Search Results - "Amelia C. Crampin"

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study by Kaforou, Myrsini, Wright, Victoria J, Oni, Tolu, French, Neil, Anderson, Suzanne T, Bangani, Nonzwakazi, Banwell, Claire M, Brent, Andrew J, Crampin, Amelia C, Dockrell, Hazel M, Eley, Brian, Heyderman, Robert S, Hibberd, Martin L, Kern, Florian, Langford, Paul R, Ling, Ling, Mendelson, Marc, Ottenhoff, Tom H, Zgambo, Femia, Wilkinson, Robert J, Coin, Lachlan J, Levin, Michael

“…A major impediment to tuberculosis control in Africa is the difficulty in diagnosing active tuberculosis (TB), particularly in the context of HIV infection. We…”
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A blood RNA signature for tuberculosis disease risk: a prospective cohort study by Zak, Daniel E, PhD, Penn-Nicholson, Adam, PhD, Scriba, Thomas J, PhD, Thompson, Ethan, PhD, Suliman, Sara, PhD, Amon, Lynn M, PhD, Mahomed, Hassan, MD, Erasmus, Mzwandile, BSc, Whatney, Wendy, BScHons, Hussey, Gregory D, Prof, Abrahams, Deborah, DipMT, Kafaar, Fazlin, DipNur, Hawkridge, Tony, FCPHM, Verver, Suzanne, PhD, Hughes, E Jane, BScHons, Ota, Martin, MD, Sutherland, Jayne, PhD, Howe, Rawleigh, MD, Dockrell, Hazel M, Prof, Boom, W Henry, Prof, Thiel, Bonnie, MS, Ottenhoff, Tom H M, Prof, Mayanja-Kizza, Harriet, Prof, Crampin, Amelia C, FFPHM, Downing, Katrina, PhD, Hatherill, Mark, MD, Valvo, Joe, BS, Shankar, Smitha, MS, Parida, Shreemanta K, MD, Kaufmann, Stefan H E, Prof, Walzl, Gerhard, Prof, Aderem, Alan, PhD, Hanekom, Willem A, Prof

“…Summary Background Identification of blood biomarkers that prospectively predict progression of Mycobacterium tuberculosis infection to tuberculosis disease…”
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Probabilistic Cause-of-Death Assignment Using Verbal Autopsies by McCormick, Tyler H., Li, Zehang Richard, Calvert, Clara, Crampin, Amelia C., Kahn, Kathleen, Clark, Samuel J.

“…In regions without complete-coverage civil registration and vital statistics systems there is uncertainty about even the most basic demographic indicators. In…”
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Prevalence of obesity, hypertension, and diabetes, and cascade of care in sub-Saharan Africa: a cross-sectional, population-based study in rural and urban Malawi by Price, Alison J, Crampin, Amelia C, Amberbir, Alemayehu, Kayuni-Chihana, Ndoliwe, Musicha, Crispin, Tafatatha, Terence, Branson, Keith, Lawlor, Debbie A, Mwaiyeghele, Elenaus, Nkhwazi, Lawrence, Smeeth, Liam, Pearce, Neil, Munthali, Elizabeth, Mwagomba, Beatrice M, Mwansambo, Charles, Glynn, Judith R, Jaffar, Shabbar, Nyirenda, Moffat

“…Sub-Saharan Africa is in rapid demographic transition, and non-communicable diseases are increasingly important causes of morbidity and mortality. We…”
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Diagnosis of Childhood Tuberculosis and Host RNA Expression in Africa by Anderson, Suzanne T, Kaforou, Myrsini, Brent, Andrew J, Wright, Victoria J, Banwell, Claire M, Chagaluka, George, Crampin, Amelia C, Dockrell, Hazel M, French, Neil, Hamilton, Melissa S, Hibberd, Martin L, Kern, Florian, Langford, Paul R, Ling, Ling, Mlotha, Rachel, Ottenhoff, Tom H.M, Pienaar, Sandy, Pillay, Vashini, Scott, J. Anthony G, Twahir, Hemed, Wilkinson, Robert J, Coin, Lachlan J, Heyderman, Robert S, Levin, Michael, Eley, Brian

