Search Results - "Amatya, Rina"
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The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
Published in The Journal of experimental medicine (30-06-2014)“…Linear ubiquitination is a newly discovered posttranslational modification that is currently restricted to a small number of known protein substrates. The…”
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Complete Genome Sequence of Torque teno indri virus 1 , a Novel Anellovirus in Blood from a Free-Living Lemur
Published in Genome announcements (Washington, DC) (27-07-2017)“…We identified (TTIV1), the first anellovirus in a free-living lemur ( ). The complete circular 2,572-nucleotide (nt) TTIV1 genome is distantly related to…”
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Posttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain Formation
Published in mBio (17-11-2015)“…Linear ubiquitination is an atypical posttranslational modification catalyzed by the linear-ubiquitin-chain assembly complex (LUBAC), containing HOIP, HOIL-1L,…”
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Nanoprodrugs of NSAIDs: Preparation and Characterization of Flufenamic Acid Nanoprodrugs
Published in Journal of Drug Delivery (01-01-2011)“…We demonstrated that hydrophobic derivatives of the nonsteroidal anti-inflammatory drug (NSAID)flufenamic acid (FA), can be formed into stable nanometer-sized…”
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Multi-step regulation of innate immune signaling by Kaposi's sarcoma-associated herpesvirus
Published in Virus research (02-11-2015)“…•Activation of innate immune response.•Type I interferon response to control pathogen infection.•Kaposi's sarcoma-associated herpesvirus (KSHV)-mediated immune…”
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Reactive Oxygen Species Responsive Nanoprodrug to Treat Intracranial Glioblastoma
Published in ACS nano (23-04-2013)“…Chemotherapy for intracranial gliomas is hampered by limited delivery of therapeutic agents through the blood brain barrier (BBB). An optimal therapeutic agent…”
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