Search Results - "Amaro, Filipa"

Metabolomics Reveals Tyrosine Kinase Inhibitor Resistance-Associated Metabolic Events in Human Metastatic Renal Cancer Cells by Amaro, Filipa, Carvalho, Márcia, Bastos, Maria de Lourdes, Guedes de Pinho, Paula, Pinto, Joana

“…The development of resistance to tyrosine kinase inhibitors (TKIs) is a major cause of treatment failure in metastatic renal cell carcinoma (mRCC). A deeper…”
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Advances and Perspectives in Prostate Cancer Biomarker Discovery in the Last 5 Years through Tissue and Urine Metabolomics by Lima, Ana Rita, Pinto, Joana, Amaro, Filipa, Bastos, Maria de Lourdes, Carvalho, Márcia, Guedes de Pinho, Paula

“…Prostate cancer (PCa) is the second most diagnosed cancer in men worldwide. For its screening, serum prostate specific antigen (PSA) test has been largely…”
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β-Adrenoceptor Activation in Breast MCF-10A Cells Induces a Pattern of Catecholamine Production Similar to that of Tumorigenic MCF-7 Cells by Amaro, Filipa, Silva, Dany, Reguengo, Henrique, Oliveira, José C, Quintas, Clara, Vale, Nuno, Gonçalves, Jorge, Fresco, Paula

“…Adrenaline, which participates in the neuroendocrine response that occurs during stress and perimenopause, may be tumorigenic. This exploratory study aimed at…”
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Sunitinib versus Pazopanib Dilemma in Renal Cell Carcinoma: New Insights into the In Vitro Metabolic Impact, Efficacy, and Safety by Amaro, Filipa, Pisoeiro, Carolina, Valente, Maria João, Bastos, Maria de Lourdes, Guedes de Pinho, Paula, Carvalho, Márcia, Pinto, Joana

“…Sunitinib and pazopanib are tyrosine kinase inhibitors (TKIs) used as first-line therapy for metastatic renal cell carcinoma (RCC). Although these TKIs are…”
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Pharmacometabolomics Applied to Personalized Medicine in Urological Cancers by Amaro, Filipa, Carvalho, Márcia, Bastos, Maria de Lourdes, Guedes de Pinho, Paula, Pinto, Joana

“…Prostate cancer (PCa), bladder cancer (BCa), and renal cell carcinoma (RCC) are the most common urological cancers, and their incidence has been rising over…”
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Discovery of Volatile Biomarkers for Bladder Cancer Detection and Staging through Urine Metabolomics by Pinto, Joana, Carapito, Ângela, Amaro, Filipa, Lima, Ana Rita, Carvalho-Maia, Carina, Martins, Maria Conceição, Jerónimo, Carmen, Henrique, Rui, Bastos, Maria de Lourdes, Guedes de Pinho, Paula

“…Timely diagnosis is crucial to improve the long-term survival of bladder cancer (BC) patients. The discovery of new BC biomarkers based in urine analysis is…”
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Quercus suber Bark as a Sustainable Source of Value-Added Compounds: Experimental Studies with Cork By-Products by Liliana Rego, Sandra Mota, Ana Torres, Cláudia Pinto, Sara Cravo, Joana Rocha e Silva, Ricardo N. M. J. Páscoa, Agostinho Almeida, Filipa Amaro, Paula Guedes Pinho, Honorina Cidade, José Paulo Silva, José Manuel Sousa Lobo, Isabel Filipa Almeida

“…Quercus suber L. bark (cork) is a sustainable material due to its ability to regenerate. The aim of this work was to explore cork powders, by-products of the…”
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Effect of Rhizobium mechanisms in improving tolerance to saline stress in lettuce plants by Ayuso-Calles, Miguel, Flores-Félix, José David, Amaro, Filipa, García-Estévez, Ignacio, Jiménez-Gómez, Alejandro, de Pinho, Paula Guedes, Escribano-Bailón, M. Teresa, Rivas, Raúl

“…Background Soils affected by salinity are a recurring problem that is continually increasing due to the impact of climate change on weather conditions and…”
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The Impact of Different Closures on the Flavor Composition of Wines during Bottle Aging by Furtado, Isabel, Lopes, Paulo, Oliveira, Ana Sofia, Amaro, Filipa, Bastos, Maria de Lourdes, Cabral, Miguel, Guedes de Pinho, Paula, Pinto, Joana

“…Wine flavor undergoes major changes during bottle aging and can be influenced by the type of closure. The interaction between wine, the type of closure and the…”
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Impact of Cork Closures on the Volatile Profile of Sparkling Wines during Bottle Aging by Amaro, Filipa, Almeida, Joana, Oliveira, Ana Sofia, Furtado, Isabel, Bastos, Maria de Lourdes, Guedes de Pinho, Paula, Pinto, Joana

