Large, elastic arteries are composed of cells and a specialized extracellular matrix that provides reversible elasticity and strength. Elastin is the matrix…”
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Guidelines for measuring cardiac physiology in mice by Lindsey, Merry L, Kassiri, Zamaneh, Virag, Jitka A I, de Castro Brás, Lisandra E, Scherrer-Crosbie, Marielle

“…Cardiovascular disease is a leading cause of death, and translational research is needed to understand better mechanisms whereby the left ventricle responds to…”
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Sex differences in COVID-19: candidate pathways, genetics of ACE2, and sex hormones by Viveiros, Anissa, Rasmuson, Jaslyn, Vu, Jennie, Mulvagh, Sharon L, Yip, Cindy Y Y, Norris, Colleen M, Oudit, Gavin Y

“…Biological sex is increasingly recognized as a critical determinant of health and disease, particularly relevant to the topical COVID-19 pandemic caused by the…”
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Guidelines for evaluating myocardial cell death by Mishra, Paras K, Adameova, Adriana, Hill, Joseph A, Baines, Christopher P, Kang, Peter M, Downey, James M, Narula, Jagat, Takahashi, Masafumi, Abbate, Antonio, Piristine, Hande C, Kar, Sumit, Su, Shi, Higa, Jason K, Kawasaki, Nicholas K, Matsui, Takashi

“…Cell death is a fundamental process in cardiac pathologies. Recent studies have revealed multiple forms of cell death, and several of them have been…”
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Drug-induced mitochondrial dysfunction and cardiotoxicity by Varga, Zoltán V, Ferdinandy, Peter, Liaudet, Lucas, Pacher, Pál

“…Mitochondria has an essential role in myocardial tissue homeostasis; thus deterioration in mitochondrial function eventually leads to cardiomyocyte and…”
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Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells by Sampilvanjil, Ariunaa, Karasawa, Tadayoshi, Yamada, Naoya, Komada, Takanori, Higashi, Tsunehito, Baatarjav, Chintogtokh, Watanabe, Sachiko, Kamata, Ryo, Ohno, Nobuhiko, Takahashi, Masafumi

“…Cigarette smoking is a major risk factor for aortic aneurysm and dissection; however, no causative link between smoking and these aortic disorders has been…”
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Tobacco smoking induces cardiovascular mitochondrial oxidative stress, promotes endothelial dysfunction, and enhances hypertension by Dikalov, Sergey, Itani, Hana, Richmond, Bradley, Vergeade, Aurelia, Rahman, S M Jamshedur, Boutaud, Olivier, Blackwell, Timothy, Massion, Pierre P, Harrison, David G, Dikalova, Anna

“…Tobacco smoking is a major risk factor for cardiovascular disease and hypertension. It is associated with the oxidative stress and induces metabolic…”
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The role of sirtuins in cardiac disease by Matsushima, Shouji, Sadoshima, Junichi

“…Modification of histones is one of the important mechanisms of epigenetics, in which genetic control is determined by factors other than an individual's DNA…”
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Embryonic stem cell-derived exosomes inhibit doxorubicin-induced TLR4-NLRP3-mediated cell death-pyroptosis by Tavakoli Dargani, Zahra, Singla, Dinender K

“…Doxorubicin (Dox)-induced cardiac side effects are regulated through increased oxidative stress and apoptosis. However, it remains unknown whether Dox induces…”
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Tricuspid annular plane systolic excursion and pulmonary arterial systolic pressure relationship in heart failure: an index of right ventricular contractile function and prognosis by Guazzi, M, Bandera, F, Pelissero, G, Castelvecchio, S, Menicanti, L, Ghio, S, Temporelli, P L, Arena, R

“…Echo-derived pulmonary arterial systolic pressure (PASP) and right ventricular (RV) tricuspid annular plane systolic excursion (TAPSE; from the end of diastole…”
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LncRNA TUG1 mediates ischemic myocardial injury by targeting miR-132-3p/HDAC3 axis by Su, Qiang, Liu, Yang, Lv, Xiang-Wei, Dai, Ri-Xin, Yang, Xi-Heng, Kong, Bing-Hui

“…Increased production of reactive oxygen species (ROS) significantly contributed to the pathogenesis of acute myocardial infarction (AMI). Recent studies…”
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Oxidative stress and heart failure by Tsutsui, Hiroyuki, Kinugawa, Shintaro, Matsushima, Shouji

“…Oxidative stress, defined as an excess production of reactive oxygen species (ROS) relative to antioxidant defense, has been shown to play an important role in…”
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