Search Results - "Ambrose, Helen"

Experiencing success: an occupational therapy partnership programme. Gymnastics for children with attention deficit hyperactivity disorder by Ambrose, Helen

“…Purpose>This paper aims to outline and evaluate a pilot partnership programme – an Occupational Therapy–led gymnastics group intervention for children aged…”
Get full text

Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study by Granerod, Julia, MSc, Ambrose, Helen E, DPhil, Davies, Nicholas WS, PhD, Clewley, Jonathan P, PhD, Walsh, Amanda L, MSc, Morgan, Dilys, MD, Cunningham, Richard, FRCPath, Zuckerman, Mark, FRCPath, Mutton, Ken J, MBBS, Solomon, Tom, Prof, Ward, Katherine N, PhD, Lunn, Michael PT, FRCP, Irani, Sarosh R, MRCP, Vincent, Angela, Prof, Brown, David WG, Prof, Crowcroft, Natasha S, MD

“…Summary Background Encephalitis has many causes, but for most patients the cause is unknown. We aimed to establish the cause and identify the clinical…”
Get full text

Rosuvastatin pharmacokinetics and pharmacogenetics in Caucasian and Asian subjects residing in the United States by Birmingham, Bruce K., Bujac, Sarah R., Elsby, Robert, Azumaya, Connie T., Zalikowski, Julie, Chen, Yusong, Kim, Kenneth, Ambrose, Helen J.

“…Purpose Systemic exposure to rosuvastatin in Asian subjects living in Japan or Singapore is approximately twice that observed in Caucasian subjects in Western…”
Get full text

Impact of ABCG2 and SLCO1B1 polymorphisms on pharmacokinetics of rosuvastatin, atorvastatin and simvastatin acid in Caucasian and Asian subjects: a class effect? by Birmingham, Bruce K., Bujac, Sarah R., Elsby, Robert, Azumaya, Connie T., Wei, Cheryl, Chen, Yusong, Mosqueda-Garcia, Rogelio, Ambrose, Helen J.

“…Purpose Systemic exposure to rosuvastatin is approximately double that of Caucasians in Asian subjects. We investigated whether this pattern of increased…”
Get full text

Effect of ADRB2 polymorphisms on response to longacting β2 -agonist therapy: a pharmacogenetic analysis of two randomised studies by Bleecker, Eugene R, Prof, Postma, Dirkje S, Prof, Lawrance, Rachael M, BSc, Meyers, Deborah A, Prof, Ambrose, Helen J, PhD, Goldman, Mitch, MD

“…Summary Background New evidence has suggested that people with asthma who are homozygous for arginine at aminoacid 16 of the β2 -adrenergic receptor (ADRB2)…”
Get full text

Accurate detection of low prevalence AKT1 E17K mutation in tissue or plasma from advanced cancer patients by de Bruin, Elza C, Whiteley, Jessica L, Corcoran, Claire, Kirk, Pauline M, Fox, Jayne C, Armisen, Javier, Lindemann, Justin P O, Schiavon, Gaia, Ambrose, Helen J, Kohlmann, Alexander

“…Personalized healthcare relies on accurate companion diagnostic assays that enable the most appropriate treatment decision for cancer patients. Extensive assay…”
Get full text

Biomarker-directed targeted therapy plus durvalumab in advanced non-small-cell lung cancer: a phase 2 umbrella trial by Besse, Benjamin, Pons-Tostivint, Elvire, Park, Keunchil, Hartl, Sylvia, Forde, Patrick M., Hochmair, Maximilian J., Awad, Mark M., Thomas, Michael, Goss, Glenwood, Wheatley-Price, Paul, Shepherd, Frances A., Florescu, Marie, Cheema, Parneet, Chu, Quincy S. C., Kim, Sang-We, Morgensztern, Daniel, Johnson, Melissa L., Cousin, Sophie, Kim, Dong-Wan, Moskovitz, Mor T., Vicente, David, Aronson, Boaz, Hobson, Rosalind, Ambrose, Helen J., Khosla, Sajan, Reddy, Avinash, Russell, Deanna L., Keddar, Mohamed Reda, Conway, James P., Barrett, J. Carl, Dean, Emma, Kumar, Rakesh, Dressman, Marlene, Jewsbury, Philip J., Iyer, Sonia, Barry, Simon T., Cosaert, Jan, Heymach, John V.

“…For patients with non-small-cell lung cancer (NSCLC) tumors without currently targetable molecular alterations, standard-of-care treatment is immunotherapy…”
Get full text

Development and Validation of Confirmatory Foot-and-Mouth Disease Virus Antibody ELISAs to Identify Infected Animals in Vaccinated Populations by Tewari, Anuj, Ambrose, Helen, Parekh, Krupali, Inoue, Toru, Guitian, Javier, Nardo, Antonello Di, Paton, David James, Parida, Satya

“…In foot-and-mouth disease (FMD)-endemic countries, vaccination is commonly used to control the disease, whilst in FMD-free countries, vaccination is considered…”
Get full text

