Search Results - "Ameenuddin, Syed"
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Insulin Therapy is Associated With Increased Myocardial Interstitial Fibrosis and Cardiomyocyte Apoptosis in a Rodent Model of Experimental Diabetes
Published in Frontiers in physiology (27-04-2022)“…The incidence of diabetes mellitus (DM) is rising. DM is a risk factor for developing left ventricular (LV) dysfunction and adverse cardiovascular outcomes…”
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Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury
Published in Journal of neurochemistry (01-06-2006)“…Minocycline, a clinically used tetracycline for over 40 years, crosses the blood–brain barrier and prevents caspase up‐regulation. It reduces apoptosis in…”
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Spectrotemporal resolution tradeoff in auditory processing as revealed by human auditory brainstem responses and psychophysical indices
Published in Neuroscience letters (20-06-2014)“…•Spectrotemporal tradeoffs assessed via auditory brainstem and behavioral responses.•Neural temporal resolution (∼4ms) was inversely related to spectral…”
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Synthesis, Material Properties, and Biocompatibility of a Novel Self-Cross-Linkable Poly(caprolactone fumarate) as an Injectable Tissue Engineering Scaffold
Published in Biomacromolecules (01-09-2005)“…A novel self-cross-linkable and biodegradable macromer, poly(caprolactone fumarate) (PCLF), has been developed for guided bone regeneration. This macromer is a…”
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Participation of protease‐activated receptor‐1 in thrombin‐induced microglial activation
Published in Journal of neurochemistry (01-02-2002)“…Activation of microglia, the resident macrophages in the CNS, plays a significant role in neuronal death or degeneration in a broad spectrum of CNS disorders…”
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The Effect of the Brain-Type Natriuretic Peptide Single-Nucleotide Polymorphism rs198389 on Test Characteristics of Common Assays
Published in Mayo Clinic proceedings (01-03-2011)“…OBJECTIVE To assess in a US general adult population the effect of the functional single-nucleotide polymorphism rs198389 in the promoter region of the gene of…”
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CARDIAC APOPTOSIS IS INCREASED IN A RODENT MODEL OF EARLY NON-ALCOHOLIC FATTY LIVER DISEASE
Published in Journal of the American College of Cardiology (02-04-2024)Get full text
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Abstract 9778: The Biological Effects of a Novel Bispecific Designer Peptide (CRRL 094) in a Rat Model of Experimental Diabetes
Published in Circulation (New York, N.Y.) (08-11-2022)“…IntroductionThe prevalence of diabetes mellitus (DM) is increasing, and it is associated with cardiorenal dysfunction. Natriuretic peptides (NPs) have…”
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The Glucose-lowering And Cardiorenal Effects Of CRRL094, A Novel Bispecific Peptide, Versus Exogenous Insulin In Experimental Diabetes
Published in Journal of cardiac failure (01-01-2024)“…Diabetes mellitus (DM) continues to increase in prevalence, along with its deleterious cardiorenal effects. Exogenous insulin, a mainstay of DM therapy, may…”
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INSULIN THERAPY IN A RAT MODEL OF DIABETIC CARDIOMYOPATHY IS ASSOCIATED WITH ATTENUATION OF THE CGMP SYSTEM
Published in Journal of the American College of Cardiology (12-03-2019)Get full text
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Membrane lipid peroxidation in neurodegeneration: Role of thrombin and proteinase-activated receptor-1
Published in Brain research (15-07-2016)“…Abstract Thrombin and membrane lipid peroxidation (MLP) have been implicated in various central nervous system (CNS) disorders from CNS trauma to stroke,…”
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107 - Experimental Model of Type 2 Diabetic Cardiomyopathy: A State of cGMP Deficiency
Published in Journal of cardiac failure (01-08-2016)Get full text
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Experimental Model of Type 2 Diabetic Cardiomyopathy: A State of cGMP Deficiency
Published in Journal of cardiac failure (01-08-2016)Get full text
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In vivo biodegradation and biocompatibility of PEG/sebacic acid-based hydrogels using a cage implant system
Published in Journal of biomedical materials research. Part A (01-10-2010)“…Comprehensive in vivo biodegradability and biocompatibility of unmodified and Arg‐Gly‐Asp (RGD) peptide‐modified PEG/sebacic acid‐based hydrogels were…”
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Multiple-channel scaffolds to promote spinal cord axon regeneration
Published in Biomaterials (2006)“…As molecular, cellular, and tissue-level treatments for spinal cord injury are discovered, it is likely that combinations of such treatments will be necessary…”
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Co-operative Highway Lane Merge Control of Autonomous Self-driving Ground Vehicles
Published 01-01-2018“…ADAS (Advanced Driver Assist System), promises to reduce automotive accident deaths, improving road safety as well as enhance the driving experience, where the…”
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Dissertation