Search Results - "Ambroggio, Ernesto E."
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Differential Interaction of Antimicrobial Peptides with Lipid Structures Studied by Coarse-Grained Molecular Dynamics Simulations
Published in Molecules (Basel, Switzerland) (20-10-2017)“…In this work; we investigated the differential interaction of amphiphilic antimicrobial peptides with 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC)…”
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Direct Visualization of Membrane Leakage Induced by the Antibiotic Peptides: Maculatin, Citropin, and Aurein
Published in Biophysical journal (01-09-2005)“…Membrane lysis caused by antibiotic peptides is often rationalized by means of two different models: the so-called carpet model and the pore-forming model. We…”
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Arf1 and membrane curvature cooperate to recruit Arfaptin2 to liposomes
Published in PloS one (29-04-2013)“…Arfaptin2 contains a Bin/Amphiphysin/Rvs (BAR) domain and directly interacts with proteins of the Arf/Arl family in their active GTP-bound state. It has been…”
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Dengue and Zika virus capsid proteins bind to membranes and self-assemble into liquid droplets with nucleic acids
Published in The Journal of biological chemistry (01-09-2021)“…Dengue virus (DENV) and Zika virus (ZIKV) capsid proteins efficiently recruit and surround the viral RNA at the endoplasmic reticulum (ER) membrane to yield…”
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Phosphatidylserine lipids and membrane order precisely regulate the activity of Polybia-MP1 peptide
Published in Biochimica et biophysica acta. Biomembranes (01-06-2017)“…Polybia-MP1 (IDWKKLLDAAKQIL-NH2) is a lytic peptide from the Brazilian wasp venom with known anti-cancer properties. Previous evidence indicates that…”
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Multidimensional Spectral Phasors of LAURDAN’s Excitation–Emission Matrices: The Ultimate Sensor for Lipid Phases?
Published in Journal of the American Chemical Society (26-06-2024)“…The impact of lipid diversity on the lateral organization of biological membranes remains a topic of debate. While the existence of domains in lamellar…”
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The amphiphilic alkyl ester derivatives of l-ascorbic acid induce reorganization of phospholipid vesicles
Published in Biochimica et biophysica acta (01-09-2016)“…l-ascorbic acid alkyl esters (ASCn) are lipophilic forms of vitamin C, which maintain some of its antioxidant power. Those properties make this drug family…”
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The rheological properties of beta amyloid Langmuir monolayers: Comparative studies with melittin peptide
Published in Colloids and surfaces, B, Biointerfaces (01-10-2016)“…Monolayers of β-sheet short peptides exhibit a marked shear which is absent in monolayers of α-helix short peptides that lack of strong intermolecular…”
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Myristoylation and Oligonucleotide Interaction Modulate Peptide and Protein Surface Properties: The Case of the HIV‑1 Matrix Domain
Published in Langmuir (29-05-2018)“…Myristoylated proteins typically develop a tight association with membranes. One example is the matrix domain (MA) of the HIV-1 Gag protein. In addition, MA is…”
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Amyloid oligomerization of the Parkinson's disease related protein α‐synuclein impacts on its curvature‐membrane sensitivity
Published in Journal of neurochemistry (01-11-2018)“…The amyloid aggregation of the presynaptic protein α‐synuclein (AS) is pathognomonic of Parkinson's disease and other neurodegenerative disorders…”
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Membrane Restructuring Events during the Enzymatic Generation of Ceramides with Very Long-Chain Polyunsaturated Fatty Acids
Published in Langmuir (10-04-2018)“…In rat sperm heads, sphingomyelin (SM) species that contain very long-chain polyunsaturated fatty acid (V-SM) become ceramides (V-Cer) after inducing in vitro…”
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Reversing the peptide sequence impacts on molecular surface behaviour
Published in Colloids and surfaces, B, Biointerfaces (01-03-2016)“…[Display omitted] •Peptide sequence reversion confers a distinctive peptide surface behaviuor and rheology.•Langmuir monolayers of peptides with a hydrophilic…”
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Lipid-like behavior of signal sequence peptides at air–water interface
Published in Biochimica et biophysica acta (01-02-2013)“…Several protein transport processes in the cell are mediated by signal sequence peptides located at the N-terminal side of the mature protein sequence. To…”
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Amyloid-β Peptide Disruption of Lipid Membranes and the Effect of Metal Ions
Published in Journal of molecular biology (24-02-2006)“…β-Amyloid peptide (Aβ), which is cleaved from the larger trans-membrane amyloid precursor protein, is found deposited in the brain of patients suffering from…”
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Surface Behavior and Lipid Interaction of Alzheimer β-Amyloid Peptide 1–42: A Membrane-Disrupting Peptide
Published in Biophysical journal (01-04-2005)“…Amyloid aggregates, found in patients that suffer from Alzheimer's disease, are composed of fibril-forming peptides in a β-sheet conformation. One of the most…”
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Dengue and Zika virus capsid proteins bind to membranes and self-assemble into liquid droplets with nucleic acids
Published in The Journal of biological chemistry (01-09-2021)Get full text
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Surface behaviour and peptide–lipid interactions of the antibiotic peptides, Maculatin and Citropin
Published in Biochimica et biophysica acta (01-07-2004)“…Surface behaviour of Maculatin 1.1 and Citropin 1.1 antibiotic peptides have been studied using the Langmuir monolayer technique in order to understand the…”
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Biophysical properties of a synthetic transit peptide from wheat chloroplast ribulose 1,5-bisphosphate carboxylase
Published in Journal of peptide science (01-04-2007)“…The surface properties of pure RuBisCo transit peptide (RTP) and its interaction with zwitterionic, anionic phospholipids and chloroplast lipids were studied…”
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Interfacial properties of the M1 segment of the nicotinic acetylcholine receptor
Published in Biophysical chemistry (01-06-2006)“…We have studied the thermodynamic, surface, and structural properties of αM1 transmembrane sequence of the nicotinic acetylcholine receptor (nAChR) by using…”
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Surface Behavior and Lipid Interaction of Alzheimer [beta]-Amyloid Peptide 1-42: A Membrane-Disrupting Peptide
Published in Biophysical journal (01-04-2005)“…Amyloid aggregates, found in patients that suffer from Alzheimer's disease, are composed of fibril-forming peptides in a β-sheet conformation. One of the most…”
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