“…Diagnosing active tuberculosis remains a challenge, especially in children. In this study, which included HIV-negative and HIV-positive children, a…”
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Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi by Glynn, Judith R, Guerra-Assunção, José Afonso, Houben, Rein M G J, Sichali, Lifted, Mzembe, Themba, Mwaungulu, Lorrain K, Mwaungulu, J Nimrod, McNerney, Ruth, Khan, Palwasha, Parkhill, Julian, Crampin, Amelia C, Clark, Taane G

“…The proportion of tuberculosis attributable to transmission from close contacts is not well known. Comparison of the genome of strains from index patients and…”
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Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data by Sobkowiak, Benjamin, Glynn, Judith R, Houben, Rein M G J, Mallard, Kim, Phelan, Jody E, Guerra-Assunção, José Afonso, Banda, Louis, Mzembe, Themba, Viveiros, Miguel, McNerney, Ruth, Parkhill, Julian, Crampin, Amelia C, Clark, Taane G

“…Mixed, polyclonal Mycobacterium tuberculosis infection occurs in natural populations. Developing an effective method for detecting such cases is important in…”
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Early school failure predicts teenage pregnancy and marriage: A large population-based cohort study in northern Malawi by Glynn, Judith R, Sunny, Bindu S, DeStavola, Bianca, Dube, Albert, Chihana, Menard, Price, Alison J, Crampin, Amelia C

“…School dropout has been linked to early pregnancy and marriage but less is known about the effect of school performance. We aimed to assess whether school…”
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Effect of Acute Illness on Contact Patterns, Malawi, 2017 by Glynn, Judith R, McLean, Estelle, Malava, Jullita, Dube, Albert, Katundu, Cynthia, Crampin, Amelia C, Geis, Steffen

“…The way persons interact when ill could profoundly affect transmission of infectious agents. To obtain data on these patterns in Africa, we recorded…”
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Contribution of remote M.tuberculosis infection to tuberculosis disease: A 30-year population study by Glynn, Judith R, Khan, Palwasha, Mzembe, Themba, Sichali, Lifted, Fine, Paul E M, Crampin, Amelia C, Houben, Rein M G J

“…The importance of remote infection with M.tuberculosis as a cause of tuberculosis disease (TB) is unclear, with limited evidence of impact on TB rates beyond…”
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Effects of exclusive breastfeeding on educational attainment and longitudinal trajectories of grade progression among children in a 13-year follow-up study in Malawi by Mohammed, Shamsudeen, Webb, Emily L., Calvert, Clara, Glynn, Judith R., Sunny, Bindu S., Crampin, Amelia C., McLean, Estelle, Munthali-Mkandawire, Shekinah, Lazarous Nkhata Dube, Albert, Kalobekamo, Fredrick, Marston, Milly, Oakley, Laura L.

“…The benefits of exclusive breastfeeding (EBF) for infant health and survival are well documented. However, its impact on educational outcomes has been…”
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Qualitative study of practices and attitudes towards physical activity among prediabetic men and women in urban and rural Malawi by Banda, Jethro, Bunn, Christopher, Crampin, Amelia C, Gill, Jason M R, Gray, Cindy M

“…ObjectivesGiven the decline in physical activity levels in Malawi, like other sub-Saharan African countries, and its implication for non-communicable disease…”
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Multi-country collaborative citizen science projects to co-design cardiovascular disease prevention strategies and advocacy: findings from Ethiopia, Malawi, Rwanda, and South Africa by Okop, Kufre J, Kedir, Kiya, Kasenda, Stephen, Niyibizi, Jean Berchmans, Chipeta, Effie, Getachew, Hailemichael, Sell, Kerstin, Lambert, Estelle Victoria, Puoane, Thandi, Rulisa, Stephen, Bunn, Christopher, King, Abby C, Bavuma, Charlotte, Howe, Rawleigh, Crampin, Amelia C, Levitt, Naomi S