“…This study aimed at investigating the impact of different technical cork stoppers on the quality preservation and shelf life of sparkling wines. The volatile…”
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Mineral Content and Volatile Profiling of Prunus avium L. (Sweet Cherry) By-Products from Fundão Region (Portugal) by Nunes, Ana R, Gonçalves, Ana C, Pinto, Edgar, Amaro, Filipa, Flores-Félix, José D, Almeida, Agostinho, Guedes de Pinho, Paula, Falcão, Amílcar, Alves, Gilberto, Silva, Luís R

“…Large amounts of L. by-products result from sweet cherry production and processing. This work aimed to evaluate the mineral content and volatile profiling of…”
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MnTnHex-2-PyP5+ Displays Anticancer Properties and Enhances Cisplatin Effects in Non-Small Cell Lung Cancer Cells by Soares, Rita, Manguinhas, Rita, Costa, João, Saraiva, Nuno, Gil, Nuno, Rosell, Rafael, Camões, Sérgio, Batinic-Haberle, Ines, Spasojevic, Ivan, Castro, Matilde, Miranda, Joana, Amaro, Filipa, Pinto, Joana, Fernandes, Ana, Guedes de Pinho, Paula, Oliveira, Nuno

“…The manganese(III) porphyrin MnTnHex-2-PyP5+ (MnTnHex) is a potent superoxide dismutase mimic and modulator of redox-based transcriptional activity that has…”
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Volatilomics Reveals Potential Biomarkers for Identification of Renal Cell Carcinoma: An In Vitro Approach by Amaro, Filipa, Pinto, Joana, Rocha, Sílvia, Araújo, Ana Margarida, Miranda-Gonçalves, Vera, Jerónimo, Carmen, Henrique, Rui, de Lourdes Bastos, Maria, Carvalho, Márcia, de Pinho, Paula Guedes

“…The identification of noninvasive biomarkers able to detect renal cell carcinoma (RCC) at an early stage remains an unmet clinical need. The recognition that…”
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Carbidopa Alters Tryptophan Metabolism in Breast Cancer and Melanoma Cells Leading to the Formation of Indole-3-Acetonitrile, a Pro-Proliferative Metabolite by Duarte, Diana, Amaro, Filipa, Silva, Isabel, Silva, Dany, Fresco, Paula, Oliveira, José C, Reguengo, Henrique, Gonçalves, Jorge, Vale, Nuno

“…Carbidopa is used for the treatment of Parkinson's disease (PD) as an inhibitor of DOPA decarboxylase, and PD patients taking carbidopa have a lower incidence…”
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Development of a new procedure for the determination of the reactivity of brandies used in wine fortification by Azevedo, Joana, Pissarra, João, Amaro, Filipa, Guido, Luis, Oliveira, Joana, Lopes, Paulo, Guedes de Pinho, Paula, Mateus, Nuno, De Freitas, Victor

“…The main purpose of this work was to describe and validate a new methodology for the determination of a brandy reactivity index (BRI) towards flavan-3-ol…”
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Impact of benzo[a]pyrene, phenanthrene, and their mixtures on the matebolome of hepatocytes isolated from fish by Monteiro, Vânia, Bramatti, Isabella, Amaro, Filipa, Guedes de Pinho, Paula, Figueiredo, Neusa, Dias da Silva, Diana, Martins, Marta, Pinto, Joana

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Metabolic signature biomarkers for predicting the recurrence of urological cancers by Amaro, Filipa, Carvalho, Márcia, Bastos, Maria de Lourdes, Guedes de Pinho, Paula, Pinto, Joana

“…[Display omitted] •Urological cancers’ recurrence can be predicted using pre-surgery metabolic signatures.•Best recurrence predictors in prostate cancer…”
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Urinary Volatilomics Unveils a Candidate Biomarker Panel for Noninvasive Detection of Clear Cell Renal Cell Carcinoma by Pinto, Joana, Amaro, Filipa, Lima, Ana Rita, Carvalho-Maia, Carina, Jerónimo, Carmen, Henrique, Rui, Bastos, Maria de Lourdes, Carvalho, Márcia, Guedes de Pinho, Paula

“…Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer usually associated with asymptomatic development and risk of systemic…”
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Impact of the redox-active MnTnHex-2-PyP5+ and cisplatin on the metabolome of non-small cell lung cancer cells by Soares, Rita B., Pinto, Joana, Amaro, Filipa, Manguinhas, Rita, Gil, Nuno, Rosell, Rafael, Batinic-Haberle, Ines, Fernandes, Ana S., Oliveira, Nuno G., Guedes de Pinho, Paula

“…[Display omitted] Redox-based cancer therapeutic strategies aim to raise reactive oxygen species (ROS) levels in cancer cells, thus modifying their redox…”
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Volatile profile of cork as a tool for classification of natural cork stoppers by Furtado, Isabel, Oliveira, Ana Sofia, Amaro, Filipa, Lopes, Paulo, Cabral, Miguel, Bastos, Maria de Lourdes, Guedes de Pinho, Paula, Pinto, Joana

“…An untargeted approach, focused in the profile of volatile organic compounds (VOCs), was applied to differentiate natural cork stoppers with different levels…”
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