Search Results - "Amaro, Mariana"

Highly synergistic antimicrobial activity of magainin 2 and PGLa peptides is rooted in the formation of supramolecular complexes with lipids by Aisenbrey, Christopher, Amaro, Mariana, Pospíšil, Petr, Hof, Martin, Bechinger, Burkhard

“…Magainin 2 and PGLa are cationic, amphipathic antimicrobial peptides which when added as equimolar mixture exhibit a pronounced synergism in both their…”
Get full text

Isothermal denaturation fluorimetry vs differential scanning fluorimetry as tools for screening of stabilizers for protein freeze-drying: Human phenylalanine hydroxylase as the case study by Leandro, Paula, Lino, Paulo R., Lopes, Raquel, Leandro, João, Amaro, Mariana P., Sousa, Paulo, Vicente, João B., Almeida, António J.

“…[Display omitted] The structural maintenance of therapeutic proteins during formulation and/or storage is a critical aspect, particularly for multi-domain…”
Get full text

Systematic Modification and Evaluation of Enzyme-Loaded Chitosan Nanoparticles by Lino, Paulo R., Leandro, João, Figueiredo, Lara, Amaro, Mariana P., Gonçalves, Lídia M. D., Leandro, Paula, Almeida, António J.

“…Polymeric-based nano drug delivery systems have been widely exploited to overcome protein instability during formulation. Presently, a diverse range of…”
Get full text

On multivalent receptor activity of GM1 in cholesterol containing membranes by Šachl, Radek, Amaro, Mariana, Aydogan, Gokcan, Koukalová, Alena, Mikhalyov, Ilya I., Boldyrev, Ivan A., Humpolíčková, Jana, Hof, Martin

“…Gangliosides located at the outer leaflet of plasma membrane are molecules that either participate in recognizing of exogenous ligand molecules or exhibit…”
Get full text

Lipid Driven Nanodomains in Giant Lipid Vesicles are Fluid and Disordered by Koukalová, Alena, Amaro, Mariana, Aydogan, Gokcan, Gröbner, Gerhard, Williamson, Philip T. F., Mikhalyov, Ilya, Hof, Martin, Šachl, Radek

“…It is a fundamental question in cell biology and biophysics whether sphingomyelin (SM)- and cholesterol (Chol)- driven nanodomains exist in living cells and in…”
Get full text

What Does Time-Dependent Fluorescence Shift (TDFS) in Biomembranes (and Proteins) Report on? by Scollo, Federica, Evci, Hüseyin, Amaro, Mariana, Jurkiewicz, Piotr, Sykora, Jan, Hof, Martin

“…The organization of biomolecules and bioassemblies is highly governed by the nature and extent of their interactions with water. These interactions are of high…”
Get full text

Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice by Argmann, Carmen A., Violante, Sara, Dodatko, Tetyana, Amaro, Mariana P., Hagen, Jacob, Gillespie, Virginia L., Buettner, Christoph, Schadt, Eric E., Houten, Sander M.

“…The transcription factor Krüppel-like factor 14 (KLF14) has been associated with type 2 diabetes and high-density lipoprotein-cholesterol (HDL-C) through…”
Get full text

Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability by Tomé, Catarina S., Lopes, Raquel R., Sousa, Pedro M. F., Amaro, Mariana P., Leandro, João, Mertens, Haydyn D. T., Leandro, Paula, Vicente, João B.

“…Human phenylalanine hydroxylase (hPAH) hydroxylates l -phenylalanine ( l -Phe) to l -tyrosine, a precursor for neurotransmitter biosynthesis. Phenylketonuria…”
Get full text

New Technologies for Expedited Forest Inventory Using Smartphone Applications by André Sandim, Mariana Amaro, Maria Emilia Silva, Jorge Cunha, Susana Morais, Alexandra Marques, André Ferreira, José Luis Lousada, Teresa Fonseca

“…The forest inventory plays a crucial role in forest management planning, and it is the first step in planning actions for forest production. However,…”
Get full text

