Search Results - "Ame, Shaali"
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Diagnosis of soil-transmitted helminths using the Kato-Katz technique: What is the influence of stirring, storage time and storage temperature on stool sample egg counts?
Published in PLoS neglected tropical diseases (22-01-2021)“…Soil-transmitted helminths infect about one fifth of the world's population and have a negative impact on health. The Kato-Katz technique is the recommended…”
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Sensitivity and Specificity of a Urine Circulating Anodic Antigen Test for the Diagnosis of Schistosoma haematobium in Low Endemic Settings
Published in PLoS neglected tropical diseases (01-05-2015)“…Elimination of schistosomiasis as a public health problem and interruption of transmission in selected areas are key goals of the World Health Organization for…”
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Long-term outcomes of ivermectin-albendazole versus albendazole alone against soil-transmitted helminths: Results from randomized controlled trials in Lao PDR and Pemba Island, Tanzania
Published in PLoS neglected tropical diseases (01-06-2021)“…Preventive chemotherapy is the cornerstone of soil-transmitted helminth (STH) control. Long-term outcomes and adequate treatment frequency of the recently…”
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A 5-Year intervention study on elimination of urogenital schistosomiasis in Zanzibar: Parasitological results of annual cross-sectional surveys
Published in PLoS neglected tropical diseases (01-05-2019)“…The Zanzibar Elimination of Schistosomiasis Transmission (ZEST) project aimed to eliminate urogenital schistosomiasis as a public health problem from Pemba and…”
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Efficacy and safety of co-administered ivermectin and albendazole in school-aged children and adults infected with Trichuris trichiura in Côte d'Ivoire, Laos, and Pemba Island, Tanzania: a double-blind, parallel-group, phase 3, randomised controlled trial
Published in The Lancet infectious diseases (01-01-2022)“…Preventive chemotherapy with albendazole or mebendazole remains one of the cornerstones of soil-transmitted helminth control. However, these drugs are less…”
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Quality control in the diagnosis of Trichuris trichiura and Ascaris lumbricoides using the Kato-Katz technique: experience from three randomised controlled trials
Published in Parasites & vectors (05-02-2015)“…An accurate diagnosis of soil-transmitted helminthiasis is important for individual patient management, for drug efficacy evaluation and for monitoring control…”
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Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against Trichuris trichiura and concomitant soil-transmitted helminth infections: a four-arm, randomised controlled trial
Published in The Lancet infectious diseases (01-03-2015)“…Summary Background Existing anthelmintic drugs (eg, albendazole and mebendazole) have low efficacy against the intestinal nematode species Trichuris trichiura…”
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Diagnostic comparison between FECPAKG2 and the Kato-Katz method for analyzing soil-transmitted helminth eggs in stool
Published in PLoS neglected tropical diseases (01-06-2018)“…Over one billion people are infected with soil-transmitted helminths (STH), i.e. Ascaris lumbricoides, hookworm and Trichuris trichiura. For estimating drug…”
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RNA profiles reveal signatures of future health and disease in pregnancy
Published in Nature (London) (20-01-2022)“…Maternal morbidity and mortality continue to rise, and pre-eclampsia is a major driver of this burden 1 . Yet the ability to assess underlying pathophysiology…”
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A general framework to support cost-efficient fecal egg count methods and study design choices for large-scale STH deworming programs-monitoring of therapeutic drug efficacy as a case study
Published in PLoS neglected tropical diseases (01-05-2023)“…Soil-transmitted helminth (STH) control programs currently lack evidence-based recommendations for cost-efficient survey designs for monitoring and evaluation…”
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Assessment of anthelmintic efficacy of mebendazole in school children in six countries where soil-transmitted helminths are endemic
Published in PLoS neglected tropical diseases (01-10-2014)“…Robust reference values for fecal egg count reduction (FECR) rates of the most widely used anthelmintic drugs in preventive chemotherapy (PC) programs for…”
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Efficacy and tolerability of moxidectin alone and in co-administration with albendazole and tribendimidine versus albendazole plus oxantel pamoate against Trichuris trichiura infections: a randomised, non-inferiority, single-blind trial
Published in The Lancet infectious diseases (01-08-2018)“…The recommended anthelmintics show low efficacy in a single-dose regimen against Trichuris trichiura. Moxidectin, a new treatment for river blindness, might…”
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Efficacy and Safety of Ascending Dosages of Moxidectin and Moxidectin-albendazole Against Trichuris trichiura in Adolescents: A Randomized Controlled Trial
Published in Clinical infectious diseases (03-03-2020)“…Abstract Background Preventive chemotherapy is the main strategy to control soil-transmitted helminth (STH) infections. Albendazole and mebendazole are…”
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Evaluation of two communication tools, slideshow and theater, to improve participants' understanding of a clinical trial in the informed consent procedure on Pemba Island, Tanzania
Published in PLoS neglected tropical diseases (14-05-2021)“…Clinical trial participants are required to sign an informed consent form (ICF). However, information is lacking on the most effective methods to convey trial…”
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Development of a recombinase polymerase amplification (RPA) fluorescence assay for the detection of Schistosoma haematobium
Published in Parasites & vectors (04-11-2019)“…Accurate diagnosis of urogenital schistosomiasis is vital for surveillance and control programmes. While a number of diagnostic techniques are available there…”
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Analytical and Clinical Assessment of a Portable, Isothermal Recombinase Polymerase Amplification (RPA) Assay for the Molecular Diagnosis of Urogenital Schistosomiasis
Published in Molecules (Basel, Switzerland) (11-09-2020)“…Accurate diagnosis of urogenital schistosomiasis is crucial for disease surveillance and control. Routine diagnostic methods, however, lack sensitivity when…”
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Urogenital schistosomiasis elimination in Zanzibar: accuracy of urine filtration and haematuria reagent strips for diagnosing light intensity Schistosoma haematobium infections
Published in Parasites & vectors (23-10-2018)“…Urine filtration and microhaematuria reagent strips are basic standard diagnostic methods to detect urogenital schistosomiasis. We assessed their accuracy for…”
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Individual responses to a single oral dose of albendazole indicate reduced efficacy against soil-transmitted helminths in an area with high drug pressure
Published in PLoS neglected tropical diseases (01-10-2021)“…Albendazole (ALB) is administered annually to millions of children through global deworming programs targeting soil-transmitted helminths (STHs: Ascaris…”
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Ancient Hybridization and Adaptive Introgression of an Invadolysin Gene in Schistosome Parasites
Published in Molecular biology and evolution (01-10-2019)“…Abstract Introgression among parasite species has the potential to transfer traits of biomedical importance across species boundaries. The parasitic blood…”
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Study and implementation of urogenital schistosomiasis elimination in Zanzibar (Unguja and Pemba islands) using an integrated multidisciplinary approach
Published in BMC public health (30-10-2012)“…Schistosomiasis is a parasitic infection that continues to be a major public health problem in many developing countries being responsible for an estimated…”
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