Search Results - "Amarasinghe, G K"

NMR structure of the HIV-1 nucleocapsid protein bound to stem-loop SL2 of the psi-RNA packaging signal. Implications for genome recognition by Amarasinghe, G K, De Guzman, R N, Turner, R B, Chancellor, K J, Wu, Z R, Summers, M F

“…The RNA genome of the human immunodeficiency virus type-1 (HIV-1) contains a approximately 120 nucleotide Psi-packaging signal that is recognized by the…”
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Stem-loop SL4 of the HIV-1 Ψ RNA packaging signal exhibits weak affinity for the nucleocapsid protein. structural studies and implications for genome recognition by Amarasinghe, Gaya K., Zhou, Jing, Miskimon, Matthew, Chancellor, Kalola J., McDonald, Jasmine A., Matthews, Akida G., Miller, Robyn R., Rouse, Michael D., Summers, Michael F.

“…Encapsidation of the genome of the human immunodeficiency virus type-1 (HIV-1) during retrovirus assembly is mediated by interactions between the nucleocapsid…”
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NMR structure of stem-loop SL2 of the HIV-1 psi RNA packaging signal reveals a novel A-U-A base-triple platform by Amarasinghe, G K, De Guzman, R N, Turner, R B, Summers, M F

“…The genome of the human immunodeficiency virus type-1 (HIV-1) contains a stretch of approximately 120 nucleotides known as the psi-site that is essential for…”
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A Viral RNA Structural Element Alters Host Recognition of Nonself RNA by Hyde, Jennifer L., Gardner, Christina L., Kimura, Taishi, White, James P., Liu, Gai, Trobaugh, Derek W., Huang, Cheng, Tonelli, Marco, Paessler, Slobodan, Takeda, Kiyoshi, Klimstra, William B., Amarasinghe, Gaya K., Diamond, Michael S.

“…Although interferon (IFN) signaling induces genes that limit viral infection, many pathogenic viruses overcome this host response. As an example, 2′-O…”
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Rapid purification of RNA secondary structures by Gelhaus, Stacy L., LaCourse, William R., Hagan, Nathan A., Amarasinghe, Gaya K., Fabris, Daniele

“…A new method for rapid purification and structural analysis of oligoribonucleotides of 19 and 20 nt is applied to RNA hairpins SL3 and SL2, which are stable…”
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Evasion of interferon responses by Ebola and Marburg viruses by Basler, Christopher F, Amarasinghe, Gaya K

“…The filoviruses, Ebola virus (EBOV) and Marburg virus (MARV), cause frequently lethal viral hemorrhagic fever. These infections induce potent cytokine…”
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Filoviral immune evasion mechanisms by Ramanan, Parameshwaran, Shabman, Reed S, Brown, Craig S, Amarasinghe, Gaya K, Basler, Christopher F, Leung, Daisy W

“…The Filoviridae family of viruses, which includes the genera Ebolavirus (EBOV) and Marburgvirus (MARV), causes severe and often times lethal hemorrhagic fever…”
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Structural and energetic mechanisms of cooperative autoinhibition and activation of vav1 by Tomchick, D. R., Yu, B., Martins, I. R. S., Li, P., Amarasinghe, G. K., Umetani, J., Fernandez-Zapico, M. E., Billadeau, D. D., Machius, M., Rosen, M. K.

“…Abstract only…”
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Acidic Region Tyrosines Provide Access Points for Allosteric Activation of the Autoinhibited Vav1 Dbl Homology Domain by Amarasinghe, Gaya K, Rosen, Michael K

“…Autoinhibited proteins serve key roles in many signal transduction pathways, and therefore proper regulation of these proteins is critical for normal cellular…”
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NMR Structure of Stem-loop SL2 of the HIV-1 [PSgr] RNA Packaging Signal Reveals a Novel A-U-A Base-triple Platform by Amarasinghe, G K, De Guzman, RN, Turner, R B, Summers, M F

“…The genome of the human immunodeficiency virus type-1 (HIV-1) contains a stretch of similar to 120 nucleotides known as the [PSgr]-site that is essential for…”
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NMR Structure of the HIV-1 Nucleocapsid Protein Bound to Stem-Loop SL2 of the [PSgr]-RNA Packaging Signal. Implications for Genome Recognition by Amarasinghe, G K, De Guzman, RN, Turner, R B, Chancellor, K, Wu, Z R, Summers, M F

“…The RNA genome of the human immunodeficiency virus type-1 (HIV-1) contains a similar to 120 nucleotide [PSgr]-packaging signal that is recognized by the…”
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