“…Cardiovascular diseases (CVD) were responsible for 20.5 million annual deaths globally in 2021, with a disproportionally high burden in sub-Saharan Africa…”
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Identification of Reduced Host Transcriptomic Signatures for Tuberculosis Disease and Digital PCR-Based Validation and Quantification by Gliddon, Harriet D, Kaforou, Myrsini, Alikian, Mary, Habgood-Coote, Dominic, Zhou, Chenxi, Oni, Tolu, Anderson, Suzanne T, Brent, Andrew J, Crampin, Amelia C, Eley, Brian, Heyderman, Robert, Kern, Florian, Langford, Paul R, Ottenhoff, Tom H M, Hibberd, Martin L, French, Neil, Wright, Victoria J, Dockrell, Hazel M, Coin, Lachlan J, Wilkinson, Robert J, Levin, Michael

“…Recently, host whole blood gene expression signatures have been identified for diagnosis of tuberculosis (TB). Absolute quantification of the concentrations of…”
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Does early linear growth failure influence later school performance? A cohort study in Karonga district, northern Malawi by Sunny, Bindu S, DeStavola, Bianca, Dube, Albert, Kondowe, Scotch, Crampin, Amelia C, Glynn, Judith R

“…Stunting or linear growth retardation in childhood is associated with delayed cognitive development due to related causes (malnutrition, illness, poor…”
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Correction: Prevalence and risk factors for chronic kidney disease of unknown cause in Malawi: a cross-sectional analysis in a rural and urban population by Hamilton, Sophie A, Nakanga, Wisdom P, Prynn, Josephine E, Crampin, Amelia C, Fecht, Daniela, Vineis, Paolo, Caplin, Ben, Pearce, Neil, Nyirenda, Moffat J

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An integrated whole genome analysis of Mycobacterium tuberculosis reveals insights into relationship between its genome, transcriptome and methylome by Gomez-Gonzalez, Paula J., Andreu, Nuria, Phelan, Jody E., de Sessions, Paola Florez, Glynn, Judith R., Crampin, Amelia C., Campino, Susana, Butcher, Philip D., Hibberd, Martin L., Clark, Taane G.

“…Human tuberculosis disease (TB), caused by Mycobacterium tuberculosis ( Mtb) , is a complex disease, with a spectrum of outcomes. Genomic, transcriptomic and…”
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Evaluation of Host Serum Protein Biomarkers of Tuberculosis in sub-Saharan Africa by Morris, Thomas C, Hoggart, Clive J, Chegou, Novel N, Kidd, Martin, Oni, Tolu, Goliath, Rene, Wilkinson, Katalin A, Dockrell, Hazel M, Sichali, Lifted, Banda, Louis, Crampin, Amelia C, French, Neil, Walzl, Gerhard, Levin, Michael, Wilkinson, Robert J, Hamilton, Melissa S

“…Accurate and affordable point-of-care diagnostics for tuberculosis (TB) are needed. Host serum protein signatures have been derived for use in primary care…”
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A comparison of the associations between adiposity and lipids in Malawi and the United Kingdom by Soares, Ana Luiza G, Banda, Louis, Amberbir, Alemayehu, Jaffar, Shabbar, Musicha, Crispin, Price, Alison J, Crampin, Amelia C, Nyirenda, Moffat J, Lawlor, Deborah A

“…The prevalence of excess adiposity, as measured by elevated body mass index (BMI) and waist-hip ratio (WHR), is increasing in sub-Saharan African (SSA)…”
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Population-level effect of HIV on adult mortality and early evidence of reversal after introduction of antiretroviral therapy in Malawi by Jahn, Andreas, Dr, Floyd, Sian, MSc, Crampin, Amelia C, MBChB, Mwaungulu, Frank, MD, Mvula, Hazzie, Munthali, Fipson, McGrath, Nuala, PhD, Mwafilaso, Johnbosco, Mwinuka, Venance, Mangongo, Bernard, Fine, Paul EM, Prof, Zaba, Basia, MSc, Glynn, Judith R, Prof

“…Summary Background Malawi, which has about 80 000 deaths from AIDS every year, made free antiretroviral therapy available to more than 80 000 patients between…”
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