Capivasertib, an AKT Kinase Inhibitor, as Monotherapy or in Combination with Fulvestrant in Patients with AKT1 E17K -Mutant, ER-Positive Metastatic Breast Cancer by Smyth, Lillian M, Tamura, Kenji, Oliveira, Mafalda, Ciruelos, Eva M, Mayer, Ingrid A, Sablin, Marie-Paule, Biganzoli, Laura, Ambrose, Helen J, Ashton, Jack, Barnicle, Alan, Cashell, Des D, Corcoran, Claire, de Bruin, Elza C, Foxley, Andrew, Hauser, Joana, Lindemann, Justin P O, Maudsley, Rhiannon, McEwen, Robert, Moschetta, Michele, Pass, Martin, Rowlands, Vicky, Schiavon, Gaia, Banerji, Udai, Scaltriti, Maurizio, Taylor, Barry S, Chandarlapaty, Sarat, Baselga, José, Hyman, David M

“…The activating mutation occurs in approximately 7% of estrogen receptor-positive (ER ) metastatic breast cancer (MBC). We report, from a multipart,…”
Get full text

Effect of β2-adrenergic receptor gene (ADRB2) 3' untranslated region polymorphisms on inhaled corticosteroid/long-acting β2-adrenergic agonist response by Ambrose, Helen J, Lawrance, Rachael M, Cresswell, Carl J, Goldman, Mitchell, Meyers, Deborah A, Bleecker, Eugene R

“…Evidence suggests that variation in the length of the poly-C repeat in the 3' untranslated region (3'UTR) of the β2-adrenergic receptor gene (ADRB2) may…”
Get full text

Prevalence of disease related prion protein in anonymous tonsil specimens in Britain: cross sectional opportunistic survey by Clewley, Jonathan P, Kelly, Carole M, Andrews, Nick, Vogliqi, Kelly, Mallinson, Gary, Kaisar, Maria, Hilton, David A, Ironside, James W, Edwards, Philip, McCardle, Linda M, Ritchie, Diane L, Dabaghian, Reza, Ambrose, Helen E, Gill, O Noel

“…Objective To establish with improved accuracy the prevalence of disease related prion protein (PrPCJD) in the population of Britain and thereby guide a…”
Get full text

Virus discovery by sequence-independent genome amplification by Ambrose, Helen E., Clewley, Jonathan P.

“…Genome sequences from several blood borne and respiratory viruses have recently been recovered directly from clinical specimens by variants of a technique…”
Get full text

Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer by Smyth, Lillian M., Batist, Gerald, Meric-Bernstam, Funda, Kabos, Peter, Spanggaard, Iben, Lluch, Ana, Jhaveri, Komal, Varga, Andrea, Wong, Andrea, Schram, Alison M., Ambrose, Helen, Carr, T. Hedley, de Bruin, Elza C., Salinas-Souza, Carolina, Foxley, Andrew, Hauser, Joana, Lindemann, Justin P. O., Maudsley, Rhiannon, McEwen, Robert, Moschetta, Michele, Nikolaou, Myria, Schiavon, Gaia, Razavi, Pedram, Banerji, Udai, Baselga, José, Hyman, David M., Chandarlapaty, Sarat

“…Five to ten percent of ER+ metastatic breast cancer (MBC) tumors harbor somatic PTEN mutations. Loss of function of this tumor-suppressor gene defines a highly…”
Get full text

Limited Asymptomatic Carriage of Pneumocystis jiroveci in Human Immunodeficiency Virus–Infected Patients by Wakefield, Ann E, Lindley, Austin R, Ambrose, Helen E, Denis, Cecile-Marie, Miller, Robert F

“…Forty-seven bronchoalveolar lavage fluid samples from 16 human immunodeficiency virus (HIV)–infected patients were used to test the latency model of…”
Get full text

Poly(ADP-ribose) polymerase-1 (Parp-1)-deficient mice demonstrate abnormal antibody responses by Ambrose, Helen E, Willimott, Shaun, Beswick, Richard W, Dantzer, Françoise, de Murcia, Josiane Ménissier, Yelamos, José, Wagner, Simon D

“…Poly(ADP-ribosylation) of acceptor proteins is an epigenetic modification involved in DNA strand break repair, recombination and transcription. Here we provide…”
Get full text

Pneumocystis carinii f. sp. hominis DNA in immunocompetent health care workers in contact with patients with P. carinii pneumonia by MILLER, Robert F, AMBROSE, Helen E, WAKEFIELD, Ann E

“…The possible transmission of Pneumocystis carinii f. sp. hominis from patients with P. carinii pneumonia to asymptomatic health care workers (HCW), with or…”
Get full text

Probable Mother-to-Infant Transmission of Pneumocystis carinii f. sp. hominis Infection by MILLER, Robert F, AMBROSE, Helen E, NOVELLI, Vas, WAKEFIELD, Ann E

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Nocodazole, a microtubule depolymerising agent, induces apoptosis of chronic lymphocytic leukaemia cells associated with changes in Bcl-2 phosphorylation and expression by Beswick, Richard W., Ambrose, Helen E., Wagner, Simon D.

“…Microtubule active drugs are used in the treatment of malignancies and their mechanism of action in cycling cells is to produce mitotic arrest followed by…”
Get full text

Genotypes of Pneumocystis jiroveci Isolates Obtained in Harare, Zimbabwe, and London, United Kingdom by MILLER, Robert F, LINDLEY, Austin R, AMBROSE, Helen E, MALIN, Adam S, WAKEFIELD, Ann E

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

SNPs and pharmacogenomics by Ambrose, Helen J

Get more information