Author Correction: Structure of full-length wild-type human phenylalanine hydroxylase by small angle X-ray scattering reveals substrate-induced conformational stability by Tomé, Catarina S., Lopes, Raquel R., Sousa, Pedro M. F., Amaro, Mariana P., Leandro, João, Mertens, Haydyn D. T., Leandro, Paula, Vicente, João B.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties by Ragaller, Franziska, Andronico, Luca, Sykora, Jan, Kulig, Waldemar, Rog, Tomasz, Urem, Yagmur Balim, Abhinav, Danylchuk, Dmytro I, Hof, Martin, Klymchenko, Andrey, Amaro, Mariana, Vattulainen, Ilpo, Sezgin, Erdinc

“…The plasma membrane, as a highly complex cell organelle, serves as a crucial platform for a multitude of cellular processes. Its collective biophysical…”
Get full text

Site-Specific Analysis of Protein Hydration Based on Unnatural Amino Acid Fluorescence by Amaro, Mariana, Brezovský, Jan, Kováčová, Silvia, Sýkora, Jan, Bednář, David, Němec, Václav, Lišková, Veronika, Kurumbang, Nagendra Prasad, Beerens, Koen, Chaloupková, Radka, Paruch, Kamil, Hof, Martin, Damborský, Jiří

“…Hydration of proteins profoundly affects their functions. We describe a simple and general method for site-specific analysis of protein hydration based on the…”
Get full text

A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients by Peters, Lauren A., Friedman, Joshua R., Stojmirovic, Aleksandar, Hagen, Jacob, Houten, Sander, Dodatko, Tetyana, Amaro, Mariana P., Restrepo, Paula, Chai, Zhi, Rodrigo Mora, J., Raymond, Holly A., Curran, Mark, Dobrin, Radu, Das, Anuk, Xiong, Huabao, Schadt, Eric E., Argmann, Carmen, Losic, Bojan

“…Previous studies have conducted time course characterization of murine colitis models through transcriptional profiling of differential expression. We…”
Get full text

In Silico and In Vitro Tailoring of a Chitosan Nanoformulation of a Human Metabolic Enzyme by Lino, Paulo R, Leandro, João, Amaro, Mariana, Gonçalves, Lídia M D, Leandro, Paula, Almeida, António J

“…Enzyme nanoencapsulation holds an enormous potential to develop new therapeutic approaches to a large set of human pathologies including cancer, infectious…”
Get full text

Early detection of amyloid aggregation using intrinsic fluorescence by Rolinski, Olaf J., Amaro, Mariana, Birch, David J.S.

“…Beta-amyloid (Aβ) aggregation, believed to be responsible for Alzheimer's disease, is monitored using its intrinsic fluorescence decay. Alterations in the…”
Get full text

Imagens de mundos de jogo e práticas espaciais by Amaro, Mariana, Fragoso, Suely, Freitas, Fabiana

“…Este artigo aborda o impacto das imagens dos mundos de jogo sobre as práticas espaciais dos jogadores. Inicia lembrando que as imagens não são ingênuas e passa…”
Get full text

Impact of GM1 on Membrane-Mediated Aggregation/Oligomerization of β-Amyloid: Unifying View by Cebecauer, Marek, Hof, Martin, Amaro, Mariana

“…In this perspective we summarize current knowledge of the effect of monosialoganglioside GM1 on the membrane-mediated aggregation of the β-amyloid (Aβ)…”
Get full text

Membrane Lipid Nanodomains by Cebecauer, Marek, Amaro, Mariana, Jurkiewicz, Piotr, Sarmento, Maria João, Šachl, Radek, Cwiklik, Lukasz, Hof, Martin

“…Lipid membranes can spontaneously organize their components into domains of different sizes and properties. The organization of membrane lipids into…”
Get full text

Time-Resolved Fluorescence in Lipid Bilayers: Selected Applications and Advantages over Steady State by Amaro, Mariana, Šachl, Radek, Jurkiewicz, Piotr, Coutinho, Ana, Prieto, Manuel, Hof, Martin

“…Fluorescence methods are versatile tools for obtaining dynamic and topological information about biomembranes because the molecular interactions taking place…”
Get full text

Organization of gangliosides into membrane nanodomains by Sarmento, Maria J., Ricardo, Joana C., Amaro, Mariana, Šachl, Radek

“…Gangliosides are glycosphingolipids consisting of a ceramide base and a bulky sugar chain that contains one or more sialic acids. This unique structure endows…”
Get full text